
Annals of Human Biology, Год журнала: 2024, Номер 51(1)
Опубликована: Ноя. 7, 2024
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder with no fully curative treatment.
Язык: Английский
Annals of Human Biology, Год журнала: 2024, Номер 51(1)
Опубликована: Ноя. 7, 2024
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder with no fully curative treatment.
Язык: Английский
Magnetic Resonance in Medical Sciences, Год журнала: 2024, Номер 23(3), С. 367 - 376
Опубликована: Янв. 1, 2024
The most commonly used neuroimaging biomarkers of brain structure, particularly in neurodegenerative diseases, have traditionally been summary measurements from ROIs derived structural MRI, such as volume and thickness. Advances MR acquisition techniques, including high-field imaging, emergence learning-based methods opened up opportunities to interrogate structure finer detail, allowing investigators move beyond macrostructural measurements. On the one hand, superior signal contrast has potential make appearance-based metrics that directly analyze intensity patterns, texture analysis radiomics features, more reliable. Quantitative at high-field, can also provide a richer set measures with greater interpretability. other use neural networks-based techniques exploit subtle patterns images now be mined advanced imaging. Finally, there are for integration multimodal data different spatial scales is enabled by developments many above techniques-for example, combining digital histopathology high-resolution ex-vivo in-vivo MRI. Some these approaches early stages development present their own challenges. Nonetheless, they hold promise drive next generation validation biomarker studies. This article will survey recent this area, particular focus on Alzheimer's disease related disorders. However, discussion equally relevant imaging neurological disorders, even organ systems interest. It not meant an exhaustive review available literature, but rather presented trends through collection representative studies eye towards what future may hold.
Язык: Английский
Процитировано
5Computer Methods and Programs in Biomedicine, Год журнала: 2025, Номер unknown, С. 108739 - 108739
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0Computer Methods and Programs in Biomedicine, Год журнала: 2025, Номер unknown, С. 108771 - 108771
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0Brain Informatics, Год журнала: 2024, Номер 11(1)
Опубликована: Дек. 1, 2024
Язык: Английский
Процитировано
1Annals of Human Biology, Год журнала: 2024, Номер 51(1)
Опубликована: Ноя. 7, 2024
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder with no fully curative treatment.
Язык: Английский
Процитировано
0