Medicinal Research Reviews, Год журнала: 2025, Номер unknown

Опубликована: Март 23, 2025

ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, inflammation. Conventional cholinergic drugs generally suffer from poor selectivity temporal precision, leading to undesired effects limited therapeutic efficacy. Photopharmacology aims overcome limitations of traditional using photocleavable or photoswitchable ligands spatiotemporal patterns illumination. Spanning muscarinic nicotinic modulators cholinesterase inhibitors, this review explores development application light‐activated compounds tools for unraveling signaling physiological pathological contexts, while also paving way innovative phototherapeutic approaches.

Язык: Английский