European Journal of Organic Chemistry,
Год журнала:
2022,
Номер
2022(35)
Опубликована: Авг. 23, 2022
Abstract
A
regioselective
hydroboration/hydrolysis
of
epoxides
with
pinacolborane
catalyzed
by
NaOH/BEt
3
was
achieved.
Glycidyl
oxide,
styrene
oxide
and
adamantane
epoxide
underwent
facile
hydroboration/deprotection
to
provide
secondary
alcohols
exclusive
selectivity
in
good
excellent
yields.
Moreover,
the
stereochemistry
could
also
be
well
retained,
corresponding
were
obtained
high
optical
activity
under
alkaline
catalysis.
Significantly,
this
reaction,
diverse
functional
groups
can
compatible,
including
hydrogenation‐sensitive
groups,
such
as
carbon‐carbon
double
bonds
halogens.
Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
365(6), С. 768 - 819
Опубликована: Янв. 17, 2023
This
review
updates
the
field
of
enantioselective
domino
reactions
promoted
by
chiral
catalysts
derived
from
first
row
metals,
such
as
zinc,
iron,
copper,
scandium,
nickel,
cobalt,
titanium,
chromium
and
magnesium
special
case,
published
since
beginning
2019.
It
illustrates
how
much
a
diversity
these
allow
an
impressive
range
novel
highly
many
types
to
be
achieved,
providing
one-pot
access
very
complex
functionalized
molecules
simple
starting
materials.
Advanced Sustainable Systems,
Год журнала:
2024,
Номер
unknown
Опубликована: Май 15, 2024
Abstract
The
use
of
alkaline
earth‐abundant
metal
catalysts
as
alternatives
to
transition
in
the
depolymerization
plastic
waste
is
a
very
important
research
area.
In
this
work,
first
method
described
for
conversion
polyesters
into
value‐added
compounds
catalyzed
by
magnesium
catalyst.
It
demonstrated
that
commercially
available,
inexpensive
and
air‐stable,
earth
catalyst
Mg(OTf)
2
efficiently
promotes
reductive
several
using
pinacolborane
(HBpin)
reducing
agent
with
good
excellent
yields.
This
also
remains
active
at
least
12
consecutive
polycaprolactone
(PCL)
reactions
yields
between
89%
81%.
efficient
polycarbonate
poly(bisphenol
A
carbonate)
(PC.BPA).
Furthermore,
it
found
successfully
catalyzes
methanolysis
polycarbonates
moderate
temperature
ACS Catalysis,
Год журнала:
2024,
Номер
14(13), С. 9708 - 9733
Опубликована: Июнь 13, 2024
Recent
global
events
have
led
to
the
cost
of
platinum
group
metals
(PGMs)
reaching
unprecedented
heights.
Many
chemical
companies
are
therefore
starting
seriously
consider
and
evaluate
if
where
they
can
substitute
PGMs
for
non-PGMs
in
their
catalytic
processes.
This
review
covers
recent
highly
relevant
applications
non-PGM
catalysts
modern
pharmaceutical
industry.
By
highlighting
these
selected
successful
examples
non-PGM-catalyzed
processes
from
literature,
we
hope
emphasize
enormous
potential
catalysis
inspire
further
development
within
this
field
enable
technology
progress
toward
manufacturing
We
also
present
some
historical
contexts
perceived
advantages
challenges
implementing
environment.
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(6), С. 1412 - 1421
Опубликована: Янв. 23, 2024
Abstract
We
demonstrate
the
application
of
chiral
magnesium
complexes
in
an
asymmetric
carbon‐sulfur
bond‐forming
reaction.
Enantioselective
and
cost‐effective
methodology
under
mild
condition
for
thia‐Michael
addition,
utilizing
situ
generated
dinuclear
magnesium‐ProPhenol
complex,
has
been
developed.
The
versatility
this
protocol
is
demonstrated
with
a
broad
range
thiol
nucleophiles
wide
selection
enones.
Enantioenriched
β‐ketosulfides
are
obtained
good
to
excellent
yields
moderate
enantioselectivity.
presented
catalytic
system
exhibits
tolerance
structurally
different
substrates
while
maintaining
high
This
observation
aligns
proposed
mechanism,
wherein
sulfur
atom
coordinates
catalyst
close
proximity
reaction
center.
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(24), С. 4778 - 4800
Опубликована: Янв. 1, 2024
A
review
is
presented
of
magnesium
catalysis
for
the
synthesis
important
chiral
scaffolds.
Several
motifs
that
are
present
in
classic
ligands
or
natural
products
synthesized
by
Mg(
ii
)
catalytic
methods
briefly
discussed.
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
63(37)
Опубликована: Июнь 15, 2024
Organic-chemical
literature
encompasses
large
numbers
of
catalysts
and
reactions
they
can
effect.
Many
these
examples
are
published
merely
to
document
the
catalysts'
scope
but
do
not
necessarily
guarantee
that
a
given
catalyst
is
"optimal"-in
terms
yield
or
enantiomeric
excess-for
particular
reaction.
This
paper
describes
Machine
Learning
model
aims
improve
such
catalyst-reaction
assignments
based
on
carefully
curated
data.
As
we
show
here
for
case
asymmetric
magnesium
catalysis,
this
achieves
relatively
high
accuracy
offers
out
of-the-box
predictions
successfully
validated
by
experiment,
e.g.,
in
synthetically
demanding
reductions
Michael
additions.
Recent
global
events
have
led
to
the
cost
of
platinum
group
metals
(PGMs)
reaching
unprecedented
heights.
Many
chemical
companies
are
therefore
starting
seriously
consider
and
evaluate
if,
where,
they
can
substitute
PGMs
for
non-PGMs
in
their
catalytic
processes.
This
review
covers
recent
large-scale
applications
non-PGM
catalysts
modern
pharmaceutical
industry.
By
highlighting
these
selected
successful
examples
non-PGM-catalyzed
processes
from
literature,
we
hope
emphasize
enormous
potential
catalysis
inspire
further
development
within
this
field
enable
technology
progress
towards
manufacturing
We
also
present
some
historical
context
perceived
advantages
challenges
implementing
environment.
Angewandte Chemie,
Год журнала:
2024,
Номер
136(37)
Опубликована: Июнь 15, 2024
Abstract
Organic‐chemical
literature
encompasses
large
numbers
of
catalysts
and
reactions
they
can
effect.
Many
these
examples
are
published
merely
to
document
the
catalysts’
scope
but
do
not
necessarily
guarantee
that
a
given
catalyst
is
“optimal”—in
terms
yield
or
enantiomeric
excess—for
particular
reaction.
This
paper
describes
Machine
Learning
model
aims
improve
such
catalyst‐reaction
assignments
based
on
carefully
curated
data.
As
we
show
here
for
case
asymmetric
magnesium
catalysis,
this
achieves
relatively
high
accuracy
offers
out
of‐the‐box
predictions
successfully
validated
by
experiment,
e.g.,
in
synthetically
demanding
reductions
Michael
additions.
