Associations between systemic immune-inflammatory index and visceral adipose tissue area: results of a national survey
Yayun Liao,
Kejian Zhou,
Baoquan Lin
и другие.
Frontiers in Nutrition,
Год журнала:
2025,
Номер
11
Опубликована: Янв. 16, 2025
Global
health
issues
related
to
obesity
are
growing.
Visceral
adipose
tissue
(VAT)
significantly
contributes
complications
associated
with
obesity.
Reducing
accumulation
can
improves
inflammation.
However,
it
is
still
unknown
how
the
systemic
immune-inflammation
index
(SII)
and
VAT
area
related.
With
help
of
multivariate
linear
regression
smooth
curve
fitting,
relationship
between
SII
was
explored
data
from
2013
2014
National
Health
Nutrition
Examination
Survey
(NHANES).
Analyzing
subgroups
testing
for
interaction
were
used
investigate
whether
accurate
across
demographics.
From
20
59
years
age,
3,290
individuals
observed
have
a
positive
correlation
area.
In
accordance
fully
adjusted
model,
increased
by
9.34
cm2
every
unit
increase
in
log
[β
=
9.34,
95%
CI
(4.02,
14.67)].
highest
quartile
SII,
5.46
5.46,
(2.21,
8.71)]
higher
than
that
lowest
quartile.
Additionally,
population
overweight
or
obese
showed
stronger
correlation.
has
US
adults.
may
be
valuable
clinical
applications
evaluate
severity
Язык: Английский
Association between systemic immune-inflammation index and central obesity in pediatric populations: a cross-sectional and cohort study
Frontiers in Immunology,
Год журнала:
2025,
Номер
16
Опубликована: Фев. 19, 2025
Central
obesity
in
children
represents
a
significant
public
health
concern
due
to
its
strong
association
with
an
elevated
risk
of
metabolic
and
cardiovascular
disorders.
The
systemic
immune
inflammation
index
(SII)
has
been
implicated
the
pathophysiology
obesity-related
chronic
inflammation.
Despite
potential
relevance,
specific
relationship
between
central
SII
pediatric
population
remains
insufficiently
explored.
objective
this
study
was
examine
obesity,
particular
focus
on
as
predictor
means
preventing
at
early
stage
life.
Waist-to-height
ratio
(WHtR),
subcutaneous
fat,
visceral
fat
were
employed
proxies.
defined
according
WHtR
cutoff
value
0.46.
implications
examined
sample
4,730
individuals
2021
validated
through
prospective
involving
1,425
subjects
2023.
Cross-sectional
associations
using
binomial
logistic
regression
models
generalized
linear
models.
restricted
cubic
spline
used
explore
non-linear
indicators.
In
study,
we
modified
Poisson
model
investigate
causal
obesity.
Cross-sectionally,
adolescents
highest
quartile
levels
exhibited
greatest
for
obesity(OR=3.07,
95%
CI:2.45~3.87)
when
compared
those
lowest
quartile.
Subgroup
analyses
showed
that
higher
associated
Longitudinally,
found
have
developing
(RR=1.83,
CI:1.18~2.83)
over
time.
Язык: Английский
Neutrophils as mediators of the association between lipid accumulation product and kidney stones, but not for recurrent kidney stones in US adults
Urolithiasis,
Год журнала:
2025,
Номер
53(1)
Опубликована: Март 31, 2025
Язык: Английский
Weight-adjusted waist index and its relationship with systemic inflammatory Index and metabolic indices in overweight and obese individuals: A cross-sectional study
Science Progress,
Год журнала:
2025,
Номер
108(2)
Опубликована: Апрель 1, 2025
Background
Obesity-
characterized
by
excessive
adiposity-
is
associated
with
various
comorbidities,
including
metabolic,
cardiovascular,
and
liver
diseases.
Chronic
low-grade
inflammation
a
key
factor
in
complications
obesity.
This
study
aimed
to
investigate
the
associations
between
systemic
inflammatory
indices
(SIIs)
weight-adjusted
waist
index
(WWI),
alongside
metabolic
function
biomarkers
overweight
obese
individuals.
Method
cross-sectional
included
350
or
participants
(body
mass
(BMI)
≥
25
kg/m
2
)
from
both
genders.
Weight,
height,
waist,
hip,
neck
circumferences
were
measured
BMI,
WWI,
ratios
of
height
(WHtR)
hip
(WHR)
estimated.
Fasting
blood
samples
taken
assess
SII
as
well
parameters.
Results
In
this
study,
males
had
significantly
higher
weight
WC
compared
females,
whereas
mean
level
WWI
(p
<
0001)
WHtR
=
0.01)
women
greater
than
men.
A
significant
correlation
was
observed
(r
0.113,
p
0.039),
other
HbA1c
levels
−0.117,
0.033)
monocyte-to-lymphocyte
ratio
(MLR),
fasting
sugar
(FBS)
neutrophil-to-lymphocyte
NLR
0.110,
0.041).
quartiles
showed
differences
aspartate
aminotransferase
AST
0.001),
variations
MLR
also
−0.112,
0.043).
Conclusion
Our
results
reveal
strong
correlations
markers,
SII,
MLR,
PLR,
important
obesity
measures,
parameters
individuals
Язык: Английский