Update on Autoimmune Pancreatitis and IgG4‐Related Disease

United European Gastroenterology Journal, Год журнала: 2024, Номер unknown

Опубликована: Дек. 21, 2024

ABSTRACT Autoimmune pancreatitis is an increasingly recognized inflammatory type of subacute pancreatitis; two subtypes autoimmune have been identified so far: the “lymphoplasmacytic” 1 variant and “neutrophilic” 2 variant. Type represents most common manifestation IgG4‐related disease, a fibro‐inflammatory disorder characterized by elevated IgG4 levels in serum affected tissues. pancreas‐specific that frequently occurs context bowel diseases. Due to complexity both diseases, comprehensive work up with imaging, laboratory, histological studies required achieve diagnosis rule out malignancies. Glucocorticoids represent cornerstone treatment, often supported other immunosuppressive drugs case steroid intolerance or aggressive disease. Maintenance treatment employed because higher relapse rate compared pancreatitis. In this review, we summarize key concept pancreatitis, delve into differential between subtypes, cover recent relevant research findings pressing unmet needs.

Язык: Английский

A Case with Multiple Pathologies in the Pancreatic Head

Biomedicines, Год журнала: 2024, Номер 12(8), С. 1762 - 1762

Опубликована: Авг. 5, 2024

Autoimmune pancreatitis (AIP) type 1, paraduodenal (groove) pancreatitis, and follicular are rare clinical entities whose diagnosis may be challenging, given the potential imaging overlap with pancreatic cancer.

Язык: Английский