Advanced Functional Materials,
Год журнала:
2021,
Номер
31(34)
Опубликована: Май 30, 2021
Abstract
Being
capable
of
dealing
with
both
electrical
signals
and
light,
artificial
optoelectronic
synapses
are
great
importance
for
neuromorphic
computing
receiving
a
burgeoning
amount
interest
in
visual
information
processing.
In
this
work,
an
synapse
composed
Al/TiN
x
O
2–
/MoS
2
/ITO
(H‐OSD)
is
proposed
experimentally
realized.
The
H‐OSD
can
enable
basic
voltage‐induced
synaptic
functions
such
as
the
long/short‐term
plasticity
moreover
be
electrically
adjusted.
response
to
light
stimuli,
versatile
advanced
including
memory,
learning‐forgetting‐relearning
successfully
demonstrated,
which
could
enhance
processing
capability
computing.
Most
importantly,
based
on
these
light‐induced
salient
features,
4
×
array
developed
show
potential
application
constructing
system.
It
shown
that
perceiving
memorizing
respectively
relevant
perception
memory
functions,
readily
attained
through
tuning
intensity
number
illuminations.
As
such,
shows
potentials
will
facilitate
applications
electronic
eyes
light‐driven
neurorobotics.
Cold Spring Harbor Perspectives in Biology,
Год журнала:
2011,
Номер
4(1), С. a005736 - a005736
Опубликована: Ноя. 15, 2011
Gina
Turrigiano
Department
of
Biology
and
Center
for
Behavioral
Genomics,
Brandeis
University,
Waltham,
Massachusetts
02493
Correspondence:
turrigiano{at}brandeis.edu
Journal of Neuroscience,
Год журнала:
2010,
Номер
30(45), С. 14964 - 14971
Опубликована: Ноя. 10, 2010
Adult
brain
plasticity,
although
possible,
remains
more
restricted
in
scope
than
during
development.
Here,
we
address
conditions
under
which
circuit
rewiring
may
be
facilitated
the
mature
brain.
At
a
cellular
and
molecular
level,
adult
plasticity
is
actively
limited.
Some
of
these
"brakes"
are
structural,
such
as
perineuronal
nets
or
myelin,
inhibit
neurite
outgrowth.
Others
functional,
acting
directly
upon
excitatory-inhibitory
balance
within
local
circuits.
Plasticity
adulthood
can
induced
either
by
lifting
brakes
through
invasive
interventions
exploiting
endogenous
permissive
factors,
neuromodulators.
Using
amblyopic
visual
system
model,
discuss
genetic,
pharmacological,
environmental
removal
to
enable
recovery
vision
rodents.
Although
mechanisms
remain
largely
uncharted
human,
consider
how
they
provide
biological
foundation
for
remarkable
increase
after
action
video
game
play
subjects.
Physiological Reviews,
Год журнала:
2011,
Номер
91(2), С. 555 - 602
Опубликована: Апрель 1, 2011
Axons
are
generally
considered
as
reliable
transmission
cables
in
which
stable
propagation
occurs
once
an
action
potential
is
generated.
Axon
dysfunction
occupies
a
central
position
many
inherited
and
acquired
neurological
disorders
that
affect
both
peripheral
neurons.
Recent
findings
suggest
the
functional
computational
repertoire
of
axon
much
richer
than
traditionally
thought.
Beyond
classical
axonal
propagation,
intrinsic
voltage-gated
ionic
currents
together
with
geometrical
properties
determine
several
complex
operations
not
only
control
signal
processing
brain
circuits
but
also
neuronal
timing
synaptic
efficacy.
evidence
for
implication
these
forms
computation
short-term
dynamics
communication
discussed.
Finally,
we
review
how
activity
regulates
morphology
function
on
long-term
time
scale
during
development
adulthood.
Neuron,
Год журнала:
2013,
Номер
80(2), С. 335 - 342
Опубликована: Окт. 1, 2013
Highlights•Cortical
neurons
in
vivo
return
to
a
homeostatic
firing
rate
set
point
when
perturbed•Firing
homeostasis
is
expressed
cell-type-specific
manner•Homeostatic
points
are
across
sleep
and
wake
states•Firing
correlated
with
the
induction
of
synaptic
scalingSummaryIt
has
been
postulated
that
mechanisms
maintain
stable
circuit
function
by
keeping
neuronal
within
range,
but
such
never
demonstrated
vivo.
Here
we
use
chronic
multielectrode
recordings
monitor
rates
visual
cortex
freely
behaving
rats
during
monocular
deprivation
(MD).
Firing
V1
were
suppressed
over
first
2
day
MD
then
rebounded
baseline
next
2–3
days
despite
continued
MD.
This
drop
rebound
was
accompanied
bidirectional
changes
mEPSC
amplitude
measured
ex
The
independent
sleep-wake
state
cell
type
specific,
as
putative
FS
regular
spiking
responded
different
time
courses.
These
data
establish
intact
CNS
act
stabilize
face
sustained
sensory
perturbations.
The Journal of Physiology,
Год журнала:
2016,
Номер
595(4), С. 1273 - 1288
Опубликована: Окт. 13, 2016
Applications
of
transcranial
direct
current
stimulation
to
modulate
human
neuroplasticity
have
increased
in
research
and
clinical
settings.
However,
the
need
for
longer-lasting
effects,
combined
with
marked
inter-individual
variability,
necessitates
a
deeper
understanding
relationship
between
parameters
physiological
effects.
We
systematically
investigated
full
DC
intensity
range
(0.5-2.0
mA)
both
anodal
cathodal
tDCS
sham-controlled
repeated
measures
design,
monitoring
changes
motor-cortical
excitability
via
magnetic
up
2
h
after
stimulation.
For
polarities,
after-effects
did
not
linearly
correlate
increasing
intensity;
effects
lower
intensities
(0.5,
1.0
showed
equal,
if
greater
excitability.
Further,
while
intra-individual
responses
good
reliability,
sensitivity
TMS
accounted
modest
percentage
variance
early
mA
tDCS,
which
may
be
practical
relevance
future
optimizations.
