Navigating for reward

Nature reviews. Neuroscience, Год журнала: 2021, Номер 22(8), С. 472 - 487

Опубликована: Июль 6, 2021

Язык: Английский

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Assessments of dentate gyrus function: discoveries and debates

Nature reviews. Neuroscience, Год журнала: 2023, Номер 24(8), С. 502 - 517

Опубликована: Июнь 14, 2023

Язык: Английский

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Neural dynamics underlying associative learning in the dorsal and ventral hippocampus

Nature Neuroscience, Год журнала: 2023, Номер 26(5), С. 798 - 809

Опубликована: Апрель 3, 2023

Язык: Английский

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Differential Emergence and Stability of Sensory and Temporal Representations in Context-Specific Hippocampal Sequences

Neuron, Год журнала: 2020, Номер 108(5), С. 984 - 998.e9

Опубликована: Сен. 18, 2020

Язык: Английский

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Olfactory landmarks and path integration converge to form a cognitive spatial map

Neuron, Год журнала: 2021, Номер 109(24), С. 4036 - 4049.e5

Опубликована: Окт. 27, 2021

Язык: Английский

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The hearing hippocampus

Progress in Neurobiology, Год журнала: 2022, Номер 218, С. 102326 - 102326

Опубликована: Июль 20, 2022

The hippocampus has a well-established role in spatial and episodic memory but broader function been proposed including aspects of perception relational processing. Neural bases sound analysis have described the pathway to auditory cortex, wider networks supporting cognition are still being established. We review what is known about processing information, how itself shaped by sound. In examining imaging, recording, lesion studies species from rodents humans, we uncover hierarchy hippocampal responses during passive exposure, active listening, learning associations between sounds other stimuli. describe hippocampus' connectivity computational architecture allow it track manipulate information – whether form speech, music, or environmental, emotional, phantom sounds. Functional structural correlates experience also identified. extent auditory-hippocampal interactions consistent with view that makes broad contributions cognition, beyond memory. More deeply understanding these may unlock applications entraining rhythms support intervening links hearing loss dementia.

Язык: Английский

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Prefrontal feature representations drive memory recall

Nature, Год журнала: 2022, Номер 608(7921), С. 153 - 160

Опубликована: Июль 13, 2022

Язык: Английский

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Parallel processing of sensory cue and spatial information in the dentate gyrus

Cell Reports, Год журнала: 2022, Номер 38(3), С. 110257 - 110257

Опубликована: Янв. 1, 2022

During exploration, animals form an internal map of environment by combining information about landmarks and the animal's movement, a process that depends on hippocampus. The dentate gyrus (DG) is first stage hippocampal circuit where self-motion ("where") sensory cue ("what") are integrated, but it remains unknown how DG neurons encode this during cognitive formation. Using two-photon calcium imaging in mice running treadmill along with online manipulation, we identify robust responses granule cells. Cue cell stable, stimulus-specific, accompanied inhibition nearby neurons. This demonstrates existence "cue cells" addition to better characterized "place DG. We hypothesize supports parallel channels spatial non-spatial contribute distinctly downstream computations affect roles navigation episodic memory.

Язык: Английский

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Beyond hippocampus: Thalamic and prefrontal contributions to an evolving memory

Neuron, Год журнала: 2024, Номер 112(7), С. 1045 - 1059

Опубликована: Янв. 24, 2024

Язык: Английский

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Differential Relation between Neuronal and Behavioral Discrimination during Hippocampal Memory Encoding

Neuron, Год журнала: 2020, Номер 108(6), С. 1103 - 1112.e6

Опубликована: Окт. 16, 2020

How are distinct memories formed and used for behavior? To relate neuronal behavioral discrimination during memory formation, we use in vivo 2-photon Ca

Язык: Английский

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