Bioactive Three-Dimensional Chitosan-Based Scaffolds Modified with Poly(dopamine)/CBD@Pt/Au/PVP Nanoparticles as Potential NGCs Applicable in Nervous Tissue Regeneration—Preparation and Characterization DOI Creative Commons
Aleksandra Sierakowska-Byczek, Adam Gałuszka,

Łukasz Janus

и другие.

Molecules, Год журнала: 2024, Номер 29(22), С. 5376 - 5376

Опубликована: Ноя. 14, 2024

Tissue engineering of nervous tissue is a promising direction in the treatment neurological diseases such as spinal cord injuries or neuropathies. Thanks to technological progress and scientific achievements; use cells; artificial scaffolds; growth factors are becoming increasingly common. Despite challenges complex structure this tissue, regenerative medicine appears future approach improve quality life patients with injuries. Until now; most functional biomaterials used for purpose were based on decellularized extra cellular matrix (ECM) nanofibrous materials, whereas current clinically verified ones cases do not exhibit bioactivity possibility external stimulation. The aim research was develop new type bioactive, chitosan-based 3D materials applicable nerve guide conduits (NGCs) modified poly(dopamine), Au/Pt coated PVP nanoparticles, cannabidiol. NGCs prepared under microwave-assisted conditions their chemical studied using FT-IR method. Next, study will discuss novel morphology swelling abilities well susceptibility biodegradation presence collagenase lysozyme. Finally, potential field has been via cytotoxicity 1321N1 human astrocytoma cell line, which confirmed biocompatibility direct contact studies.

Язык: Английский

Sinoatrial node rod cells transplantation into the injured spinal cord as a novel therapeutic approach to improve proper information transmission DOI
Mohammad Saleh Ranaiy,

Dina Rajabi Zadeh,

Mozhgan Abasi

и другие.

Medical Hypotheses, Год журнала: 2025, Номер unknown, С. 111608 - 111608

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Bioactive Three-Dimensional Chitosan-Based Scaffolds Modified with Poly(dopamine)/CBD@Pt/Au/PVP Nanoparticles as Potential NGCs Applicable in Nervous Tissue Regeneration—Preparation and Characterization DOI Creative Commons
Aleksandra Sierakowska-Byczek, Adam Gałuszka,

Łukasz Janus

и другие.

Molecules, Год журнала: 2024, Номер 29(22), С. 5376 - 5376

Опубликована: Ноя. 14, 2024

Tissue engineering of nervous tissue is a promising direction in the treatment neurological diseases such as spinal cord injuries or neuropathies. Thanks to technological progress and scientific achievements; use cells; artificial scaffolds; growth factors are becoming increasingly common. Despite challenges complex structure this tissue, regenerative medicine appears future approach improve quality life patients with injuries. Until now; most functional biomaterials used for purpose were based on decellularized extra cellular matrix (ECM) nanofibrous materials, whereas current clinically verified ones cases do not exhibit bioactivity possibility external stimulation. The aim research was develop new type bioactive, chitosan-based 3D materials applicable nerve guide conduits (NGCs) modified poly(dopamine), Au/Pt coated PVP nanoparticles, cannabidiol. NGCs prepared under microwave-assisted conditions their chemical studied using FT-IR method. Next, study will discuss novel morphology swelling abilities well susceptibility biodegradation presence collagenase lysozyme. Finally, potential field has been via cytotoxicity 1321N1 human astrocytoma cell line, which confirmed biocompatibility direct contact studies.

Язык: Английский

Процитировано

1