An adversarial collaboration to critically evaluate theories of consciousness

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2023, Номер unknown

Опубликована: Июнь 26, 2023

Summary Different theories explain how subjective experience arises from brain activity 1,2 . These have independently accrued evidence, yet, confirmation bias and dependence on design choices hamper progress in the field 3 Here, we present an open science adversarial collaboration which directly juxtaposes Integrated Information Theory (IIT) 4,5 Global Neuronal Workspace (GNWT) 6–10 , employing a theory-neutral consortium approach 11,12 We investigate neural correlates of content duration visual experience. The theory proponents developed preregistered experimental design, divergent predictions, expected outcomes, their interpretation 12 256 human subjects viewed suprathreshold stimuli for variable durations while was measured with functional magnetic resonance imaging, magnetoencephalography, electrocorticography. find information about conscious visual, ventro-temporal inferior frontal cortex, sustained responses occipital lateral temporal cortex reflecting stimulus duration, content-specific synchronization between early areas. results confirm some predictions IIT GNWT, substantially challenging both theories: IIT, lack within posterior contradicts claim that network connectivity specifies consciousness. GNWT is challenged by general ignition at offset limited representation certain dimensions prefrontal cortex. Beyond themselves, alternative to advance cognitive neuroscience through principled, theory-driven, collaborative effort. highlight challenges change people’s mind 13 need quantitative framework integrating evidence systematic testing building.

Язык: Английский

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Visual temporal attention from perception to computation

Nature Reviews Psychology, Год журнала: 2024, Номер 3(4), С. 261 - 274

Опубликована: Март 20, 2024

Язык: Английский

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Representing Variability

Опубликована: Фев. 28, 2024

The visual world is full of detail. This Element focuses on this variability in perception, asking how it affects performance tasks and the represented by human observers. authors highlight different methods for assessing representations suggest that understanding can be elusive when straightforward explicit are used, while more implicit may better suited to uncovering such processing. conclude far detail than previously thought aspect perception vital complexity consciousness.

Язык: Английский

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Centering cognitive neuroscience on task demands and generalization

Nature Neuroscience, Год журнала: 2024, Номер 27(9), С. 1656 - 1667

Опубликована: Июль 29, 2024

Язык: Английский

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Principles of intensive human neuroimaging

Trends in Neurosciences, Год журнала: 2024, Номер unknown

Опубликована: Окт. 1, 2024

Язык: Английский

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An adversarial collaboration to critically evaluate theories of consciousness

Research Square (Research Square), Год журнала: 2023, Номер unknown

Опубликована: Июнь 28, 2023

Abstract Different theories explain how subjective experience arises from brain activity1,2. These have independently accrued evidence, yet, confirmation bias and dependence on design choices hamper progress in the field3. Here, we present an open science adversarial collaboration which directly juxtaposes Integrated Information Theory (IIT)4,5 Global Neuronal Workspace (GNWT)6-10, employing a theory-neutral consortium approach11,12. We investigate neural correlates of content duration visual experience. The theory proponents developed preregistered experimental design, divergent predictions, expected outcomes, their interpretation12. 256 human subjects viewed suprathreshold stimuli for variable durations while activity was measured with functional magnetic resonance imaging, magnetoencephalography, electrocorticography. find information about conscious visual, ventro-temporal inferior frontal cortex, sustained responses occipital lateral temporal cortex reflecting stimulus duration, content-specific synchronization between early areas. results confirm some predictions IIT GNWT, substantially challenging both theories: IIT, lack within posterior contradicts claim that network connectivity specifies consciousness. GNWT is challenged by general ignition at offset limited representation certain dimensions prefrontal cortex. Beyond themselves, alternative approach to advance cognitive neuroscience through principled, theory-driven, collaborative effort. highlight challenges change people’s mind 13 need quantitative framework integrating evidence systematic testing building.

Язык: Английский

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Pre-frontal cortex guides dimension-reducing transformations in the occipito-ventral pathway for categorization behaviors

Current Biology, Год журнала: 2024, Номер 34(15), С. 3392 - 3404.e5

Опубликована: Июль 18, 2024

Highlights•Occipital cortex represents both task-relevant and irrelevant features before 120 ms•Only advance to the temporal region•During 121–150 ms, occipital representations reduce lower-dimensional manifolds•These manifolds then transform into from 161 350 msSummaryTo interpret our surroundings, brain uses a visual categorization process. Current theories models suggest that this process comprises hierarchy of different computations transforms complex, high-dimensional inputs (i.e., manifolds) in support multiple behaviors. Here, we tested hypothesis by analyzing these transformations reflected dynamic MEG source activity while individual participants actively categorized same stimuli according tasks: face expression, gender, pedestrian vehicle type. Results reveal three transformation stages guided pre-frontal cortex. At stage 1 (high-dimensional, 50–120 ms), sources represent task-irrelevant stimulus features; higher ventral/dorsal regions, whereas halt at occipital-temporal junction. 2 (121–150 feature manifolds, which underlying behavior over 3 (161–350 ms). Our findings shed light on how brain's network mechanisms specific behaviors.Graphical abstract

Язык: Английский

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Advancing visual neuroscience: expanding boundaries from bench to bedside

Visual Neuroscience, Год журнала: 2025, Номер 42(1), С. 0 - 0

Опубликована: Янв. 1, 2025

Язык: Английский

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Spatial Frequency Maps in Human Visual Cortex: A Replication and Extension

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

In a step toward developing model of human primary visual cortex, recent study developed spatial frequency tuning in V1 (Broderick, Simoncelli, & Winawer, 2022). The is compact, using just 9 parameters to predict BOLD response amplitude for locations across all as function stimulus orientation and frequency. Here we replicated this analysis new dataset, the 'nsdsynthetic' supplement Natural Scenes Dataset (Allen et al., 2022), order assess generalization parameters. Furthermore, extended analyses extrastriate maps V2 V3. For each retinotopic map 8 NSD subjects, fit parameter model. Despite many experimental differences between original study, including size, design, MR field strength, there was good agreement most dependence preferred on eccentricity similar Broderick al. Moreover, effect absolute similar: higher horizontal cardinal orientations compared vertical oblique both studies. extension revealed that biggest change bandwidth: bandwidth increased by 70% from 100% V3, paralleling known increases receptive size. Together, results show robust reproducibility fMRI experiments, bring us closer systematic characterization encoding system.

Язык: Английский

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Comparative fMRI reveals differences in the functional organization of the visual cortex for animacy perception in dogs and humans

Опубликована: Март 11, 2025

The animate-inanimate category distinction is one of the general organizing principles in primate high-level visual cortex. Much less known about cortical representations animacy non-primate mammals with a different evolutionary trajectory capacities. To compare functional organization underlying perception to species, here we performed an fMRI study dogs and humans, investigating how structures neural responses cortex two species. Univariate analyses identified animate-sensitive bilateral occipital temporal regions, non-overlapping early areas, both Multivariate tests confirmed categorical animate stimuli these regions. Regions sensitive stimulus classes (dog, human, cat) overlapped dog than human brains. Together, findings reveal that importance reflected higher-level cortex, also beyond primates. But key species difference, for are concentrated humans suggests certain support primates may not play similarly important role other mammals.

Язык: Английский

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