Results in Chemistry, Год журнала: 2025, Номер unknown, С. 102272 - 102272
Опубликована: Апрель 1, 2025
Язык: Английский
Applied Food Research, Год журнала: 2025, Номер unknown, С. 100849 - 100849
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Nano TransMed, Год журнала: 2025, Номер unknown, С. 100080 - 100080
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Nanomaterials, Год журнала: 2025, Номер 15(4), С. 288 - 288
Опубликована: Фев. 13, 2025
Various metal-based nanomaterials have been the focus of research regarding their use in controlling pests and diseases improving crop yield quality. In this study, we synthesized via a solvothermal procedure pegylated zinc-doped ferrite (ZnFer) NPs characterized physicochemical properties by X-ray diffraction (XRD), vibrating sample magnetometry (VSM), thermogravimetric analysis (TGA), FT-IR UV-Vis spectroscopies, as well transmission electron microscopy (TEM). Subsequently, impact on tomato photosynthetic efficiency was evaluated using chlorophyll fluorescence imaging to estimate light energy photosystem II (PSII), 30, 60, 180 min after foliar spray plants with distilled water (control plants) or 15 mg L-1 30 ZnFer NPs. The PSII responses leaves showed time- dose-dependent biphasic hormetic responses, short-time inhibitory effect low dose stimulatory high dose, while at longer exposure period, reverse phenomenon recorded doses. An function observed more than ~120 both concentrations, implying negative photochemistry. We may conclude that NPs, despite ability induce hormesis photochemistry, function.
Язык: Английский
Процитировано
0
Discover Nano, Год журнала: 2025, Номер 20(1)
Опубликована: Фев. 13, 2025
Abstract Biosynthesis techniques for nanomaterials have advanced significantly, promoting eco-friendly synthesis chemistry as a sustainable alternative to conventional methods. This study presents novel and environmentally friendly approach synthesizing nanoparticulate ZnO, CuO, ZnO/CuO nanocomposites using aqueous extracts of Pleurotus ostreatus spent substrate, is reported. The structural, optical, morphological properties the synthesized NPs were analysed. A hexagonal phase ZnO monoclinic CuO obtained according X-ray diffraction analysis. reduction in peak intensity these metal oxides was observed due reduced crystallinity. absorption spectra, from UV–vis analysis, showed peaks at 354, 365, 525 nm NPs, respectively. An anticancer assay conducted human embryonic kidney (HEK 293) cervical carcinoma (HeLa) cell lines, while 1,1-diphenyl-2-picrylhydrazyl (DPPH) used antioxidant evaluation. higher potency with IC 50 2.15, 2.16, 3.18 µg/mL, respectively, than ascorbic acid (4.25 µg/mL). indicates that nanoparticles more effective capturing DPPH free radicals. Anticancer assays strong cytotoxic effects all nanoparticles, exhibiting highest activity (IC : 1.94 μM HEK 293 cells, 3.23 HeLa cells), surpassing NPs. Cell viability both cells decreased nanoparticle concentration increased, confirming dose-dependent cytotoxicity. green their composite potential biomedical applications.
Язык: Английский
Процитировано
0
Scientific Reports, Год журнала: 2025, Номер 15(1)
Опубликована: Фев. 21, 2025
Abstract Calcium titanate nanoparticles (CaTiO 3 NPs) have garnered significant attention due to their unique properties and excellent biocompatibility, which led increased use in various fields consumer products. This rise application necessitates a better understanding of biological toxicological effects. However, there is limited data on the cytotoxicity genotoxicity CaTiO NPs human normal skin fibroblasts (HSF) non-small lung cancer (A-549) cells. Consequently, this study aimed explore effect 48-hour exposure cell viability, genomic DNA integrity, oxidative stress induction A-549 cells, compared HSF The were assessed using Sulforhodamine B (SRB) Alkaline Comet assays, respectively. To estimate possible variation apoptotic gene expression, reactive oxygen species (ROS) analysis quantitative real-time polymerase chain reaction (qRT-PCR) also performed. Our findings demonstrated that for 48 h resulted low toxicity toward both with death observed only at high concentrations (100 1000 µg/ml). IC50 value cells was greater than µg/ml; specifically, 1670.65 µg /ml. treatment concentration /ml damage excessive ROS generation, along notable disturbance expression level (p53 Bax) anti-apoptotic Bcl2 genes In contrast, no changes treated same (1670.65 /ml) NPs. Collectively, these indicated despite short-term causing selectively genotoxic mediated through disrupted integrity altered genes, triggering apoptosis Further vitro vivo studies are needed fully understand
Язык: Английский
Процитировано
0
Industrial Crops and Products, Год журнала: 2025, Номер 227, С. 120796 - 120796
Опубликована: Март 6, 2025
Язык: Английский
Процитировано
0
Hybrid Advances, Год журнала: 2025, Номер unknown, С. 100430 - 100430
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Medicina, Год журнала: 2025, Номер 61(3), С. 515 - 515
Опубликована: Март 17, 2025
Background and Objectives: This study introduces an innovative approach to accelerating wound healing by leveraging the bactericidal properties of mycosynthesized copper oxide nanoparticles (CuO-NPs) their combination with curcumin against Pseudomonas aeruginosa. The aims evaluate antimicrobial efficacy, impact on quorum sensing-associated virulence factors, potential therapeutic applications in healing. Materials Methods: minimum inhibitory concentration (MIC) (MBC) CuO-NPs were determined be 25 μg/mL 50 μg/mL, respectively. At sub-inhibitory concentrations (0.5 MIC, 0.25 0.125 MIC), effects P. aeruginosa growth factors assessed. Antioxidant activity cytotoxicity also evaluated. Additionally, (CUR) was tested for its enhanced wound-healing efficacy. Results: While did not inhibit at concentrations, they significantly reduced a dose-dependent manner: LasB elastase (81.8%, 60.6%, 53.03%), LasA protease (70%, 68.5%, 57.1%), pyocyanin (85.7%, 71.4%, 55.9%). exhibited strong antioxidant scavenging free radicals. CUR demonstrated highest outperforming negative control Mebo ointment 193.9% 61.6%, selective HepG2 cancer cells while displaying minimal toxicity toward normal human skin cells. Conclusions: CuO-NPs, particularly CUR, show promising as agent inhibiting exhibiting activity, demonstrating cytotoxicity. These findings highlight biomedical applications.
Язык: Английский
Процитировано
0
Results in Chemistry, Год журнала: 2025, Номер unknown, С. 102272 - 102272
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0