Environmental
access
to
exercise
opportunities
plays
a
crucial
role
in
determining
the
level
of
physical
activity
within
population.
However,
it
is
unclear
how
environmental
factors
contribute
disparities
and
health
outcomes.
We
explored
associations
between
county-level
cardiovascular
disease
(CVD)
mortality
across
US
counties.
conducted
an
ecological
analysis
using
aggregated
data
from
two
primary
sources:
County
Health
Rankings
Roadmaps
CDC
WONDER
data.
compared
age-adjusted
CVD
quartiles
inactivity.
Stratification
was
performed
based
on
age,
sex,
race,
urbanization
variables.
The
rate
ratio
(RR)
for
also
calculated
generalized
linear
models.
observed
significant
variations
different
levels
inactivity,
which
consistent
all
demographic
subgroups
(P
<
0.001).
Access
significantly
associated
with
reduced
risk
(RR
=
0.93
[0.91-0.95]),
association
most
pronounced
acute
myocardial
infarction
(AMI)
(RR,
0.80
[0.76-0.85]).
inactivity
increased
1.16
[1.14-1.17]),
especially
ischemic
heart
(IHD)
1.35
[1.31-1.38])
AMI
1.32
[1.25-1.38]).
All
demonstrated
similar
benefits
reducing
by
improving
indicators
activity.
Counties
have
potential
make
strides
their
populations
enhancing
context
urbanization.
Engaging
in
habitual
resistance
exercise
training
(RET;
also
known
as
strength
training)
causes
systemic
health
effects
beyond
those
caused
by
aerobic/endurance
alone.
Despite
the
resoundingly
favorable
effect
of
RET
on
measures
cardiovascular
disease
risk,
controversy
still
exists
regarding
vascular
this
modality
largely
because
some
studies
find
increases
large
artery
stiffness
and
central
pulsatile
hemodynamics
with
RET.
In
two-part
series,
we
examine
acute
(RE)
hemodynamics.
We
perform
a
historical
overview
seminal/classic
report
key
findings
that
have
shaped
field.
provide
personal
commentary
potential
implications
related
to
RE
For
part
one
detailed
analysis
hemodynamic
signature
produced
during
discuss
sub-acute
short-term
modulation
Acute
elicits
marked
("extreme")
elevations
arterial
pressure,
mediated
primarily
intrathoracic
pressure
(ITP).
Vascular
compression
from
muscular
contraction
contributes
afterload
via
increased
wave
reflections.
However,
result
higher
ITP
associated
breath
holds
(Valsalva
maneuver)
high
relative
efforts
(>80%),
change
across
aortic
wall
(transmural
pressure)
is
less
than
intra-arterial
pressure.
The
pressures
heavy
weight
lifting
exercises
are
positive
swings
Valsalva
maneuver
resistance.
oscillations
lead
stress
within
likely
contribute
over
subsequent
hour.
Journal of Physical Activity and Health,
Год журнала:
2025,
Номер
unknown, С. 1 - 9
Опубликована: Янв. 1, 2025
Background
:
Type-specific
physical
activity
(PA)
may
be
associated
with
different
risks
of
ischemic
heart
disease
(IHD),
but
few
large
studies
have
examined
this.
This
study
aimed
to
assess
the
incidence
and
dose–response
relationships
between
total
PA
4
types
IHD
risk
in
Chinese
adults.
Methods
The
prospective
China
Kadoorie
Biobank
enrolled
35,508
adults
from
Qingdao
2004
2008,
including
33,342
IHD-free
participants
this
analysis.
was
collected
through
a
self-report
questionnaire,
calculating
metabolic
equivalents
task-hours
per
day
based
on
duration
frequency.
Cox
regression
analysis
used
association
risk.
Results
During
median
9.2
years
follow-up,
2712
incident
cases
were
recorded.
Total,
occupational,
commuting,
leisure-time
PAs
inversely
Compared
bottom
quintiles
PA,
top
occupational
commuting
had
43%
(hazard
ratio
[HR]
=
0.57;
95%
CI,
0.49–0.66),
38%
(HR
0.62;
0.50–0.75),
0.44–0.87),
21%
0.79;
0.67–0.95)
lower
risk,
respectively.
A
negative
household
found
only
males
0.83;
0.70–0.98).
restricted
cubic
spline
revealed
linear
relationship
(
P
for
nonlinear
.5687).
Conclusion
Among
adults,
higher
total,
significantly
IHD,
increased
could
reduce
males.
BMC Cardiovascular Disorders,
Год журнала:
2025,
Номер
25(1)
Опубликована: Фев. 20, 2025
Frailty
and
inflammation
may
increase
the
risk
of
cardiovascular
disease
(CVD),
but
their
interacting
joint
effects
on
CVDs
remain
unclear.
To
explore
interaction
frailty
role
in
relationship
between
to
provide
better
understanding
underlying
pathogenesis
CVD.
A
total
220,608
initially
CVD-free
participants
were
recruited
from
UK
Biobank
database
categorized
into
non-frailty,
pre-frailty,
groups
based
Fried's
criteria.
The
also
grouped
according
low-grade
(INFLA)
score
its
components:
neutrophil-lymphocyte
ratio,
C-reactive
protein,
white
blood
cell
count,
platelet
count.
Cox
proportional
hazards
models
with
hazard
ratios
(HRs)
95%
confidence
intervals
(CIs)
used
assess
phenotypes
CVD
risk.
Mediation
analysis
was
quantify
association
CVDs.
potential
interactions
terms
evaluated
using
additive
multiplicative
scales.
During
a
median
follow-up
13.3
years,
48,978
developed
After
adjusting
for
various
confounders,
pre-frailty
had
higher
than
those
non-frailty
(HRs:
1.20
(95%
CI:
1.18-1.23)
1.80
1.69-1.91),
respectively).
observed
among
moderate
high
INFLA
scores
low
1.09
1.07-1.12)
1.27
1.24-1.30),
components
limited
mediating
Significant
scale
not
scale.
Inflammation
amplify
harmful
effect
incidence
Improving
alone
might
substantially
reduce
CVDs,
effectively
controlling
help
negative
health.
Abstract
Background
Breast
cancer
survivors
are
at
increased
risk
of
cardiovascular
events
due
to
the
cardiotoxic
effects
treatment.
Exercise
participation
can
lower
various
adverse
health
outcomes.
However,
most
breast
do
not
meet
exercise
guidelines.
Objectives
To
map
and
critically
evaluate
observational
literature
describing
direction
strength
relationship
between
post-diagnosis
leisure-time
(aerobic
muscle-strengthening)
(cardiovascular
disease,
cardiac
function,
related
physiological
factors)
among
diverse
survivors;
identify
variations
in
this
based
on
race,
ethnicity,
and/or
socioeconomic
status.
Methods
Our
scoping
review
was
conducted
accordance
with
established
guidelines
frameworks.
Seven
databases
were
searched.
Participant
characteristics,
findings
regarding
health,
any
extracted.
Article
quality
appraised
using
Mixed
Appraisal
Tool.
Results
Fourteen
sources
identified,
study
varied.
Two
adjusted
analyses
found
aerobic
may
disease.
There
limited
data
an
or
other
outcomes
possible
across
racial,
ethnic,
groups.
Conclusion
Findings
highlight
a
considerable
gap
knowledge
survivors.
Further
longitudinal
research
is
needed
better
establish
relationship,
how
it
differs
PLoS ONE,
Год журнала:
2025,
Номер
20(3), С. e0319658 - e0319658
Опубликована: Март 17, 2025
This
study
examined
the
impact
of
using
bike
desks
on
cognitive
function
and
memory
among
university
students.
Physical
activity
during
adolescence
offers
enduring
health
benefits,
yet
sedentary
behaviors
prevail
young
adults,
posing
significant
risks.
Bike
desks,
integrating
stationary
cycling
with
ergonomic
desk
designs,
aim
to
mitigate
behavior
while
enhancing
performance.
Research
indicates
that
acute
aerobic
exercise
improves
executive
functions,
memory,
attention,
which
is
particularly
beneficial
in
educational
settings.
The
employed
verbal
paired
associates
learning
task
(VPAT)
assess
performance
when
either
usage
at
moderate
intensity
(intervention)
or
rest
(control
condition)
occurred
before
encoding
early
consolidation
26
adult
medicine
nursing
students
a
library
setting.
We
hypothesised
will
enhance
compared
control
condition
rest.
results
our
showed
no
differences
VPAT
scores
response
latency
between
seated
conditions.
Supplementary
analysis,
including
multiple
linear
regression
model
(
R
2
:
0.773,
Adjusted
0.651,
p
<
0.001)
revealed
higher
BMI,
more
frequent
bicycle
usage,
physical
category
were
associated
improved
desk,
vigorous
MET
minutes
per
week
negatively
impacted
analysis
suggests
there
are
potentially
numerous
uncharacterized
modulators
warranting
further
research
identify
understand
these
factors.
