An update of the impact of pesticide exposure on memory and learning DOI Creative Commons
Karol Ferreira Honatel, Bruno Dutra Arbo, Mirna Bainy Leal

и другие.

Deleted Journal, Год журнала: 2024, Номер 1(1)

Опубликована: Ноя. 11, 2024

The dependence on the use of pesticides in agribusiness leads to an increase human exposure these chemical compounds through occupational activity, contamination environment, food and water. nervous system is target most insecticidal when are poorly selective, they can harm non-target species, including humans. This work aimed investigate effects pesticide memory learning. Articles published PubMed database between 2015 2024 were reviewed. One hundred sixty-one articles included this review, which one thirty two preclinical studies twenty-nine studies. Among studies, organophosphates, pyrethroids, neonicotinoids, carbamates, addition herbicides, fungicides mixed exposures was associated with learning deficits animals such as bees, mosquitoes, fishes, mice, rats, bats. Olfactory, associative aversive learning, well capacity affected by pesticides. Most evaluated environmental organophosphate pesticides, pyrethroids carbamates outcomes interest. Living close application areas having parents working agriculture worse scores childhood adolescence. Prenatal insecticides has already been poorer attention skills attention-deficit/hyperactivity disorder (ADHD) symptoms, intellectual disability, autism spectrum disorder, motor delays, problems. In adults, during activity also performance. evidence found review suggests that different mechanisms action able cause some cognitive impairment. Developmental exposure, chronic contribute performance, especially memory.

Язык: Английский

Atrazine toxicity and its adverse effects on different systems of the human body DOI
Srijit Das, Srinivasa Rao Sirasanagandla

Elsevier eBooks, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Atrazine exposure induces abnormal swimming behavior of tadpoles under light and/or dark stimuli: A comprehensive multi-omics insights from eyes and brain DOI
Jiawei Yin,

Minyi Huang,

Zijie Zeng

и другие.

Aquatic Toxicology, Год журнала: 2025, Номер unknown, С. 107396 - 107396

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0
Hypoactivity and neurochemical alterations in the basal ganglia of female Sprague-Dawley rats after repeated exposure to atrazine DOI Creative Commons

Triana Acevedo-Huergo,

Jonathan Sánchez-Yépez,

María Soledad Mendoza-Trejo

и другие.

Frontiers in Toxicology, Год журнала: 2024, Номер 6

Опубликована: Авг. 5, 2024

The herbicide atrazine (ATR) has been one of the most widely used herbicides worldwide. However, due to its indiscriminate use, it considered an environmental contaminant. Several studies have classified ATR as endocrine disruptor, and found neurotoxic effects on behavior, along with alterations in dopaminergic, GABAergic, glutamatergic systems basal ganglia male rodents. These findings suggest that these neurotransmitter are targets this herbicide. there no evaluating neurotoxicity female Our study aimed assess repeated IP injections 100 mg ATR/kg or a vehicle every other day for 2 weeks (six injections) locomotor activity, content monoamines, GABA, glutamate, glutamine striatum, nucleus accumbens, ventral midbrain, prefrontal cortex, tyrosine hydroxylase (TH) protein levels striatum accumbens rats. Repeated immediately decreased all activity parameters evaluated, such hypoactivity persisted at least 48 h after last administration. administration increased dopamine DOPAC serotonin 5-HIAA midbrain. In contrast, TH were similar between groups. Meanwhile, glutamine, glutamate remained unaltered brain regions evaluated. observed behavioral could be associated monoamine changes presented by data reveal midbrain susceptible exposure

Язык: Английский

Процитировано

0
An update of the impact of pesticide exposure on memory and learning DOI Creative Commons
Karol Ferreira Honatel, Bruno Dutra Arbo, Mirna Bainy Leal

и другие.

Deleted Journal, Год журнала: 2024, Номер 1(1)

Опубликована: Ноя. 11, 2024

The dependence on the use of pesticides in agribusiness leads to an increase human exposure these chemical compounds through occupational activity, contamination environment, food and water. nervous system is target most insecticidal when are poorly selective, they can harm non-target species, including humans. This work aimed investigate effects pesticide memory learning. Articles published PubMed database between 2015 2024 were reviewed. One hundred sixty-one articles included this review, which one thirty two preclinical studies twenty-nine studies. Among studies, organophosphates, pyrethroids, neonicotinoids, carbamates, addition herbicides, fungicides mixed exposures was associated with learning deficits animals such as bees, mosquitoes, fishes, mice, rats, bats. Olfactory, associative aversive learning, well capacity affected by pesticides. Most evaluated environmental organophosphate pesticides, pyrethroids carbamates outcomes interest. Living close application areas having parents working agriculture worse scores childhood adolescence. Prenatal insecticides has already been poorer attention skills attention-deficit/hyperactivity disorder (ADHD) symptoms, intellectual disability, autism spectrum disorder, motor delays, problems. In adults, during activity also performance. evidence found review suggests that different mechanisms action able cause some cognitive impairment. Developmental exposure, chronic contribute performance, especially memory.

Язык: Английский

Процитировано

0