Environmental Aetiology of Autism and Subsequent Interventional Management

Journal of Environmental Science, Год журнала: 2022, Номер 0(0), С. 0 - 0

Опубликована: Ноя. 8, 2022

Background: Autism spectrum disorder (ASD) is a complicated disorder.Up to 50% of its variance could be related environmental factors.Aim: Environmental risk factors for ASD were studied among cases and controls.Additionally, the effects some targeted interventional approaches on severity language abilities compared.Methodology: This study was conducted 61 autistic children (3-12 years) who visited outpatient clinic "Children with ASD" from September 2021 February 2022.They subjected Childhood Rating Scale, Arabic Preschool Language Scale.The control subjects (N=62) selected volunteers.A questionnaire designed studying factors.Children then divided into two groups: Group (N=30) received phoniatric therapy; b (N=31) therapy dietary supplementation.After 3 months, both groups reassessed.Results: Risk such as maternal exposure disinfectants cleaners (78.7%), moderate (39.3 %) paternal (47.5 educational level, pregnancy in Summer (19.6%), delivery Spring (19.6%) prematurity (91.8%), showed significant statistical difference between (P=0.01,0.00,0.04,0.00respectively).Following intervention,

Язык: Английский

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Exploitation of bis(tert‐butylaminomethyl)pyridine as a chemical modifier in a carbon paste electrode for sensitive and selective potentiometric determination of Al³⁺ ion in pharmaceutical and water samples

Electroanalysis, Год журнала: 2023, Номер 35(12)

Опубликована: Сен. 21, 2023

Abstract The fabrication of a novel bis(tert‐butylaminomethyl)pyridine pincer ligand‐based ionophore in carbon paste electrode (CPE) matrix for Al 3+ ions was investigated. With Nernstian slope 20.05±0.27 mV decade −1 and low detection limit 1.0×10 −7 mol L , the demonstrated an excellent response ion over broad concentration range from to . formula graphite that produced greatest results 69.44 % graphite, 27.78 tricresyl phosphate (TCP) binder, 2.78 ionophore. This worked well with aqueous solutions had pH values between 2.5 5.5. It may be used at least 4 months without any detectable potentials digression has reasonably quick time (5 s). suggested graphitic strong selectivity other cations. isothermal coefficient electrode, which determined 0.2884×10 −3 V °C calculated by looking impact test solution temperature on potentials. also applied non‐aqueous media aqueous‐non‐aqueous volume ratio up 75 : 25. data acquired using this CPE as indicator potentiometric measurement several actual samples equivalent attained atomic absorption spectroscopy (AAS).

Язык: Английский

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Exposição ao praguicida glifosato e a ocorrência do transtorno do espectro autista: existe associação?

Saúde e Pesquisa, Год журнала: 2023, Номер 16(1), С. 1 - 16

Опубликована: Март 31, 2023

O presente estudo teve como objetivo estudar a associação entre exposição ao glifosato e ocorrência do Transtorno Espectro Autista (TEA). Trata-se de um documental com busca dados acerca da prevalência TEA (Centers of Disease Control and Prevention) levantamento para verificar o princípio ativo praguicida mais usado no Brasil (Instituto Brasileiro Meio Ambiente dos Recursos Naturais Renováveis) mundo (United States Evironmental Prevention Agency). Os resultados mostraram que aumentou longo anos. Do mesmo modo, uso compra praguicidas também aumentaram, sendo usado. Ainda os apontem existência uma relação autismo, são necessários estudos afirmar potencial neurotóxico sua nascimento crianças autistas.

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Take Your Shots? Parents’ Fear of Adverse Effects of Vaccines

Опубликована: Янв. 1, 2023

Parents' fear of adverse effects childhood vaccines is a major contributor to vaccine hesitancy in high-income countries. Autism, autoimmune disease, and weakening or "overwhelming" the immune system are among specific mentioned by parents. Based on large, population-based studies, risk autism not increased children who receive measles (or measles-mumps-rubella, MMR) other vaccines. Despite large number currently recommended, fully vaccinated at lower overall death no infections caused bacteria viruses unrelated those against. Autoimmune diseases like type 1 diabetes, Crohn's ulcerative colitis, rheumatic diseases, multiple sclerosis vaccination. Multisystem inflammatory disease myocarditis do occur COVID-19 vaccine, but much rate than unvaccinated.

Язык: Английский

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The Zinc-Copper Connection In Autism Spectrum Disorder: Pioneering Work Of Dr. Geir Bjørklund

Ars medica tomitana, Год журнала: 2023, Номер 29(4), С. 245 - 257

Опубликована: Ноя. 1, 2023

Abstract This interview delves into the relationship between zinc (Zn) and copper (Cu) in autism spectrum disorder (ASD), featuring insights from Dr. Geir Bjørklund, MD, a Norwegian researcher. Collaborative studies conducted across diverse countries, including China, Slovenia, Romania, Russia, Brazil, Egypt, consistently reveal altered Zn Cu levels individuals with ASD. These findings suggest potential correlation elevated increased severity of ASD symptoms. Bjørklund emphasizes multifaceted dynamics metallothioneins (MTs), essential proteins for metal binding detoxification, their association deficiency individuals. The illuminates balance within GABAergic system, implicating these trace elements synaptic modulation broader neurobiological functions. Future research directions proposed by encompass exploring multiple biological mediums accurate element assessment, investigating interactions different elements, factors influencing various tissues. significance supplementation treating ASD, implications MT dysfunction, importance dual monitoring during therapy are thoroughly discussed. conclusion expresses gratitude Bjørklund’s invaluable contributions to comprehending role highlighting global relevance his need comprehensive approach understanding this complex neurodevelopmental disorder.

Язык: Английский

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