The Journal of Machine Learning for Biomedical Imaging,
Год журнала:
2023,
Номер
2(MLCN 2022), С. 338 - 360
Опубликована: Авг. 29, 2023
Intracranial
hemorrhage
(ICH)
is
a
life-threatening
medical
emergency
that
requires
timely
and
accurate
diagnosis
for
effective
treatment
improved
patient
survival
rates.
While
deep
learning
techniques
have
emerged
as
the
leading
approach
image
analysis
processing,
most
commonly
employed
supervised
often
large,
high-quality
annotated
datasets
can
be
costly
to
obtain,
particularly
pixel/voxel-wise
segmentation.
To
address
this
challenge
facilitate
ICH
decisions,
we
introduce
novel
weakly
method
segmentation,
utilizing
Swin
transformer
trained
on
an
classification
task
with
categorical
labels.
Our
leverages
hierarchical
combination
of
head-wise
gradient-infused
self-attention
maps
generate
Additionally,
conducted
exploratory
study
different
strategies
showed
binary
has
more
positive
impact
compared
full
subtyping.
With
mean
Dice
score
0.44,
our
technique
achieved
similar
segmentation
performance
popular
U-Net
Swin-UNETR
models
supervision
outperformed
using
GradCAM,
demonstrating
excellent
potential
proposed
framework
in
challenging
tasks.
code
available
at
<a
href='https://github.com/HealthX-Lab/HGI-SAM'>https://github.com/HealthX-Lab/HGI-SAM</a>
Journal of NeuroInterventional Surgery,
Год журнала:
2022,
Номер
15(3), С. 262 - 271
Опубликована: Ноя. 14, 2022
Background
Subarachnoid
hemorrhage
from
cerebral
aneurysm
rupture
is
a
major
cause
of
morbidity
and
mortality.
Early
identification,
aided
by
automated
systems,
may
improve
patient
outcomes.
Therefore,
systematic
review
meta-analysis
the
diagnostic
accuracy
artificial
intelligence
(AI)
algorithms
in
detecting
aneurysms
using
CT,
MRI
or
DSA
was
performed.
Methods
MEDLINE,
Embase,
Cochrane
Library
Web
Science
were
searched
until
August
2021.
Eligibility
criteria
included
studies
fully
to
detect
MRI,
CT
DSA.
Following
Preferred
Reporting
Items
for
Systematic
Reviews
Meta-Analysis:
Diagnostic
Test
Accuracy
(PRISMA-DTA),
articles
assessed
Quality
Assessment
Studies
2
(QUADAS-2).
Meta-analysis
bivariate
random-effect
model
determine
pooled
sensitivity,
specificity,
area
under
receiver
operator
characteristic
curve
(ROC-AUC).
PROSPERO:
CRD42021278454.
Results
43
included,
41/43
(95%)
retrospective.
34/43
(79%)
used
AI
as
standalone
tool,
while
9/43
(21%)
assisting
reader.
23/43
(53%)
deep
learning.
Most
had
high
bias
risk
applicability
concerns,
limiting
conclusions.
Six
gave
(pooled)
91.2%
(95%
CI
82.2%
95.8%)
sensitivity;
16.5%
9.4%
27.1%)
false-positive
rate
(1-specificity);
0.936
ROC-AUC.
Five
reader-assistive
90.3%
88.0%
–
92.2%)
7.9%
3.5%
16.8%)
rate;
0.910
Conclusion
has
potential
support
clinicians
aneurysms.
Interpretation
limited
due
poor
generalizability.
Multicenter,
prospective
are
required
assess
clinical
practice.
Neuroinformatics,
Год журнала:
2022,
Номер
21(1), С. 21 - 34
Опубликована: Авг. 18, 2022
Abstract
Brain
aneurysm
detection
in
Time-Of-Flight
Magnetic
Resonance
Angiography
(TOF-MRA)
has
undergone
drastic
improvements
with
the
advent
of
Deep
Learning
(DL).
However,
performances
supervised
DL
models
heavily
rely
on
quantity
labeled
samples,
which
are
extremely
costly
to
obtain.
Here,
we
present
a
model
for
that
overcomes
issue
“weak”
labels:
oversized
annotations
considerably
faster
create.
Our
weak
labels
resulted
be
four
times
generate
than
their
voxel-wise
counterparts.
In
addition,
our
leverages
prior
anatomical
knowledge
by
focusing
only
plausible
locations
occurrence.
We
first
train
and
evaluate
through
cross-validation
an
in-house
TOF-MRA
dataset
comprising
284
subjects
(170
females
/
127
healthy
controls
157
patients
198
aneurysms).
On
this
dataset,
best
achieved
sensitivity
83%,
False
Positive
(FP)
rate
0.8
per
patient.
To
assess
generalizability,
then
participated
challenge
data
(93
patients,
20
controls,
125
public
challenge,
was
68%
(FP
=
2.5),
ranking
4th/18
open
leaderboard.
found
no
significant
difference
between
risk-of-rupture
groups
(
p
0.75),
0.72),
or
sizes
0.15).
Data,
code
weights
released
under
permissive
licenses.
demonstrate
can
alleviate
necessity
prohibitively
expensive
annotations.
IEEE Transactions on Medical Imaging,
Год журнала:
2023,
Номер
42(11), С. 3451 - 3460
Опубликована: Июнь 23, 2023
Early
detection
of
unruptured
intracranial
aneurysms
(UIAs)
enables
better
rupture
risk
and
preventative
treatment
assessment.
UIAs
are
usually
diagnosed
on
Time-of-Flight
Magnetic
Resonance
Angiographs
(TOF-MRA)
or
contrast-enhanced
Computed
Tomography
(CTA).
Various
automatic
voxel-based
deep
learning
UIA
methods
have
been
developed,
but
these
limited
to
a
single
modality.
We
propose
modality-independent
method
using
geometric
model
with
high
resolution
surface
meshes
brain
vessels.
A
mesh
convolutional
neural
network
ResU-Net
style
architecture
was
used.
performance
investigated
different
input
pooling
resolutions,
including
additional
edge
features
(shape
index
curvedness).
Both
higher
(15,000
edges)
curvature
improved
(average
sensitivity:
65.6%,
false
positive
count/image
(FPC/image):
1.61).
were
detected
in
an
independent
TOF-MRA
test
set
CTA
average
sensitivity
52.0%
48.3%
FPC/image
1.04
1.05
respectively.
provide
deep-learning
vascular
comparable
state-of-the-art
methods.
Medical Image Analysis,
Год журнала:
2023,
Номер
91, С. 103029 - 103029
Опубликована: Ноя. 19, 2023
Imaging
markers
of
cerebral
small
vessel
disease
provide
valuable
information
on
brain
health,
but
their
manual
assessment
is
time-consuming
and
hampered
by
substantial
intra-
interrater
variability.
Automated
rating
may
benefit
biomedical
research,
as
well
clinical
assessment,
diagnostic
reliability
existing
algorithms
unknown.
Here,
we
present
the
results
VAscular
Lesions
DetectiOn
Segmentation
(Where
VALDO?)
challenge
that
was
run
a
satellite
event
at
international
conference
Medical
Image
Computing
Computer
Aided
Intervention
(MICCAI)
2021.
This
aimed
to
promote
development
methods
for
automated
detection
segmentation
sparse
imaging
disease,
namely
enlarged
perivascular
spaces
(EPVS)
(Task
1),
microbleeds
2)
lacunes
presumed
vascular
origin
3)
while
leveraging
weak
noisy
labels.
Overall,
12
teams
participated
in
proposing
solutions
one
or
more
tasks
(4
Task
1
-
EPVS,
9
2
Microbleeds
6
3
Lacunes).
Multi-cohort
data
used
both
training
evaluation.
Results
showed
large
variability
performance
across
tasks,
with
promising
notably
EPVS
not
practically
useful
yet
Lacunes.
It
also
highlighted
inconsistency
cases
deter
use
an
individual
level,
still
proving
population
level.
Journal of The Royal Society Interface,
Год журнала:
2024,
Номер
21(211)
Опубликована: Фев. 1, 2024
Vascular
flow
modelling
can
improve
our
understanding
of
vascular
pathologies
and
aid
in
developing
safe
effective
medical
devices.
models
typically
involve
solving
the
nonlinear
Navier-Stokes
equations
complex
anatomies
using
physiological
boundary
conditions,
often
presenting
a
multi-physics
multi-scale
computational
problem
to
be
solved.
This
leads
highly
expensive
that
require
excessive
time.
review
explores
accelerated
simulation
methodologies,
specifically
focusing
on
modelling.
We
reduced
order
(ROM)
techniques
like
zero-/one-dimensional
modal
decomposition-based
ROMs
machine
learning
(ML)
methods
including
ML-augmented
ROMs,
ML-based
physics-informed
ML
models.
discuss
applicability
each
method
acceleration
effectiveness
addressing
domain-specific
challenges.
When
available,
we
provide
statistics
accuracy
speed-up
factors
for
various
applications
related
acceleration.
Our
findings
indicate
type
model
has
strengths
limitations
depending
context.
To
accelerate
real-world
problems,
propose
future
research
capable
handling
significant
geometric
variability
inherent
such
problems.
BMC Medical Imaging,
Год журнала:
2024,
Номер
24(1)
Опубликована: Июль 2, 2024
Abstract
Background
The
detection
and
management
of
intracranial
aneurysms
(IAs)
are
vital
to
prevent
life-threatening
complications
like
subarachnoid
hemorrhage
(SAH).
Artificial
Intelligence
(AI)
can
analyze
medical
images,
CTA
or
MRA,
spotting
nuances
possibly
overlooked
by
humans.
Early
facilitates
timely
interventions
improved
outcomes.
Moreover,
AI
algorithms
offer
quantitative
data
on
aneurysm
attributes,
aiding
in
long-term
monitoring
assessing
rupture
risks.
Methods
We
screened
four
databases
(PubMed,
Web
Science,
IEEE
Scopus)
for
studies
using
artificial
intelligence
identify
IA.
Based
algorithmic
methodologies,
we
categorized
them
into
classification,
segmentation,
combined,
then
their
merits
shortcomings
compared.
Subsequently,
elucidate
potential
challenges
that
contemporary
might
encounter
within
real-world
clinical
diagnostic
contexts.
Then
outline
prospective
research
trajectories
underscore
key
concerns
this
evolving
field.
Results
Forty-seven
IA
recognition
based
were
included
search
screening
criteria.
retrospective
results
represent
current
different
modal
images
predict
risk
blockage.
In
diagnosis,
effectively
improve
the
accuracy
reduce
missed
false
positives.
Conclusions
algorithm
detect
unobtrusive
more
accurately
communicating
arteries
cavernous
sinus
avoid
further
expansion.
addition,
analyzing
blockage
before
after
surgery
help
doctors
plan
treatment
uncertainties
process.