Active induction: a promising strategy for enhancing the bioactivity of lactic acid bacteria DOI
Sisi Chen, Keke Suo,

Qiaozhen Kang

и другие.

Critical Reviews in Food Science and Nutrition, Год журнала: 2025, Номер unknown, С. 1 - 16

Опубликована: Март 20, 2025

Lactic acid bacteria (LAB), as key probiotic, play crucial roles in maintaining human health. However, their survival and functionality diverse habitats depend on ability to sense respond environmental stresses. Notably, active induction has emerged a promising strategy for regulating the biological activity of LAB, potentially enhancing health benefits. Therefore, this review summarizes beneficial effects induction, including acid, bile, oxidation, ethanol, heat, cold, radiation functional activities LAB. In addition, omics methods, silico analysis, gene editing technologies have greatly facilitated profound exploration stress regulatory network thereby aiding identification components adaptors. Through these advancements, LAB provide benefits by stress-related genes proteins, well inducing bioactive metabolite production. As result, they could enhance tolerance, cross-protection, intestinal colonization, adhesion properties, antialcohol liver protection vitro or vivo. This study highlights potential strategies role food applications.

Язык: Английский

Active induction: a promising strategy for enhancing the bioactivity of lactic acid bacteria DOI
Sisi Chen, Keke Suo,

Qiaozhen Kang

и другие.

Critical Reviews in Food Science and Nutrition, Год журнала: 2025, Номер unknown, С. 1 - 16

Опубликована: Март 20, 2025

Lactic acid bacteria (LAB), as key probiotic, play crucial roles in maintaining human health. However, their survival and functionality diverse habitats depend on ability to sense respond environmental stresses. Notably, active induction has emerged a promising strategy for regulating the biological activity of LAB, potentially enhancing health benefits. Therefore, this review summarizes beneficial effects induction, including acid, bile, oxidation, ethanol, heat, cold, radiation functional activities LAB. In addition, omics methods, silico analysis, gene editing technologies have greatly facilitated profound exploration stress regulatory network thereby aiding identification components adaptors. Through these advancements, LAB provide benefits by stress-related genes proteins, well inducing bioactive metabolite production. As result, they could enhance tolerance, cross-protection, intestinal colonization, adhesion properties, antialcohol liver protection vitro or vivo. This study highlights potential strategies role food applications.

Язык: Английский

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