miRNAs as cornerstones in chronic lymphocytic leukemia pathogenesis and therapeutic resistance– An emphasis on the interaction of signaling pathways

Pathology - Research and Practice, Год журнала: 2023, Номер 243, С. 154363 - 154363

Опубликована: Фев. 8, 2023

Язык: Английский

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miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay

Pathology - Research and Practice, Год журнала: 2023, Номер 246, С. 154511 - 154511

Опубликована: Май 9, 2023

Язык: Английский

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Decoding hepatocarcinogenesis from a noncoding RNAs perspective

Journal of Cellular Physiology, Год журнала: 2023, Номер 238(9), С. 1982 - 2009

Опубликована: Июль 14, 2023

Abstract Being a leading lethal malignancy worldwide, the pathophysiology of hepatocellular carcinoma (HCC) has gained lot interest. Yet, underlying mechanistic basis liver tumorigenesis is poorly understood. The role some coding genes and their respective translated proteins, then later on, noncoding RNAs (ncRNAs) such as microRNAs have been extensively studied in context HCC pathophysiology; however, implication long (lncRNAs) circular (circRNAs) indeed less investigated. As subclass ncRNAs which elusive for time ago, lncRNAs was found to be involved plentiful cellular functions DNA, RNA, proteins regulation. Hence, it undisputed that dysregulation profoundly contributes via diverse etiologies. Accordingly, represent hot research topic requires prime focus HCC. In this review, authors discuss breakthrough discoveries involving circRNAs contributed contemporary concepts how these could leveraged potential novel diagnostic prognostic biomarkers. Further, review article sheds light on future trends, thereby discussing pathological roles proliferation, migration, epithelial‐to‐mesenchymal transition. Along line reasoning, recommendations targets exploited achieve effective HCC‐related drug development highlighted.

Язык: Английский

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miRNAs as potential game-changers in head and neck cancer: Future clinical and medicinal uses

Pathology - Research and Practice, Год журнала: 2023, Номер 245, С. 154457 - 154457

Опубликована: Апрель 10, 2023

Язык: Английский

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The role of miRNAs in laryngeal cancer pathogenesis and therapeutic resistance – A focus on signaling pathways interplay

Pathology - Research and Practice, Год журнала: 2023, Номер 246, С. 154510 - 154510

Опубликована: Май 8, 2023

Язык: Английский

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The interplay of signaling pathways and miRNAs in the pathogenesis and targeted therapy of esophageal cancer

Pathology - Research and Practice, Год журнала: 2023, Номер 246, С. 154529 - 154529

Опубликована: Май 11, 2023

Язык: Английский

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miRNAs as potential game-changers in retinoblastoma: Future clinical and medicinal uses

Pathology - Research and Practice, Год журнала: 2023, Номер 247, С. 154537 - 154537

Опубликована: Май 19, 2023

Язык: Английский

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Revealing the role of serum exosomal novel long non-coding RNA NAMPT-AS as a promising diagnostic/prognostic biomarker in colorectal cancer patients

Life Sciences, Год журнала: 2024, Номер 352, С. 122850 - 122850

Опубликована: Июнь 18, 2024

Язык: Английский

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Unraveling the ncRNA landscape that governs colorectal cancer: A roadmap to personalized therapeutics

Life Sciences, Год журнала: 2024, Номер 354, С. 122946 - 122946

Опубликована: Авг. 8, 2024

Язык: Английский

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LncRNA NNT-AS1/hsa-miR-485–5p/HSP90 axis in-silico and clinical prospect correlated-to histologic grades-based CRC stratification: A step toward ncRNA Precision

Pathology - Research and Practice, Год журнала: 2023, Номер 247, С. 154570 - 154570

Опубликована: Май 24, 2023

Язык: Английский

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