Transcranial Vibration Stimulation at 40 Hz Induced Neural Activity and Promoted the Coupling of Global Brain Activity and Cerebrospinal Fluid Flow
NeuroImage,
Год журнала:
2025,
Номер
308, С. 121074 - 121074
Опубликована: Фев. 6, 2025
Neuroscience
advances
have
highlighted
the
potential
of
non-invasive
brain
stimulation
in
influencing
cognitive
and
emotional
processes.
Conventional
methods
such
as
electrical,
magnetic,
ultrasound
been
studied
intensively,
but
little
is
known
about
mechanical
stimulation.
To
investigate
effects
40
Hz
transcranial
vibration
(TVS)
on
human
activity,
specifically
focusing
changes
Amplitude
Low-Frequency
Fluctuation
(ALFF),
fractional
ALFF
(fALFF)
Regional
Homogeneity
(ReHo)
measures
spontaneous
activity.
Additionally,
this
study
investigates
alterations
global
blood-oxygen-level-dependent
(gBOLD)
signal
cerebrospinal
fluid
(CSF)
inflow
coupling,
which
serve
indicators
glymphatic
system
function.
A
custom-built
head
actuator
was
used
to
apply
TVS
brain.
Functional
magnetic
resonance
imaging
(fMRI)
were
performed
before
after
5
minutes
explore
fALFF
coupling
activity
with
flow
(CSF),
related
clearance.
Significant
increases
observed
both
metrics,
indicating
that
effectively
enhanced
promoted
synchronization
overall
CSF,
suggesting
an
improvement
clearance
processes,
effect
30
or
50
did
not
replicate.
Non-invasive
using
provided
important
implications
for
modulating
physiology
showed
prospective
therapeutic
benefits
neurological
diseases.
Язык: Английский
Explainable and Responsible AI in Neuroscience
Опубликована: Март 3, 2025
Exploring Cortical Interneurons in Substance Use Disorder: From Mechanisms to Therapeutic Perspectives
The Neuroscientist,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 8, 2025
Interneurons
(INs)
play
a
crucial
role
in
the
regulation
of
neural
activity
within
medial
prefrontal
cortex
(mPFC),
brain
region
critically
involved
executive
functions
and
behavioral
control.
In
recent
preclinical
studies,
dysregulation
INs
mPFC
has
been
implicated
pathophysiology
substance
use
disorder,
characterized
by
vulnerability
to
chronic
drug
use.
Here,
we
explore
diversity
their
connectivity
roles
addiction.
We
also
discuss
how
these
change
over
time
with
exposure.
Finally,
focus
on
noninvasive
stimulation
as
therapeutic
approach
for
targeting
highlighting
its
potential
restore
circuits.
Язык: Английский
Educating Healthcare Professionals on AI in Alzheimer's Disease
Advances in medical technologies and clinical practice book series,
Год журнала:
2024,
Номер
unknown, С. 372 - 388
Опубликована: Июнь 28, 2024
Alzheimer's
disease
(AD)
is
the
main
cause
of
dementia
in
older
persons.
Preclinical
AD
can
persist
anywhere
from
six
to
ten
years,
depending
on
when
it
first
appears.
Artificial
intelligence
(AI)
create
machines
that
are
capable
doing
tasks
would
typically
require
human
intelligence.
Machine
learning
(ML),
deep
(DL),
and
natural
language
processing
(NLP)
just
a
few
approaches
used
AI.
tools
increasingly
being
predict
beginning
or
course
diseases,
addition
aiding
diagnosis.
AI
has
shown
be
useful
tool
for
improving
customized
care
by
providing
best
possible
treatment
plans.
diagnose
provide
programs,
assist
medical
practitioners
making
decisions.
But
order
apply
healthcare
ethically
successfully,
problems
with
bias,
security
data,
need
understanding
must
addressed.
Язык: Английский
Advancements in non-invasive microwave brain stimulation
Physics of Life Reviews,
Год журнала:
2024,
Номер
48, С. 203 - 204
Опубликована: Фев. 5, 2024
Язык: Английский
Promising neurological treatment via microwave brain stimulation: A comment on “Advancements in non-invasive microwave brain stimulation: A comprehensive survey” by F.E.S. Pereira et al.
Physics of Life Reviews,
Год журнала:
2024,
Номер
49, С. 130 - 131
Опубликована: Апрель 3, 2024
Язык: Английский
Challenges and Future Directions in AI-Driven Alzheimer's Disease Research and Care
Advances in medical technologies and clinical practice book series,
Год журнала:
2024,
Номер
unknown, С. 356 - 371
Опубликована: Июнь 28, 2024
Alzheimer's
sickness
(AD)
is
a
neurodegenerative
that
impacts
thousands
and
of
individuals
globally
major
reason
cognitive
impairment
dementia.
With
the
speedy
boom
synthetic
intelligence
(AI)
technology,
there
have
been
good
sized
advancements
in
research
care
current
years.
These
paper
goals
to
check
modern
demanding
situations
destiny
directions
AI-pushed
ad
care.
It
discusses
kingdom
AI
packages
ad,
which
include
early
analysis,
tracking
disorder
progression,
predicting
treatment
response.
Moreover,
it
highlights
confronted
implementing
AI-driven
care,
includes
moral
worries
information
privacy.
The
also
explores
capacity
effect
optimizing
customized
remedy
plans
improving
affected
person
outcomes.
Lastly,
addresses
future
instructions
advert
studies,
mixing
multiple
facts
resources
development
extra
state-of-the-art
algorithms.
Язык: Английский
AI-Enhanced Drug Discovery for Alzheimer's
Advances in medical technologies and clinical practice book series,
Год журнала:
2024,
Номер
unknown, С. 101 - 113
Опубликована: Июнь 28, 2024
AI-greater
drug
discovery
has
emerged
as
a
promising
approach
inside
the
search
for
effective
remedies
Alzheimer's
ailment.
In
latest
years,
use
of
synthetic
intelligence
(AI)
multiplied
manner
by
means
enhancing
our
understanding
sickness
mechanisms
and
identifying
ability
applicants.
With
aid
leveraging
huge
facts
powerful
computing
algorithms,
AI
strategies
can
analyze
sizable
quantities
biomedical
statistics,
are
expecting
drug-target
interactions,
even
design
new
molecules
with
favored
homes.
This
summary
explores
modern
state
AI-stronger
disorder,
including
capability
benefits
challenges
this
method,
discusses
future
implications
improvement
devastating
situation.
Язык: Английский
Patient-Centered AI Solutions for Managing Alzheimer's Disease
Sheerin Banu M.,
D. Sugumar,
S. Sujatha
и другие.
Advances in medical technologies and clinical practice book series,
Год журнала:
2024,
Номер
unknown, С. 250 - 263
Опубликована: Июнь 28, 2024
Patient-centered
AI
solutions
for
dealing
with
Alzheimer's
ailment
is
a
research-based
totally
article
that
explores
the
ability
of
synthetic
intelligence
(AI)
in
aiding
management
and
remedy
disease
(AD).
disorder
revolutionary
neurodegenerative
sickness
impacts
thousands
people
worldwide.
And
not
using
recognized
treatment,
managing
advert
calls
comprehensive
personalized
technique.
This
text
highlights
key
demanding
situations
cutting-edge
control
introduces
function
addressing
those
situations.
It
additionally
discusses
potential
benefits
patient-targeted
answers
improving
early
detection,
analysis,
advert.
Through
an
assessment
existing
studies,
this
provides
promising
applications
which
include
advanced
imaging,
biomarker
evaluation,
predictive
modeling
identifying
individuals
prone
to
ad
monitoring
development.
Язык: Английский