The Role of Non-Coding RNAs in Gene Regulation and Cellular Signaling Pathways DOI Creative Commons
Kiran Kumari

International Journal of Innovations in Science Engineering and Management., Год журнала: 2025, Номер unknown, С. 174 - 180

Опубликована: Фев. 22, 2025

Evidence has been mounting over the last decade demonstrating crucial functions of ncRNAs, including miRNAs and long non-coding RNAs (lncRNAs), in cellular signalling networks gene regulation. These ncRNAs are highly expressed play a role regulating processes metastasis endothelial cell invasiveness. They facilitate crosstalk between interconnected signaling pathways, PTEN/PI3K/AKT/mTOR, by acting as linking molecules within signal circuits. In addition to expression conventional apical measures, studying provides better understanding both beneficial detrimental reactions external exposures. Additionally, miRNAs—which may be found extracellular intracellular environments, such biofluids—have become potential early precise molecular indicators tissue conditions. This review highlights regulatory their involvement homeostasis, biomarkers, shedding light on significance regulation, toxicological studies, precision medicine.

Язык: Английский

The Role of Non-Coding RNAs in Gene Regulation and Cellular Signaling Pathways DOI Creative Commons
Kiran Kumari

International Journal of Innovations in Science Engineering and Management., Год журнала: 2025, Номер unknown, С. 174 - 180

Опубликована: Фев. 22, 2025

Evidence has been mounting over the last decade demonstrating crucial functions of ncRNAs, including miRNAs and long non-coding RNAs (lncRNAs), in cellular signalling networks gene regulation. These ncRNAs are highly expressed play a role regulating processes metastasis endothelial cell invasiveness. They facilitate crosstalk between interconnected signaling pathways, PTEN/PI3K/AKT/mTOR, by acting as linking molecules within signal circuits. In addition to expression conventional apical measures, studying provides better understanding both beneficial detrimental reactions external exposures. Additionally, miRNAs—which may be found extracellular intracellular environments, such biofluids—have become potential early precise molecular indicators tissue conditions. This review highlights regulatory their involvement homeostasis, biomarkers, shedding light on significance regulation, toxicological studies, precision medicine.

Язык: Английский

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