Transcriptomic and metabolomic analyses provide evidence on the biocontrol mechanism responsible for the inhibition of Botrytis cinerea and Alternaria alternata by Bacillus velezensis in kiwifruit DOI Creative Commons

Shixian Zeng,

Xiaojiao Li,

Jinsong Leng

и другие.

Food Frontiers, Год журнала: 2024, Номер 5(6), С. 2623 - 2640

Опубликована: Авг. 20, 2024

Abstract Botrytis cinerea and Alternaria alternata are major pre‐ postharvest plant pathogens of kiwifruit responsible for significant economic losses. Although synthetic fungicides the main source controlling these pathogens, their use can lead to pathogen resistance, pollution environment, residues on agricultural produce represent a health risk humans. Bacillus velezensis is an ecofriendly bacterium with biocontrol potential. The objectives present study were determine efficacy B. against A. , both which kiwifruit, investigate mechanisms its activity using transcriptomic metabolomic methodology. Dual cultures either or versus single used conduct analyses provide insight into mechanism by inhibits . A total 2499 3248 differentially expressed genes (DEGs) identified in / velezensis/A. comparisons, respectively. Genes related sporulation, virulence, hydrolase downregulated associated MAPK signaling TCA cycle also downregulated. Our provides new insights underlying inhibition results demonstrate potential as agent two kiwifruit.

Язык: Английский

Plumbagin controls fungal postharvest pathogens by affecting metabolism and inducing autophagy DOI
Xiaokang Zhang, Yong Chen, Tong Chen

и другие.

Postharvest Biology and Technology, Год журнала: 2024, Номер 212, С. 112904 - 112904

Опубликована: Март 21, 2024

Язык: Английский

Процитировано

8

Current insights into the biocontrol and biotechnological approaches for postharvest disease management of Botrytis cinerea DOI
Faiz Ur Rahman, Qiunan Zhu,

Ziling Wu

и другие.

Postharvest Biology and Technology, Год журнала: 2024, Номер 216, С. 113055 - 113055

Опубликована: Июнь 18, 2024

Язык: Английский

Процитировано

7

A receptor‐like kinase SlFERL mediates immune responses of tomato to Botrytis cinerea by recognizing BcPG1 and fine‐tuning MAPK signaling DOI
Dongchao Ji, Wei Liu,

Xiaomin Cui

и другие.

New Phytologist, Год журнала: 2023, Номер 240(3), С. 1189 - 1201

Опубликована: Авг. 18, 2023

FERONIA (FER) is a receptor-like kinase showing versatile functions during plant growth, development, and responses to environmental stimuli. However, its the interaction between fruit necrotrophic fungal pathogens are still unclear. Combining reverse genetic approaches, physiological assays, co-immunoprecipitation, protein phosphorylation identification, site-directed mutagenesis, we reported tomato FER homolog SlFERL (Solanum lycopersicum Like) involved in immune Botrytis cinerea invasion. The results indicated that extracellular domain recognized interacted with secreted virulence BcPG1 from B. cinerea, further revealed triggered downstream signaling by phosphorylating SlMAP3K18 at Thr45, Ser49, Ser76, Ser135. Moreover, verified SlMAP2K2 SlMAP2K4 synergistically contributed response of which SlFERL-SlMAP3K18 module substantially modulated level and/or activity SlMAP2K2/SlMAP2K4. These findings reveal new pattern-triggered pathway, indicating participates invasion via recognizing fine-tuning MAPK signaling.

Язык: Английский

Процитировано

16

2-Phenylethanol biocontrol postharvest tomato gray mold and its effect on tomato quality DOI
Fangfang Wu,

Yankun Lin,

Bin Zheng

и другие.

Scientia Horticulturae, Год журнала: 2024, Номер 337, С. 113550 - 113550

Опубликована: Авг. 15, 2024

Язык: Английский

Процитировано

4

Mitigating Response of SlCSE06 Induced by 2-Ethylfuran to Botrytis cinerea Infection DOI Creative Commons

Huilan Ye,

Hongdou Gao, Jinnian Li

и другие.

Plants, Год журнала: 2025, Номер 14(4), С. 575 - 575

Опубликована: Фев. 13, 2025

Tomato (Solanum lycopersicum L.) is a major economic vegetable crop globally, yet it prone to gray mold disease caused by Botrytis cinerea infection during cultivation. Caffeoyl shikimate esterase (CSE) crucial component of the lignin biosynthesis pathway, which significantly contributes plant stress resistance. Therefore, investigating expression patterns SlCSE after may offer theoretical foundation for breeding resistant tomato varieties. In this study, 11 family members were identified from genome using bioinformatics analyses. Public transcriptome databases and RT-qPCR experiments used analyze gene in tissues, responses infection, temporal characteristics response 2-ethylfuran treatment infection. These resulted identification key SlCSE06. Transgenic lines that overexpressed SlCSE06 constructed examine their resistance levels disease. Many genes upregulated when fruit infected with ripening stage. Furthermore, 24 h 2-ethylfuran, most exhibited increased compared control group, but they lower at other time points. Thus, enhance responsiveness SlCSEs. Based on research, was as involved The SlCSE06-overexpressing (OE6) plants 197.94% increase wild type (WT). content OE6 higher than WT, suggesting overexpression enhanced formation plants. At 5 days post-inoculation cinerea, lesion diameter decreased 31.88% relative whereas 370.90%. level upregulated, showing 17.08-fold WT. findings suggest enhances activation critical stress, thereby promoting deposition mitigate further cinerea.

Язык: Английский

Процитировано

0

Temporal proteome profiling of Botrytis cinerea reveals proteins involved in plant invasion and survival DOI Creative Commons
Shriya Singh,

Manasa Hegde,

Inderjeet Kaur

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 7, 2025

Abstract Botrytis cinerea is a necrotrophic fungal pathogen that poses significant threat to many crops. Understanding the proteome dynamics of phytopathogens during infection can help combat plant diseases. However, most proteomics studies in face interference from abundant host proteins. Here, we optimized solid media better mimics in-planta conditions and used it perform temporal protein . An agar with 20% tomato fruit extract 2% deproteinised leaf was utilized for label-free quantitative at 12, 36, 72 120 hpi. Out 3244 quantified proteins, 2045 showed differential regulation. Glycosyl hydrolases, pectin esterases, stress DDR48, RhoGEF essential transcription factors were found be upregulated early phase, highlighting their role virulence. Meanwhile, pathways such as macromolecule synthesis, purine, carbohydrate metabolism late-growth phase. Overall, study provides comprehensive understanding infection.

Язык: Английский

Процитировано

0

Characterization of two SGNH family cell death-inducing proteins from the horticulturally important fungal pathogen Botrytis cinerea based on the optimized prokaryotic expression system DOI Creative Commons
Xiaokang Zhang, Zhanquan Zhang, Tong Chen

и другие.

Molecular Horticulture, Год журнала: 2024, Номер 4(1)

Опубликована: Март 7, 2024

Abstract Botrytis cinerea is one of the most destructive phytopathogenic fungi, causing significant losses to horticultural crops. As a necrotrophic fungus, B. obtains nutrients by killing host cells. Secreted cell death-inducing proteins (CDIPs) play crucial role in infection; however, only limited number have been reported. For high-throughput CDIP screening, we optimized prokaryotic expression system and compared its efficiency with other commonly used protein systems. The showed superior effectiveness was selected for subsequent screening. screening verified fifty-five candidate identified two novel SGNH family CDIPs: BcRAE BcFAT. BcFAT exhibited high levels throughout infection process. Site-directed mutagenesis targeting conserved Ser residues abolished activity both Moreover, transient plants enhanced plant resistance against without inducing death, independent their enzymatic activities. Our results suggest high-efficiency provide new targets further study -plant interactions.

Язык: Английский

Процитировано

2

2-Heptanol inhibits Botrytis cinerea by accelerating amino acid metabolism and retarding membrane transport DOI Creative Commons
Fangfang Wu, Haibo Wang,

Yankun Lin

и другие.

Frontiers in Plant Science, Год журнала: 2024, Номер 15

Опубликована: Июнь 3, 2024

During the postharvest storage of tomatoes, they are susceptible to infection by Botrytis cinerea , leading significant economic losses. This study evaluated antifungal potential 2-heptanol (2-HE), a volatile biogenic compound, against B. and explored underlying mechanism. The results indicated that 2-HE effectively suppressed growth mycelia both in vivo vitro stimulated activities antioxidative enzymes, including superoxide dismutase (SOD), peroxidase (POD), catalase (CAT) tomatoes. Furthermore, reduced spore viability, compromised membrane integrity, resulted increased levels extracellular nucleic acids, protein content, lipid peroxidation. Transcriptomic analysis revealed disrupted transport system enhanced amino acid metabolism, which led intracellular nutrient depletion subsequent cell death. Additionally, treatment did not negatively impact appearance or quality In conclusion, findings this offer insights into use as biocontrol agent food agricultural applications.

Язык: Английский

Процитировано

1

Transcriptomic and metabolomic analyses provide evidence on the biocontrol mechanism responsible for the inhibition of Botrytis cinerea and Alternaria alternata by Bacillus velezensis in kiwifruit DOI Creative Commons

Shixian Zeng,

Xiaojiao Li,

Jinsong Leng

и другие.

Food Frontiers, Год журнала: 2024, Номер 5(6), С. 2623 - 2640

Опубликована: Авг. 20, 2024

Abstract Botrytis cinerea and Alternaria alternata are major pre‐ postharvest plant pathogens of kiwifruit responsible for significant economic losses. Although synthetic fungicides the main source controlling these pathogens, their use can lead to pathogen resistance, pollution environment, residues on agricultural produce represent a health risk humans. Bacillus velezensis is an ecofriendly bacterium with biocontrol potential. The objectives present study were determine efficacy B. against A. , both which kiwifruit, investigate mechanisms its activity using transcriptomic metabolomic methodology. Dual cultures either or versus single used conduct analyses provide insight into mechanism by inhibits . A total 2499 3248 differentially expressed genes (DEGs) identified in / velezensis/A. comparisons, respectively. Genes related sporulation, virulence, hydrolase downregulated associated MAPK signaling TCA cycle also downregulated. Our provides new insights underlying inhibition results demonstrate potential as agent two kiwifruit.

Язык: Английский

Процитировано

0