Qualitative and quantitative educational disparities and brain signatures in healthy aging and dementia across global settings

EClinicalMedicine, Год журнала: 2025, Номер 82, С. 103187 - 103187

Опубликована: Апрель 1, 2025

While education is crucial for brain health, evidence mainly relies on individual measures of years (YoE), neglecting quality (EQ). The effect YoE and EQ aging dementia has not been compared. We conducted a cross-sectional assessment the health in 7533 subjects from 20 countries, including healthy controls (HCs), Alzheimer's disease (AD), frontotemporal lobar degeneration (FTLD). was based country-level indicators provided by programme international student (PISA). After applying neuroimage harmonization, we examined its effect, along with YoE, gray matter volume functional connectivity. Regression models were adjusted age, sex, cognition, controlling multiple comparisons. influence image assessed through sensitivity analysis. Data collection between June 1 October 30, 2024. Less associated alterations across groups. However, had stronger influence, targeting critical areas each condition. At whole-brain level, influenced (HCs: Δmean = 2·0 [1·9-2·0] × 10-2, p < 10-5; AD: 0·1 [-0·0 to 0·3] 0·18; FTLD: 3·5 [3·0-4·0] all 95% confidence intervals) networks 13·5 [13·2-13·7] 5·9 [5·2-6·7] 13·2 [11·2-13·7] 10-5) 1·3 7·0 times more than YoE. These effects remain robust despite variations income socioeconomic factors at country levels. results support need incorporate into studying improving underscoring importance measures. Multi-partner consortium expand research Latin America (ReDLat).

Язык: Английский

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Biological imprint of education and rights‐based brain capital

Alzheimer s & Dementia, Год журнала: 2025, Номер 21(4)

Опубликована: Апрель 1, 2025

Язык: Английский

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Ultrafine particles and late-life cognitive function: Influence of stationary mobile monitoring design on health inferences

Environmental Pollution, Год журнала: 2025, Номер unknown, С. 126222 - 126222

Опубликована: Апрель 1, 2025

Язык: Английский

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Impacts to Mental and Brain Health on Irregular and Deported Colombian Migrants: Implications for Policy and Practice

Опубликована: Янв. 1, 2025

Язык: Английский

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