Molecular Mechanism of VSV-Vectored ASFV Vaccine Activating Immune Response in DCs
Veterinary Sciences,
Год журнала:
2025,
Номер
12(1), С. 36 - 36
Опубликована: Янв. 9, 2025
The
vesicular
stomatitis
virus
(VSV)-vectored
African
swine
fever
(ASFV)
vaccine
can
induce
efficient
immune
response,
but
the
potential
mechanism
remains
unsolved.
In
order
to
investigate
efficacy
of
recombinant
viruses
(VSV-p35,
VSV-p72)-mediated
dendritic
cells
(DCs)
maturation
and
inducing
T-cell
functional
effects
on
DC
activation
target
antigens
presentation
were
explored
in
this
study.
results
showed
that
surface-marked
molecules
(CD80,
CD86,
CD40,
MHC-II)
secreted
cytokines
(IL-4,
TNF-α,
IFN-γ)
highly
expressed
virus-infected
DCs.
addition,
co-culture
virus-treated
DCs
with
naive
T
Th1-
Th17-type
responses
effectively
activated.
Taken
together,
study
indicated
VSV-vectored
ASFV
activated
which
provided
a
theoretical
basis
for
development
novel
ASF
vaccines.
Язык: Английский
Toxic Baits as a Strategy for Controlling Invasive Wild Pigs: Acceptability Among Crop Producers
Agriculture,
Год журнала:
2025,
Номер
15(6), С. 572 - 572
Опубликована: Март 7, 2025
Wild
pigs
(Sus
scrofa)
have
become
a
pervasive
issue
in
the
United
States,
causing
significant
damage
to
agricultural
lands
and
ecosystems.
Toxic
baits
been
developed
as
potential
management
tool.
This
study
evaluates
acceptability
of
toxic
bait
usage
among
U.S.
crop
producers
explores
influential
factors
respondent
attitudes.
Using
data
from
survey
11
states,
we
found
that
59.6%
respondents
somewhat
or
completely
agreed
use
their
state
was
acceptable,
71.4%
they
would
be
comfortable
using
if
were
experiencing
problem
with
wild
pigs.
Regression
model
results
revealed
larger
operations
vulnerable
crops
more
likely
find
acceptable.
Producers
who
generated
income
pig
hunting
on
land
tended
less
accepting,
while
those
other
species
accepting.
These
findings
suggest
is
shaped
by
various
economic,
operational,
demographic
but
there
demand
high-value
facing
problem.
Язык: Английский
Comparing shotshell characteristics to optimize aerial removal of wild pigs (Sus scrofa)
Wildlife Research,
Год журнала:
2025,
Номер
52(4)
Опубликована: Март 17, 2025
Context
As
invasive
wild
pigs
(Sus
scrofa)
expand
throughout
North
America,
wildlife
managers
are
increasingly
tasked
with
implementing
strategies
for
alleviating
their
damage
to
anthropogenic
and
natural
resources.
Aims
Aerial
operations,
such
as
shooting
from
helicopters,
now
commonly
used
controlling
pig
populations
in
the
USA.
operators
interested
identifying
more
effective
tools,
choke
tubes
ammunition
that
produce
best
animal
welfare
outcomes
reduce
number
of
shots
required,
while
determining
maximum
shot
distances.
A
strategic
approach
evaluating
shotshell
firearm
options
aerial
operations
can
help
understand
performance
adjust
techniques
accordingly
maximize
lethality
at
various
Methods
We
evaluated
pellet
patterns
ballistics
shotshells
developed
a
strategy
predicting
field
increasing
Key
results
found
distance
target
type
had
strongest
effects
on
lethality,
probability
vital
impact
declining
distances
increased
pellets
per
decreased.
also
penetration
decreased
increased;
however,
heavier
were
less
affected.
Conclusions
Limiting
selection
important
factors
optimizing
operations.
Specifically,
we
recommend
00
buckshot
≥12
situations
where
≤46
m.
None
tested
performed
well
longer
(i.e.
<0.50
lethal
hit
lower
penetration).
Implications
This
research
has
described
perfunctory
comparative
evaluation
optimize
pigs.
Utilizing
enhance
abilities
an
operator
establish
limitations
improve
efficiencies
outcomes.
Язык: Английский
Trap evaluation to optimize wild pig removal efforts in remote settings
Wildlife Research,
Год журнала:
2025,
Номер
52(4)
Опубликована: Апрель 8, 2025
Context
Invasive
wild
pigs
(Sus
scrofa)
are
the
most
abundant,
widespread,
and
economically
significant
large
vertebrate
established
in
Hawaiian
Islands.
Owing
to
their
generalist
diet
rooting
behavior,
alter
soils
watersheds,
negatively
affecting
native
biota.
Aims
Lethal
removal
of
by
trapping
is
often
effective
practical
management
action
reduce
impacts,
but
terrain
access
challenging.
Methods
We
compared
effectiveness
efficiency
three
trap
designs
(i.e.
corral,
box,
passive
net
traps)
on
a
fenced
population
remote
montane
forest
setting
Island
Hawai‘i,
where
use
cellular-activated
‘smart’
traps
was
not
possible.
Key
results
During
high-intensity
efforts
between
30
November
2021
8
May
2022,
we
trapped
euthanized
435
through
162
events.
Although
each
type
effectively
captured
pigs,
more
per
capture
event
than
did
corral
box
traps.
Specifically,
when
using
traps,
approximately
four
event,
which
two
times
with
respectively.
Passive
were
efficient
although
they
performed
similarly
Conclusions
All
types
tested
successfully
typically
traditional
Net
valuable
addition
strategies.
Implications
In
rugged
settings
smart
technology
cannot
be
used,
recommend
incorporating
into
program
optimize
pigs.
Язык: Английский
Regional variation in demographics, reproduction, and body mass growth rates of wild pigs: Implications for population control
Journal of Wildlife Management,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 26, 2024
Abstract
Wild
pigs
are
a
destructive
invasive
species
throughout
many
regions
of
the
world
and
have
proven
difficult
to
control
or
eliminate.
Their
success
as
an
is,
in
part,
from
their
high
reproductive
potential,
which
can
vary
based
on
available
resources,
ancestry,
other
factors.
We
opportunistically
collected
data
demographics
(i.e.,
age
sex),
reproduction,
body
mass
2,762
wild
various
research
operation
activities
Texas,
Alabama,
Hawai'i,
Guam
(USA),
Queensland
(Australia)
during
2016–2024.
evaluated
these
for
differences
among
study
sites
that
might
lead
better
understanding
pig
ecology
more
effective
populations.
found
structures
varied
greatly
sites,
with
areas
intense
having
younger
The
timing
frequency
birth
pulses
also
by
site.
Large
disparities
populations
demonstrated
elasticities
invaded
ranges;
example,
Alabama
site
had
mostly
young
population
fast
growth
rates
2
discernable
per
year,
whereas
older
slow
indistinguishable
pulse.
hypothesized
may
increase
reproduction
females
through
increased
subsequent
maturity.
recommend
managers
identify
seasonal
region,
then
intensively
focus
removing
115
days
gestation
period)
prior
those
pulses.
This
be
counterintuitive
trapping
after
observing
pulse,
but
it
increases
probability
simultaneously
pregnant
any
associated
offspring
previous
litters
remained
female.
evaluating
regional‐specific
intensities
removal
required
reducing
specific
emphasis
whether
compensatory
behaviors
generated
how
avoid
them.
Язык: Английский