Influence of oil phases on the digestibility and curcumin delivery properties of Pickering emulsions DOI Creative Commons
Qing Chen, Xin Di,

Yuge Zhai

и другие.

Food Chemistry X, Год журнала: 2025, Номер 26, С. 102270 - 102270

Опубликована: Фев. 1, 2025

Starch-based Pickering emulsions with four types of oil phases (coconut, corn, olive, and sunflower oils) were fabricated to compare their delivery properties for curcumin. The release rates free fatty acids the bioavailability curcumin investigated using an oral-gastric-intestinal in vitro digestion model. results revealed that prepared corn exhibited highest zero-shear viscosity (η 0 ) infinite-shear ∞ values, indicating its superior physical stability. After 108 h ultraviolet light irradiation at 254 nm, emulsion showed loading rate In simulated small intestinal digestion, FFA different were: coconut (30.74 %) > (15.06 (12.67 olive (12.38 oils. was: (78.01 (64.56 (54.58 (52.51 increased significantly increase starch concentrations.

Язык: Английский

Research Progress on Sesquiterpenoids of Curcumae Rhizoma and Their Pharmacological Effects DOI Creative Commons
Ting Cui, Boyu Li, Fei Liu

и другие.

Biomolecules, Год журнала: 2024, Номер 14(4), С. 387 - 387

Опубликована: Март 23, 2024

Curcumae Rhizoma, a traditional Chinese medicine with wide range of pharmacological activities, is obtained from the dried rhizomes Curcuma phaeocaulis VaL., kwangsiensis S. G. Lee et C. F. Liang, and wenyujin Y. H. Chen Ling. Sesquiterpenoids curcuminoids are found to be main constituents Rhizoma. composed three isoprene units susceptible complex transformations, such as cyclization, rearrangement, oxidation. They most structurally diverse class plant-based natural products biological activities widely in nature. In recent years, scholars have conducted abundant studies on structures properties components This article elucidates chemical structures, medicinal properties, sesquiterpenoids (a total 274 compounds) isolated We summarized extraction isolation methods for sesquiterpenoids, established component library analyzed structural variances among sourced Rhizoma botanical origins. Furthermore, our investigation reveals array sesquiterpenoid types, encompassing guaiane-type, germacrane-type, eudesmane-type, elemane-type, cadinane-type, carane-type, bisabolane-type, humulane-type, other emphasizing relationship between diversity activity. hope provide valuable reference further research exploitation pave way development new drugs derived plants.

Язык: Английский

Процитировано

7

Ferroptosis and circular RNAs: new horizons in cancer therapy. DOI
Asif Ahmad Bhat,

Neelima Kukreti,

Muhammad Afzal

и другие.

PubMed, Год журнала: 2024, Номер 23, С. 570 - 599

Опубликована: Янв. 1, 2024

Cancer poses intricate challenges to treatment due its complexity and diversity. Ferroptosis circular RNAs (circRNAs) are emerging as innovative therapeutic avenues amid the evolving landscape of cancer therapy. Extensive investigations into circRNAs reveal their diverse roles, ranging from molecular regulators pivotal influencers ferroptosis in cell lines. The results underscore significance modulating pathways that impact crucial aspects development, including survival, proliferation, metastasis. A detailed analysis delineates these pathways, shedding light on mechanisms through which influence ferroptosis. Building upon recent experimental findings, study evaluates potential targeting induce By identifying specific associated with etiology cancer, this paves way for development targeted therapeutics exploit vulnerabilities cells. This review consolidates existing understanding circRNAs, emphasizing role therapy providing impetus ongoing research dynamic field. See also graphical abstract(Fig. 1).

Язык: Английский

Процитировано

7

Radix Codonopsis: a review of anticancer pharmacological activities DOI Creative Commons
Caiyue Liu, Zheng Li,

F. Cheng

и другие.

Frontiers in Pharmacology, Год журнала: 2025, Номер 15

Опубликована: Янв. 7, 2025

Radix Codonopsis (Dangshen), derived from the dried root of plants in Campanulaceae family, is a widely used Chinese herbal medicine. It renowned for its pharmacological effects, including tonifying middle qi, invigorating spleen, benefiting lungs, enhancing immunity, and nourishing blood. extract frequently incorporated into health products such as tablets capsules, making it accessible daily maintenance. Additionally, commonly dietary applications like soups, teas, porridges to nourish enrich blood, promote overall vitality. In recent years, increasing attention has been given anti-cancer potential Codonopsis. Studies have identified key active components luteolin, stigmasterol, polyacetylenes, lobetyolin, glycitein, which exhibit anti-tumor properties through mechanisms inhibiting cancer cell growth proliferation, suppressing epithelial-mesenchymal transition (EMT), inducing apoptosis. This review highlights research progress on Codonopsis, constituents, mechanisms, role convergence medicine food modern life. By doing so, aims provide valuable insights references future scientific studies clinical

Язык: Английский

Процитировано

1

STAT3 Orchestrates Immune Dynamics in Hepatocellular Carcinoma: A Pivotal Nexus in Tumor Progression DOI

Ai-Guo Zhang,

H U Songbai,

Chuanzheng Yin

и другие.

Critical Reviews in Oncology/Hematology, Год журнала: 2025, Номер unknown, С. 104620 - 104620

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

1

Influence of oil phases on the digestibility and curcumin delivery properties of Pickering emulsions DOI Creative Commons
Qing Chen, Xin Di,

Yuge Zhai

и другие.

Food Chemistry X, Год журнала: 2025, Номер 26, С. 102270 - 102270

Опубликована: Фев. 1, 2025

Starch-based Pickering emulsions with four types of oil phases (coconut, corn, olive, and sunflower oils) were fabricated to compare their delivery properties for curcumin. The release rates free fatty acids the bioavailability curcumin investigated using an oral-gastric-intestinal in vitro digestion model. results revealed that prepared corn exhibited highest zero-shear viscosity (η 0 ) infinite-shear ∞ values, indicating its superior physical stability. After 108 h ultraviolet light irradiation at 254 nm, emulsion showed loading rate In simulated small intestinal digestion, FFA different were: coconut (30.74 %) > (15.06 (12.67 olive (12.38 oils. was: (78.01 (64.56 (54.58 (52.51 increased significantly increase starch concentrations.

Язык: Английский

Процитировано

1