The Encoding of Speech Sounds in the Superior Temporal Gyrus

Neuron, Год журнала: 2019, Номер 102(6), С. 1096 - 1110

Опубликована: Июнь 1, 2019

Язык: Английский

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Proactive Sensing of Periodic and Aperiodic Auditory Patterns

Trends in Cognitive Sciences, Год журнала: 2018, Номер 22(10), С. 870 - 882

Опубликована: Сен. 25, 2018

Язык: Английский

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Plasticity of intrinsic neuronal excitability

Current Opinion in Neurobiology, Год журнала: 2018, Номер 54, С. 73 - 82

Опубликована: Сен. 19, 2018

Язык: Английский

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Parametric control of flexible timing through low-dimensional neural manifolds

Neuron, Год журнала: 2023, Номер 111(5), С. 739 - 753.e8

Опубликована: Янв. 13, 2023

Язык: Английский

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Neural Sequences as an Optimal Dynamical Regime for the Readout of Time

Neuron, Год журнала: 2020, Номер 108(4), С. 651 - 658.e5

Опубликована: Сен. 17, 2020

Язык: Английский

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All in Good Time: Long-Lasting Postdictive Effects Reveal Discrete Perception

Trends in Cognitive Sciences, Год журнала: 2020, Номер 24(10), С. 826 - 837

Опубликована: Сен. 3, 2020

Conscious perception seems to be a continuous stream of percepts. Is this true? Recent research sheds new light on age-old debate.In long-lasting postdictive effects, later events can determine the that occurred several hundreds milliseconds earlier.Long-lasting postdiction requires high capacity buffers, which store information unconsciously for substantial periods time. This favors two-stage model, in unconscious processing precedes discrete conscious percepts.Such model solves problems both traditional and models. consciousness percepts or is it discrete, occurring only at certain moments time? question has puzzled philosophers, psychologists, neuroscientists centuries. Both hypotheses have fallen repeatedly out favor. Here, we review recent studies exploring effects show results favor precede We propose such marries advantages models resolves centuries old debates about consciousness. Intuitively, Imagine diver jumping from cliff down into ocean. feel see their motion trajectory each moment For reason, most philosophical [1.Dainton B. Temporal consciousness.in: Zalta E.N. The Stanford Encyclopedia Philosophy Winter 2018. Metaphysics Research Lab, University, 2018Google Scholar] (Box 1). However, despite intuitive appeal, theories face number [2.Doerig A. et al.Building block by block: response Fekete al..Neurosci. Conscious. 2019; (Published online January 28, 2019. https://doi.org/10.1093/nc/niy012)Crossref PubMed Scopus (10) Google Scholar, 3.Herzog M.H. al.Time slices: what duration percept?.PLoS Biol. 2016; 14e1002433Crossref (90) 4.VanRullen R. Koch C. continuous?.Trends Cogn. Sci. 2003; 7: 207-213Abstract Full Text PDF (421) Scholar]. In particular, sensory must integrated over time before motion, melodies, etc. perceived. Hence, cannot happen instantly.Box 1Philosophical ModelsMore than 1500 years ago, Saint Augustine was driven despair [98.Augustine S. Les confessions de Augustin. Charpentier, Libraire-Editeur, 1841Google Since an infinitesimally short presence exists, he thought But how then perceive change, since encompass past future events? proposed aspects come memory (such are called cinematic models). humans directly, not through memory. subsequent philosophers [99.Husserl E. Phenomenology internal time-consciousness. Marinus Hijhoff, Hague1928/1964Google contain retentional Retentional code temporal nontemporal format, similar color red coded neuron. example, sliding windows, constantly combined few milliseconds, one way implement 2). More short. They rather last amounts time; is, extended extensional During these periods, directly example.In accordance with intuition, seen as classic (continuous consciousness; left column). psychology, focused less long percept lasts. Rather asked whether all times (right column) (left Many known ancient Buddhist times, Combining psychological directions, arrive six types (Figure I). Our I, middle-right panel). classification follows (see [51.Lee G. experience structure experience.Philos. Impr. 2014; 14: 1-21Google Scholar,100.Miller J. Discrete human processing: Theoretical distinctions empirical results.Acta Psychol. 1988; 67: 191-257Crossref (232) other classifications). example. consciousness, occur time, been Traditionally, determined resolution Glossary) [4.VanRullen 5.Pöppel A hierarchical perception.Trends 1997; 1: 56-61Abstract (479) 6.Pöppel Pre-semantically defined windows cognitive processing.Philos. Trans. Soc. Lond. B 2009; 364: 1887-1896Crossref (138) 7.Allport D.A. Phenomenal simultaneity perceptual hypothesis.Br. 1968; 59: 395-406Crossref (140) two lines perceived simultaneous even when presented delay 40 ms [8.Kristofferson A.B. Attention psychophysical time.Acta 1967; 27: 93-100Crossref (85) 9.Elliott M.A. al.The subthreshold synchrony simultaneity.Psychol. Res. 2007; 71: 687-693Crossref (23) 10.White P.A. series frames?.Conscious. 2018; 60: 98-126Crossref (36) longer delays nonsimultaneity detected. Thus, may seem long. depends strongly stimulus paradigm parameters, extending orders magnitude 3 (apparent motion; [11.Westheimer McKee S.P. Perception order adjacent visual stimuli.Vis. 1977; 17: 887-892Crossref (77) Scholar]) 100 (color change during [12.Holcombe A.O. Seeing slow seeing fast: limits 13: 216-221Abstract (155) Scholar,13.Moutoussis K. Zeki direct demonstration asynchrony vision.Philos. 264: 393-399Google Scholar]). there no universal percepts, challenging general [3.Herzog Scholar,10.White call problem multiple resolutions Much discussion centers shorter low level mechanisms, persistence neural latencies (<100 ms), support [6.Pöppel Scholar,14.Breitmeyer Öğmen H. Visual Masking: Time Slices Unconscious Vision. Oxford University Press, 2006Crossref (387) 15.Efron present.Ann. N. Y. Acad. 138: 713-729Crossref (108) 16.Holcombe organization perception.in: Wagemans Handbook Perceptual Organization. 2013: 820-840Google 17.Montemayor Wittmann M. varieties presence: levels integration.Timing Percept. 2: 325-338Crossref Recently, brought debate territory beyond reach provoking rethinking Scholar,3.Herzog Scholar,18.VanRullen cycles.Trends 20: 723-735Abstract (308) 19.White three-second "subjective present": critical proposal.Psychol. Bull. 2017; 143: 735Crossref (24) 20.Fekete T. al.In interest saving time: critique perception.Neurosci. April 19, https://doi.org/10.1093/nc/niy003)Crossref argue investigating parameters content but provide upper lower bounds. literature explain Finally, outline important implications neuroscience, philosophy. Investigating challenging. measure subjective stimulus. open itself As mentioned, often used percept. (i.e., occur, etc.) logically independent. if detection ms, tells us detector, operate fully unconsciously. It does themselves nor continuous. Nevertheless, show, bounds perception. late affect another earlier, differs priming, where earlier stimuli ones. mutually bring truly fusion, disk followed 40-ms green same location. single yellow [21.Efron Conservation systems.Percept. Psychophys. 1973; 518-530Crossref (60) Scholar,22.Pilz K.S. al.Long-lasting integration form, revealed masking.J. Vis. 2013; 1312–12Crossref (11) There representations disks influence form 80 ms; second appeared. empirically investigate lasts occurs. SQM [23.Otto T.U. flight path phoenix – visible trace invisible elements vision.J. 2006; 6: 1079-1086Crossref (61) Scholar,24.Otto al.Feature across space, orientation.J. Exp. Hum. Perform. 35: 1670-1686Crossref (25) 1), sequence vertical presented, eliciting diverging streams. When horizontal vernier offset, offset direction though they fact straight. Observers easily report vs right) locate specific line carries verniers present stream, offsets integrate spatiotemporally precise. within integrate; segregate different streams Most importantly, mandatory. Even observers told unable separately 1; [25.Drissi-Daoudi L. windows.Nat. Commun. 10: 1-8Crossref (19) offset; access individual offsets. mandatory mutual up 450 depending observer. If 490 apart, reported individually period occurs bound ~400 ms. Furthermore, temporally discrete. three (at 0, 330, first integrate. third independently, twice close (160 330 ms). window lasting Similar variety paradigms. rapid serial presentation (RSVP) task, 240 [26.Akyürek E.G. Wolff M.J. Extended presentation: Attentional control Lag 1 beyond.Acta 168: 50-64Crossref (16) cue 400 after faint Gabor grating consciously 2A ; [27.Sergent al.Cueing attention gone retrospectively trigger perception.Curr. 23: 150-155Abstract (92) 28.Sergent offline representations.Philos. 373: 20170349Crossref (18) 29.Thibault al.Retrospective gates stimuli.PLoS One. 11e0148504Crossref (26) 30.Xia triggering interstimulus interaction.J. 163–3Crossref (8) volition 300 [31.Sun al.Back future: volitional apparent direction.Vis. 140: 133-139Crossref (5) Long-lasting restricted vision also audition [32.McWalter McDermott J.H. Illusory sound texture reveals multi-second statistical completion auditory scene analysis.Nat. 1-18Crossref (13) modalities [33.Sergent al.Top-down modulation early cortex supports successful postcued report.J. Neurosci. 2011; 1921-1934Crossref (28) Scholar,34.Rimsky-Robert D. cues improve near-threshold targets.Sci. 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Motion awareness.Science. 2000; 287: 2036-2038Crossref (397) example masking, masks target do interfere anymore [14.Breitmeyer Still, short, later, emphasizing again instance, shown visibility masking decoded brain imaging data >250 onset, 2C; [41.Del Cul al.Brain dynamics underlying nonlinear threshold consciousness.PLoS 5e260Crossref (511) Scholar,42.King J.-R. mechanisms brief maintenance unseen information.Neuron. 92: 1122-1134Abstract (98) Similarly, RSVP tasks, images cohabit ones available elicit activity around 350 [43.Marti Dehaene selection streams.Nat. 1-13Crossref (50) Relatedly, crossmodal 120 take more 200 [44.Fiebelkorn I.C. al.Staying lines: formation visuospatial boundaries influences multisensory feature integration.Eur. 2010; 31: 1737-1743Crossref unclear electroencephalography event-related potentials (e.g., VAN P300 ms) linked [45.Koivisto Revonsuo Event-related potential correlates awareness.Neurosci. Biobehav. Rev. 34: 922-934Crossref (178) Scholar], suggest form. Percepts altered transcranial magnetic stimulation (TMS) [46.Scharnowski F. stimulation.J. 91–1Crossref (35) Two succession 30 each. fuse resulting aligned vernier, similarly fusion mentioned before. TMS modulates 370 ms: pulses, fused predominantly while dominates pulses. independent Therefore, durations, modified postdictively. shown, interact emerges. Elements segregate, suppressed, fused, potentially more. suggests windows. How complex explained? Classically, interactions between distinct discussed terms low-level processing, [47.Eriksen C.W. Collins Some characteristics pattern perception.J. 74: 476Crossref (195) latency differences [16.Holcombe typically assumed [48.Lamme V.A. Roelfsema P.R. modes offered feedforward recurrent processing.Trends 571-579Abstract (1583) 49.Foxe J.J. Simpson G.V. Flow activation V1 frontal humans.Exp. Brain 2002; 142: 139-150Crossref (523) 50.Center al.Examining role feedback TMS-induced suppression: cautionary tale.Conscious. 75: 102805Crossref (4) explained proposing mask catches because processed latency. timescale too explanations. avenues explanation: delayed models, substantially delayed, always Continuous windows: output continuously delivered [20.Fekete Scholar,51.Lee (R. Grush, unpublished). would create many (we too-many-percepts problem; Box 2; Scholar,2.Doerig SQM, large parts empty pre-SQM screen offset. p

Язык: Английский

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Scalable representation of time in the hippocampus

Science Advances, Год журнала: 2021, Номер 7(6)

Опубликована: Фев. 3, 2021

Temporal information represented in the hippocampus is scalable.

Язык: Английский

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The amplitude in periodic neural state trajectories underlies the tempo of rhythmic tapping

PLoS Biology, Год журнала: 2019, Номер 17(4), С. e3000054 - e3000054

Опубликована: Апрель 8, 2019

Our motor commands can be exquisitely timed according to the demands of environment, and ability generate rhythms different tempos is a hallmark musical cognition. Yet, neuronal underpinnings behind rhythmic tapping remain elusive. Here, we found that activity hundreds primate medial premotor cortices (MPCs; pre-supplementary area [preSMA] supplementary [SMA]) neurons show strong periodic pattern becomes evident when their responses are projected into state space using dimensionality reduction analysis. We encoded by circular trajectories travelled at constant speed but with radii, this code highly resilient number participating neurons. Crucially, changes in amplitude oscillatory dynamics signature duration encoding during timing, regardless whether it guided an external metronome or internally controlled not result repetitive commands. This dynamic signal predicted rhythmically produced intervals on trial-by-trial basis. Furthermore, increase variability neural accounted for scalar property, feature temporal processing across tasks species. Finally, interval-dependent increments radius larger engaged production longer intervals. results support notion timing behaviors radial curvature MPC population trajectories.

Язык: Английский

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How Outcome Uncertainty Mediates Attention, Learning, and Decision-Making

Trends in Neurosciences, Год журнала: 2020, Номер 43(10), С. 795 - 809

Опубликована: Июль 28, 2020

Язык: Английский

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Contribution of the Cerebellum and the Basal Ganglia to Language Production: Speech, Word Fluency, and Sentence Construction—Evidence from Pathology

The Cerebellum, Год журнала: 2020, Номер 20(2), С. 282 - 294

Опубликована: Окт. 29, 2020

Abstract Evidence reported in recent decades increasingly confirms that both the cerebellum and basal ganglia, which are primarily involved movement control, also have a significant role vast range of cognitive affective functions. from pathology indicates disorders some aspects language production follow damage or respectively i.e., speech, word fluency, sentence construction, identifiable neuropsychological profiles most manifestations can be specifically attributed to dysfunctions mechanisms supported by one other these structures. The ganglia reciprocally interconnected. Thus, it is plausible observed when involves structures could remote effects abnormal activity other. However, purely clinical-neuropsychological perspective, primary network difficult disentangle. Functional neuroimaging non-invasive brain stimulation techniques likely represent indispensable support for achieving this goal.

Язык: Английский

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