bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2023, Номер unknown
Опубликована: Дек. 11, 2023
Abstract Decision-making is a cognitive process, in which participants need to attend relevant information and ignore the irrelevant information. Previous studies have described set of cortical areas important for attention. It unclear whether subcortical also serve role. The subthalamic nucleus (STN), part basal ganglia, traditionally considered critical node cortico-basal ganglia-thalamus-cortico network. Given location STN its widespread connections with brain regions, plays an role motor non-motor processing. We would like know if related fluctuations attentional task performance, how interacts prefrontal regions during process. examined neural activities within covaried lapses attention (defined as behavior error). found that decreased were associated sustained By examining connectivity across various sub-regions cortex (PFC), we was Our results indicated attention, STN-PFC circuit supported this Significance Statement Attention core internal state variable governs allocation limited resources depending on demands processes. If area, fluctuations, interacted process remains unclear. In study, STN, between both These findings
Язык: Английский