Preliminary study on the effects of dry powder and water extract of Neolamarckia cadamba on growth performance, immunity, and intestinal health of yellow-feathered broilers
BMC Veterinary Research,
Год журнала:
2025,
Номер
21(1)
Опубликована: Апрель 2, 2025
In
recent
years,
the
livestock
industry
has
shown
increasing
concern
regarding
need
to
find
effective
alternatives
antibiotic
products
while
also
striving
produce
high-quality
and
poultry
products.
Woody
feed
sources
exhibit
wide
distribution
variety,
containing
a
variety
of
bioactive
substances
such
as
flavonoids
alkaloids.
Among
these
woody
plants,
Neolamarckia
cadamba
(Nc)
characteristics
high
leaf
yield,
fast
growth
rate,
rich
nutritional
value,
which
great
development
potential.
However,
whether
Nc
supplementation
can
improve
performance,
immunity,
gut
health
yellow-feathered
broilers
remains
be
explored.
present
study,
we
aimed
investigate
effects
diet
supplemented
with
dry
powder
or
water
extract
on
intestinal
broilers.
The
results
showed
that,
(1)
There
was
no
significant
difference
in
Body
weight
(BW),
Average
daily
gain
(ADG),
intake
(ADFI),
Feed
conversion
ratio
(FCR)
between
experimental
groups
control
group
(P
>
0.05);
(2)
Compared
group,
thymus
index
at
63
days
significantly
increased
1%
<
0.05).
Conversely,
bursa
Fabricius
decreased
0.05)
same
group;
(3)
there
were
differences
serum
levels
albumin
(ALB),
globulin
(GLB),
total
protein
(TP),
alanine
aminotransferase
(ALT),
aspartate
(AST),
triglycerides
(TG)
each
(4)
IgG
both
0.05%
(5)
could
increase
mRNA
expression
ZO-1
TGF-β4
jejunum,
well
claudin-1,
ZO-1,
ileum(P
Furthermore,
use
resulted
jejunum
ileum
These
suggest
that
dietary
enhance
immune
function,
small
barrier
integrity,
reduce
inflammation
certain
extent.
four
doses
(1%
powder,
2%
0.1%
extract),
more
effective.
findings
underscore
importance
exploring
alternative
additives
production,
they
may
offer
viable
strategy
for
promoting
animal
performance
absence
traditional
antibiotics.
Язык: Английский
Brassinosteroid Signaling Dynamics: Ubiquitination-Dependent Regulation of Core Signaling Components
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(10), С. 4502 - 4502
Опубликована: Май 8, 2025
Brassinosteroids
(BRs)
are
essential
phytohormones
that
orchestrate
various
stages
of
plant
growth
and
development.
The
BR
signaling
cascade
is
mediated
through
a
phosphorylation
network
involving
sequential
activation
the
plasma
membrane-localized
receptor
kinase
Brassinosteroid-Insensitive
1
(BRI1),
cytoplasmic
2
(BIN2),
transcription
factors
BRI1-EMS
suppressor
(BES1)
Brassinazole-Resistant
(BZR1).
These
activate
thousands
nuclear
genes.
Recent
evidence
highlights
ubiquitination
has
emerged
as
an
equally
pivotal
mechanism
dynamically
controls
pathway
by
modulating
activity,
subcellular
localization,
protein
stability
these
core
components.
In
this
review,
we
systematically
analyze
central
role
in
determining
function,
degradation
proteins
to
fine-tune
outputs
signaling.
We
provide
comparative
perspectives
on
functional
conservation
divergence
ubiquitin-related
regulatory
components
model
Arabidopsis
versus
other
species.
Furthermore,
critically
evaluate
current
knowledge
gaps
ubiquitin-mediated
spatiotemporal
control
signaling,
offering
insights
into
potential
research
directions
elucidate
sophisticated
network.
Язык: Английский