Cervical cancer: Novel treatment strategies offer renewed optimism
Gangotri yadav,
Ganga Srinivasan,
Ashish Jain
и другие.
Pathology - Research and Practice,
Год журнала:
2024,
Номер
254, С. 155136 - 155136
Опубликована: Янв. 15, 2024
Язык: Английский
Improving Strawberry Shelf Life Using Chitosan and Zinc Oxide Nanoparticles from Ginger-Garlic Extracts
Applied Food Research,
Год журнала:
2025,
Номер
unknown, С. 100765 - 100765
Опубликована: Фев. 1, 2025
Язык: Английский
Hydroxyapatite modified poly(acrylic acid)/polyethylene glycol sustainable drug delivery nanocomposite prepared via double emulsion with bitter almond oil
Sustainable Chemistry and Pharmacy,
Год журнала:
2024,
Номер
38, С. 101497 - 101497
Опубликована: Фев. 21, 2024
A
sustainable
hydrogel-based
drug
delivery
system
for
pH-sensitive
of
doxorubicin
(DOX)
as
a
model
has
been
developed
the
first
time
to
address
some
complications
chemotherapy.
The
biobased
nanocomposite
comprising
hydroxyapatite
(HAP)
nanoparticles
loaded
in
biodegradable
poly(acrylic
acid)
(PAA)/polyethylene
glycol
(PEG)
hydrogel
network
was
prepared
via
double
emulsion
method
using
bitter
almond
oil
and
span
80
surfactant.
Double
emulsions
can
expand
release
drugs
longer
period
well
increase
their
bioavailability
tumor
tissues.
Multiple
analyses
were
conducted
assess
structure
nanocarriers
therapeutic
efficiency.
XRD
FTIR
corroborated
successful
synthesis
gave
insight
into
crystalline
nature
molecular
interactions
between
components.
DLS
revealed
monodispersity
nanocarriers,
with
an
average
size
418
nm.
TEM
SEM
showed
spherical
porous
morphology
zeta
potential
measurements
indicated
surface
charge
−34.5
mV,
thus
corroborating
excellent
stability
suitability
long
storage.
loading
entrapment
efficiencies
(46%
87.5%,
respectively)
higher
than
those
reported
previously
similar
nanocarriers.
An
effective
sustained
profile
observed
at
pH
5.4.
MMT
assay
flow
cytometric
that
satisfactory
cytotoxicity
compared
free
DOX.
Язык: Английский
Chitosan films developed using all-natural resource for fruit preservation and the impact of lemon Peel extract mediated nickel ferrite nanoparticles on films' physical and barrier properties
Food Chemistry,
Год журнала:
2025,
Номер
482, С. 144068 - 144068
Опубликована: Март 30, 2025
Язык: Английский
Mapping the formation of gemcitabine-immunoglobulin nanoparticles and the subsequent activity against pancreatic cancer cells
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
304, С. 140729 - 140729
Опубликована: Фев. 5, 2025
Язык: Английский
Construction and Characterization of 5,6-O-Isopropylidene-L-Ascorbic Acid-Loaded Silver and Manganese Dioxide Nanoparticles: Cytotoxicity Study, Antibacterial, and Antioxidant Activities
Materials Chemistry and Physics,
Год журнала:
2025,
Номер
unknown, С. 130517 - 130517
Опубликована: Фев. 1, 2025
Язык: Английский
Environmentally Sustainable and Green Polymeric Method for Chitosan (CH) Film Synthesis Using Natural Acids and Impact of Zinc Ferrite Nanoparticles (NPs) on Water Solubility (WS) and Physical Properties
Polymers,
Год журнала:
2024,
Номер
16(24), С. 3466 - 3466
Опубликована: Дек. 12, 2024
Currently,
there
is
a
rush
to
develop
green
polymeric
films
such
as
biodegradable
chitosan
(CH)
control
and
prevent
plastic
pollution
from
degrading
the
environment.
This
study
reports
novel
sustainable
approach
development
of
CH
using
lemon
juice
(LJ)
peel
extract
(LPE),
latter
dilute
LJ.
The
LPE
was
also
utilized
for
synthesis
ZnFe2O4
nanoparticles
(NPs),
adding
this
work’s
novelty.
crystalline
size
NPs
computed
be
~16
nm.
introduction
1%
2%
improved
not
only
mechanical
properties
films,
but
their
barrier
water
solubility
(WS).
tensile
strength
increased
0.641
MPa
0.835
when
were
incorporated,
which
almost
1.30
times
greater;
enhanced
surface
by
2.66
times,
demonstrated
puncture
strength.
occupied
vacant
spaces
capabilities
film
reducing
vapor
permeability
(WVP)
value
8.752
±
0.015
bare
6.299
0.009
NP-containing
films.
Overall,
boosted
offers
promising
method
developing
sustainable,
eco-friendly,
potential
packaging
medical
applications
contribute
circular
economic
efforts.
Язык: Английский
Harnessing Bio-Waste for Biomedical Applications: A New Horizon in Sustainable Healthcare
European Journal of Medicinal Chemistry Reports,
Год журнала:
2024,
Номер
unknown, С. 100234 - 100234
Опубликована: Окт. 1, 2024
Язык: Английский
Network Pharmacology Approaches Used to Identify Therapeutic Molecules for Chronic Venous Disease Based on Potential miRNA Biomarkers
Journal of Xenobiotics,
Год журнала:
2024,
Номер
14(4), С. 1519 - 1540
Опубликована: Окт. 15, 2024
Chronic
venous
disease
(CVD)
is
a
prevalent
condition
in
adults,
significantly
affecting
the
global
elderly
population,
with
higher
incidence
women
than
men.
The
modulation
of
gene
expression
through
microRNA
(miRNA)
partly
regulated
development
cardiovascular
(CVD).
Previous
research
identified
functional
analysis
seven
genes
(CDS2,
HDAC5,
PPP6R2,
PRRC2B,
TBC1D22A,
WNK1,
and
PABPC3)
as
targets
miRNAs
related
to
CVD.
In
this
context,
emerge
essential
candidates
for
CVD
diagnosis,
representing
novel
molecular
biological
knowledge.
This
work
aims
identify,
by
network
analysis,
involved
potential
biomarkers,
either
interacting
small
molecules
such
toxins
pollutants
or
searching
new
drugs.
Our
study
shows
an
updated
landscape
signaling
pathways
involving
pathology.
latest
includes
data
found
experimental
tests
uses
predictions
propose
both
biomarkers
develop
diagnostic
therapeutic
methods
early
detection
clinical
setting.
addition,
our
pharmacological
has,
first
time,
shown
how
use
these
find
that
may
regulate
them.
Between
research,
toxins,
pollutants,
drugs
showed
outstanding
interactions
miRNAs.
One
them,
hesperidin,
widely
prescribed
drug
treating
modulating
associated
CVD,
was
used
reference
interact
Among
exhibit
same
miRNA
profile
include
desoximetasone,
curcumin,
flurandrenolide,
trifluridine,
fludrocortisone,
diflorasone,
gemcitabine,
floxuridine,
reversine.
Further
investigation
improve
treatment
disease.
Additionally,
supporting
diagnosing
predicting
crucial.
Язык: Английский