Zebrafish as a Model Organism for Congenital Hydrocephalus: Characteristics and Insights DOI
Kaiyue Wang, Zhi Tang,

Yijian Yang

и другие.

Zebrafish, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 7, 2024

Hydrocephalus is a cerebrospinal fluid-related disease that usually manifests as abnormal dilation of the ventricles, with triad clinical findings including walking difficulty, reduced attention span, and urinary frequency or incontinence. The onset congenital hydrocephalus closely related to mutations in genes regulate brain development. Currently, our understanding mechanisms remains limited, prognosis existing treatments unsatisfactory. Additionally, there are no suitable dedicated model organisms for hydrocephalus. Therefore, it significant determine mechanism develop special animal models Recently, zebrafish have emerged popular organism many fields, developmental biology, genetics, toxicology. Its genome shares high similarity humans, has fast low-cost reproduction. These advantages make studying pathogenesis therapeutic approaches various diseases, specifically diseases. This study explored possibility using review describes characteristics discusses specific models. limitations research highlighted, insights further development provided.

Язык: Английский

Developing zebrafish models of Notch-related CNS pathologies DOI
Natalia Erofeeva,

David S. Galstyan,

Longen Yang

и другие.

Neuroscience & Biobehavioral Reviews, Год журнала: 2025, Номер unknown, С. 106059 - 106059

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

Ginkgo Biloba as a niche theme cognitive enhancer agent, 1420 dokumen of Scopus database. A bibliometric study from 1988 to 2024 DOI Creative Commons
ARMAN YURISALDI SALEH,

Dwi Arwandi Yogi Saputra,

Riezky Valentina

и другие.

F1000Research, Год журнала: 2025, Номер 14, С. 275 - 275

Опубликована: Март 7, 2025

1) Introduction Cognitive enhancers, also known as nootropics, aim to improve cognitive functions, such memory and attention. Despite their potential benefits, the challenges include scientific validation, ethical considerations, regulatory hurdles. This bibliometric study analyzes literature from Scopus identify key trends, influential authors, research gaps, providing guidance for future research. 2) Methods employs a review methodology gather data database on Neuroaid, analyzing it using Biblioshiny VOSviewer software. The focus was Ginkgo Biloba niche-theme enhancer agent based data, both quantitative qualitative analyses. 3) Results discussion biloba, 'maidenhair tree’ order Ginkgoales, appeared 290 million years ago. Chinese Japanese culture has been cultivated thousands of years. tree is valued its resilience therapeutic properties, often used in traditional medicine respiratory blood circulation issues. 4) Conclusions enhancers aims provide comprehensive systematic existing literature, highlighting gaps. findings this will contribute better understanding current state inform conducted December 2024.

Язык: Английский

Процитировано

0

Zebrafish as a Model Organism for Congenital Hydrocephalus: Characteristics and Insights DOI
Kaiyue Wang, Zhi Tang,

Yijian Yang

и другие.

Zebrafish, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 7, 2024

Hydrocephalus is a cerebrospinal fluid-related disease that usually manifests as abnormal dilation of the ventricles, with triad clinical findings including walking difficulty, reduced attention span, and urinary frequency or incontinence. The onset congenital hydrocephalus closely related to mutations in genes regulate brain development. Currently, our understanding mechanisms remains limited, prognosis existing treatments unsatisfactory. Additionally, there are no suitable dedicated model organisms for hydrocephalus. Therefore, it significant determine mechanism develop special animal models Recently, zebrafish have emerged popular organism many fields, developmental biology, genetics, toxicology. Its genome shares high similarity humans, has fast low-cost reproduction. These advantages make studying pathogenesis therapeutic approaches various diseases, specifically diseases. This study explored possibility using review describes characteristics discusses specific models. limitations research highlighted, insights further development provided.

Язык: Английский

Процитировано

2