Associations of sensory impairment and cognitive function in middle-aged and older Chinese population: The China Health and Retirement Longitudinal Study DOI Creative Commons
Xiaohuan Zhao, Yifan Zhou,

K. Wei

и другие.

Journal of Global Health, Год журнала: 2021, Номер 11

Опубликована: Дек. 18, 2021

Little is known about the associations between vision impairment, hearing and cognitive function. The aim of this study was to examine whether impairment were associated with a high risk for in middle-aged older Chinese adults.A total 13 914 adults from China Health Retirement Longitudinal Study (CHARLS) baseline selected analysis. Sensory assessed single self-report question, we categorized sensory into four groups: no dual impairment. Cognitive assessment covered memory, mental state, cognition, data obtained through questionnaire.Memory negatively (β = -0.043, 95% confidence interval (CI) -0.076, -0.043) -0.033, CI -0.049, -0.017); status -0.034, -0.018), -0.070, -0.086, -0.055), -0.054, -0.039); cognition -0.028, -0.044, -0.013), -0.074, -0.090, -0.059), -0.052, -0.067, -0.036), even after adjusting demographics, social economic factors, lifestyle behavior.Vision are status, elderly adults. There stronger negative cognitive-related indicators compared middle-aged.

Язык: Английский

Visual Impairment, Eye Diseases, and Dementia Risk: A Systematic Review and Meta-Analysis DOI
Elżbieta Kuźma, Thomas J. Littlejohns, Anthony P. Khawaja

и другие.

Journal of Alzheimer s Disease, Год журнала: 2021, Номер 83(3), С. 1073 - 1087

Опубликована: Авг. 13, 2021

Background: Visual impairment and eye diseases have been associated with dementia, though mixed findings often in cross-sectional studies. Objective: To identify prospective studies investigating associations between visual or common risk of all-cause dementia key subtypes. Methods: We searched Medline, PsycINFO, Embase from inception to January 2020. also conducted backward forward citation searches included set up alerts published after the search date. Random-effects meta-analysis was used combine adjusted estimates across Results: Thirty met our eligibility criteria. For impairment, pooled indicated an increased (37,705 participants, 3,415 cases, ratio [RR] = 1.38, 95% confidence interval [CI]: 1.19–1.59, I2 28.6%). Pooled suggested cataract (6,659 1,312 hazard [HR] 1.17, CI: 1.00–1.38, 0.0%) diabetic retinopathy (43,658 7,060 HR 1.34, 1.11–1.61, 63.9%), respectively. There no evidence association glaucoma (175,357 44,144 0.97, 0.90–1.04, 51.5%) age-related macular degeneration (7,800,692 > 2,559 1.15, 0.88–1.50, 91.0%) Conclusion: As cataract, are likelihood developing early diagnosis may help those at dementia. Given most causes treatable preventable, potential for prevention warrants further investigation.

Язык: Английский

Процитировано

55

Hearing Loss and Dementia: A Meta-Analysis of Prospective Cohort Studies DOI Creative Commons
Zheng Liang, Ao Li, Yuanyuan Xu

и другие.

Frontiers in Aging Neuroscience, Год журнала: 2021, Номер 13

Опубликована: Июль 8, 2021

Background: Consensus is lacking with regard to whether hearing loss an independent risk factor for dementia. We therefore conducted a meta-analysis clarify the relationship of and Methods: Prospective cohort studies investigating association between incidence dementia in community-derived population were included by searching electronic databases that PubMed, Embase, Cochrane's Library. A random-effects model was adopted combine results. Results: Fourteen cohorts including 726,900 participants analyzed. It shown independently associated [adjusted hazard ratio (HR): 1.59, 95% confidence interval (CI): 1.37 1.86, p < 0.001; I 2 = 86%]. Sensitivity analysis sequentially excluding any individual showed similar Subgroup according diagnostic methods loss, validation strategy dementia, follow-up duration, adjustment apolipoprotein E genotype also consistent results ( -values subgroup differences all > 0.05). Meta-analysis five connected higher Alzheimer's disease (adjusted HR: 2.24, CI: 1.32 3.79, 0.003; 2%). Conclusions: Hearing may increase adult population. Whether effective treatment could reduce should be explored future.

Язык: Английский

Процитировано

48

Age‐related hearing loss and cognitive decline: MRI and cellular evidence DOI
Zahra Jafari, Bryan Kolb, Majid H. Mohajerani

и другие.

Annals of the New York Academy of Sciences, Год журнала: 2021, Номер 1500(1), С. 17 - 33

Опубликована: Июнь 10, 2021

Extensive evidence supports the association between age-related hearing loss (ARHL) and cognitive decline. It is, however, unknown whether a causal relationship exists these two, or they both result from shared mechanisms. This paper intends to study this through comprehensive review of MRI findings as well cellular alterations. Our structural studies demonstrates that ARHL is independently linked accelerated atrophy total regional brain volumes reduced white matter integrity. Resting-state task-based fMRI on also show changes in spontaneous neural activity functional connectivity; alterations areas supporting auditory, language, cognitive, affective processing independent age, respectively. Although support decline, contribution potential mechanisms should be considered. In regard, indicates their role possible common underlying cognition. Considering existing evidence, no single hypothesis can explain link (i.e., sensory hypothesis) cause expected.

Язык: Английский

Процитировано

47

The effect of hearing aids on cognitive function: A systematic review DOI Creative Commons

Maxime E. Sanders,

Ellen Kant, A.L. Smit

и другие.

PLoS ONE, Год журнала: 2021, Номер 16(12), С. e0261207 - e0261207

Опубликована: Дек. 31, 2021

Rationale Dementia currently affects 50 million people globally with this expected to triple by 2050. Even though hearing loss is associated cognitive decline, the underlying mechanisms are not fully understood. Considering largest modifiable risk factor for developing dementia, it essential study effect of aids on function. Objective To systematically review existing literature examine evidence using intervention as a treatment deteriorating Design A search PubMed, Cochrane Library, Embase and grey was conducted revealing 3060 unique records between 1990–2020. Two reviewers independently selected longitudinal studies observing effects function in persons without dementia at onset study. Due heterogeneity data, meta-analysis could be performed. Outcomes described summary findings table portrayed diagrammatically. Results We identified 17 studies, spanning 30 years research 3526 participants. The included made use different tests. These tests were grouped into separate domains according DSM-V classification further analysis. most beneficial impact seems domain executive function, six showing improvement, two being inconclusive three demonstrating significant effect. Three five demonstrated improvement when screening brief mental status. least seen complex attention, eight no effects, compared one intervention. Conclusions Based systematic review, we conclude that there controversy about cognition. Additional through randomized clinical trials standardized assessment longer follow-up warranted elucidate relationship.

Язык: Английский

Процитировано

47

Associations of sensory impairment and cognitive function in middle-aged and older Chinese population: The China Health and Retirement Longitudinal Study DOI Creative Commons
Xiaohuan Zhao, Yifan Zhou,

K. Wei

и другие.

Journal of Global Health, Год журнала: 2021, Номер 11

Опубликована: Дек. 18, 2021

Little is known about the associations between vision impairment, hearing and cognitive function. The aim of this study was to examine whether impairment were associated with a high risk for in middle-aged older Chinese adults.A total 13 914 adults from China Health Retirement Longitudinal Study (CHARLS) baseline selected analysis. Sensory assessed single self-report question, we categorized sensory into four groups: no dual impairment. Cognitive assessment covered memory, mental state, cognition, data obtained through questionnaire.Memory negatively (β = -0.043, 95% confidence interval (CI) -0.076, -0.043) -0.033, CI -0.049, -0.017); status -0.034, -0.018), -0.070, -0.086, -0.055), -0.054, -0.039); cognition -0.028, -0.044, -0.013), -0.074, -0.090, -0.059), -0.052, -0.067, -0.036), even after adjusting demographics, social economic factors, lifestyle behavior.Vision are status, elderly adults. There stronger negative cognitive-related indicators compared middle-aged.

Язык: Английский

Процитировано

45