Coda DOI
Neil McNaughton,

Jeffrey A. Gray

Oxford University Press eBooks, Год журнала: 2024, Номер unknown, С. 515 - 518

Опубликована: Май 7, 2024

Abstract This coda provides a global conceptual summary of the data explosion last 20 years, our expansion to meet this, idea that personality can provide source unity, and role cognitive bias its interaction with disorder-specific systems sensitivities. The has necessitated addition 33 supporting published reviews original 10 Appendices. Our involved inclusion additive arousal/attention circuits previous subtractive decision ones; separation ‘reward’ into gain attraction components (similarly for ‘punishment’). theoretical treatment is not only expanded but intertwined psychiatric disorder; interlinking neural approaches emphasized. final conclusion that, as editions, this work in progress.

Язык: Английский

Ethology and anxiety DOI
Neil McNaughton,

Jeffrey A. Gray

Oxford University Press eBooks, Год журнала: 2024, Номер unknown, С. 47 - 60

Опубликована: Май 7, 2024

Abstract ‘Ethology and anxiety’ describes ethoexperimental ethopharmacological analysis of anxiety fear in semi-natural but experimentally controlled settings. A suite characteristic responses to an actual present predator can be characterized as (and are reduced by panicolytic drugs not anxiolytics). Conversely, a distinct uncertain The behaviours reflect two functional dimensions: defensive distance direction. key adaptive functions these suites, which define direction, appear permit withdrawal from danger, or cautious approach danger (to obtain good), respectively. Terminological problems, confirmation human studies, reasons for excluding rumination worry the discussed.

Язык: Английский

Процитировано

0

Memory and the septo-hippocampal system DOI
Neil McNaughton,

Jeffrey A. Gray

Oxford University Press eBooks, Год журнала: 2024, Номер unknown, С. 189 - 240

Опубликована: Май 7, 2024

Abstract ‘Memory and the septo-hippocampal system’ outlines five major myths about amnesia that have dogged analysis of function it critiques 10 theories ‘type’ memory supported by hippocampus: spatial, working, configural, recognition, semantic, contextual, relational, temporal buffer, intermediate, multiple trace transformation, contextual binding. In all cases there are non-conforming data and, in bulk cases, one can discern a role for interference. The suggest rather than amnesia, hippocampal damage produces catastrophic hypermnesia due to loss mechanism reverse effects interference once these occurred. This mechanism, Goal Inhibition System, not only accounts failure but also non-memorial changes result from damage. relation key aspects is outlined; hippocampus formation, consolidation, retrograde activation considered both wake sleep.

Язык: Английский

Процитировано

0

The treatment of anxiety and fear disorders DOI
Neil McNaughton,

Jeffrey A. Gray

Oxford University Press eBooks, Год журнала: 2024, Номер unknown, С. 497 - 514

Опубликована: Май 7, 2024

Abstract ‘The treatment of anxiety and fear disorders’ discusses behavioural cognitive methods (CBT) in detail, their impact on the brain, integration with drug therapies (pharmacotherapy) to achieve augmentation. It briefly summarizes pharmacotherapy, including drug-drug augmentation, based detailed reviews this earlier chapters (particularly Chapter 4). novel psychedelic apparent targeting neuroticism ameliorate neurotic disorders general; uses a double-hit (neuroticism + disorder-specific trait) model account for disorders, resistance, disorder sequencing, comorbidities—and relative therapeutic specificity slow action conventional drugs. We expect exciting future developments separate combined by psychedelics CBT methods.

Язык: Английский

Процитировано

0

Epigraph DOI
Neil McNaughton,

Jeffrey A. Gray

Опубликована: Май 7, 2024

Extract UN COUP DE DÉS JAMAIS N'ABOLIRA LAE HASARD Toute Pensée émet un Coup de Dés Stéphane Mallarmé

Процитировано

0

Coda DOI
Neil McNaughton,

Jeffrey A. Gray

Oxford University Press eBooks, Год журнала: 2024, Номер unknown, С. 515 - 518

Опубликована: Май 7, 2024

Abstract This coda provides a global conceptual summary of the data explosion last 20 years, our expansion to meet this, idea that personality can provide source unity, and role cognitive bias its interaction with disorder-specific systems sensitivities. The has necessitated addition 33 supporting published reviews original 10 Appendices. Our involved inclusion additive arousal/attention circuits previous subtractive decision ones; separation ‘reward’ into gain attraction components (similarly for ‘punishment’). theoretical treatment is not only expanded but intertwined psychiatric disorder; interlinking neural approaches emphasized. final conclusion that, as editions, this work in progress.

Язык: Английский

Процитировано

0