Journal of Agricultural and Food Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 31, 2024
Flavonoids
are
naturally
occurring
compounds
found
in
fruits,
vegetables,
and
other
plant-based
foods,
they
known
for
their
health
benefits,
such
as
UV
protection,
antioxidant,
anti-inflammatory,
antiproliferative
properties.
This
study
investigates
whether
flavonoids,
quercetin
2,3-dehydrosilybin,
can
act
photoactivatable
carbon
monoxide
(CO)-releasing
molecules
under
physiological
conditions.
CO
has
been
recently
recognized
an
important
signaling
molecule.
Here,
we
show
that
upon
direct
irradiation,
was
released
from
both
flavonoids
PBS
with
chemical
yields
of
up
to
0.23
equiv,
which
increased
almost
unity
by
sensitized
photooxygenation
involving
singlet
oxygen.
Photoreleased
reduced
cellular
toxicity
caused
high
flavonol
concentrations,
partially
restored
mitochondrial
respiration,
superoxide
production
induced
rotenone
levels,
influenced
the
G0/G1
G2/M
phases
cell
cycle,
showing
effects.
The
findings
highlight
potential
2,3-dehydrosilybin
CO-photoreleasing
chemopreventive
therapeutic
implications
human
pathology
suggest
possible
roles
plant
biology.
Physiologia Plantarum,
Год журнала:
2024,
Номер
176(6)
Опубликована: Ноя. 1, 2024
Abstract
Nitric
oxide
(NO)
and
hydrogen
sulphide
(H
2
S)
play
important
roles
in
plant
growth,
development
environmental
adaptation.
Currently,
there
is
few
information
on
the
mechanism
by
which
H
S
may
be
involved
NO‐induced
salt
tolerance.
In
this
study,
cucumber
was
used
to
investigate
role
of
NO
their
relationship
under
stress.
The
results
showed
that
donor
sodium
hydrosulfide
(NaHS)
nitroprusside
(SNP)
significantly
promoted
growth
seedlings
However,
hypotaurine
(HT,
an
scavenger)
inhibited
positive
effects
SNP
Meanwhile,
treatment
increased
content
endogenous
S,
activity
synthesis‐related
enzymes
LCD,
DCD,
CAS,
expression
genes
(
CsLCD
CsDCD
).
addition,
tolerance
largely
eliminated
after
silencing
/
,
while
overexpression
enhanced
It
further
found
lines,
but
it
had
no
effect
lines.
Therefore,
might
enhance
upregulating
gene
.
Journal of Agricultural and Food Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 31, 2024
Flavonoids
are
naturally
occurring
compounds
found
in
fruits,
vegetables,
and
other
plant-based
foods,
they
known
for
their
health
benefits,
such
as
UV
protection,
antioxidant,
anti-inflammatory,
antiproliferative
properties.
This
study
investigates
whether
flavonoids,
quercetin
2,3-dehydrosilybin,
can
act
photoactivatable
carbon
monoxide
(CO)-releasing
molecules
under
physiological
conditions.
CO
has
been
recently
recognized
an
important
signaling
molecule.
Here,
we
show
that
upon
direct
irradiation,
was
released
from
both
flavonoids
PBS
with
chemical
yields
of
up
to
0.23
equiv,
which
increased
almost
unity
by
sensitized
photooxygenation
involving
singlet
oxygen.
Photoreleased
reduced
cellular
toxicity
caused
high
flavonol
concentrations,
partially
restored
mitochondrial
respiration,
superoxide
production
induced
rotenone
levels,
influenced
the
G0/G1
G2/M
phases
cell
cycle,
showing
effects.
The
findings
highlight
potential
2,3-dehydrosilybin
CO-photoreleasing
chemopreventive
therapeutic
implications
human
pathology
suggest
possible
roles
plant
biology.
