From diagnosis to therapy: The critical role of lncRNAs in hepatoblastoma DOI

A. Khuzaim Alzahrani,

Abida Khan,

Neelam Singla

и другие.

Pathology - Research and Practice, Год журнала: 2024, Номер 260, С. 155412 - 155412

Опубликована: Июнь 14, 2024

Язык: Английский

Design, Synthesis, and Computational Studies of Novel Pyrazoline-Based Dual EGFR/HER2 Inhibitors with Apoptotic Antiproliferative Activity DOI
Lamya H. Al-Wahaibi, Hani M. Hafez,

Fadwa H. Edrees

и другие.

Journal of Molecular Structure, Год журнала: 2025, Номер unknown, С. 142364 - 142364

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
The Linc009 negatively regulates cell apoptosis in turbot (Scophthalmus maximus L.) during bacterial challenge DOI Creative Commons

Beibei Wang,

Xiaocheng Zhu, Xiaohua Zhuang

и другие.

Comparative Immunology Reports, Год журнала: 2025, Номер unknown, С. 200211 - 200211

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Non-Coding RNAs as Key Regulators of Gasdermin-D Mediated Pyroptosis in Cancer Therapy DOI
Gaurav Gupta, Muhammad Afzal, Ehssan Moglad

и другие.

Pathology - Research and Practice, Год журнала: 2024, Номер 261, С. 155490 - 155490

Опубликована: Июль 26, 2024

Язык: Английский

Процитировано

3
Current concepts of the crosstalk between lncRNA and E2F1: shedding light on the cancer therapy DOI Creative Commons
Peng Huang,

Feng Wen,

Qiu Li

и другие.

Frontiers in Pharmacology, Год журнала: 2024, Номер 15

Опубликована: Июль 25, 2024

Long noncoding RNAs (lncRNAs) constitute a distinctive subset of RNA molecules with limited protein-coding potential, which exert crucial impacts on various biological activities. In the context cancer, dysregulated lncRNAs function as essential regulators that affect tumor initiation and malignant progression. These serve competitive endogenous (ceRNAs) through sponging microRNAs regulating expression targeted genes. Moreover, they also directly bind to RNA-binding proteins, can be integrated into complex mechanistic network. E2F1, an extensively studied transcription factor, mediates multiple behaviors by cell cycle progression, metastasis, therapeutic response. Emerging evidence suggests play pivotal role in E2F1 pathway. This review aims elucidate intricate gene regulatory programs between cancer We elaborate distinct networks involved emphasizing potential lncRNAs/E2F1 axes promising targets for therapy. Additionally, we provide novel perspectives current evidence, limitations, future directions targeting human cancers. Fully deciphering network lncRNA/E2F1-mediated mechanisms could facilitate translation findings clinical course, such efforts ultimately significantly improve prognosis patients.

Язык: Английский

Процитировано

2
Role of long non-coding RNAs in neurofibromatosis and Schwannomatosis: pathogenesis and therapeutic potential DOI
Md Sadique Hussain, Somya Sharma,

Alka Kumari

и другие.

Epigenomics, Год журнала: 2024, Номер 16(23-24), С. 1453 - 1464

Опубликована: Ноя. 27, 2024

Neurofibromatosis (NF) is identified as genetic disorder characterized by multiple tumors on nerve tissues. NF1 the most prevalent form, neurofibromas and skin changes. neurofibromatosis disorder, distinct from rarer NF2 schwannomatosis (SWN) conditions. NF2, including NF2-related SWN (NF2-SWN), predominantly involves schwannoma formation differs

Язык: Английский

Процитировано

1
The role of GATA4 in mesenchymal stem cell senescence: A new frontier in regenerative medicine DOI Creative Commons
M. Arockia Babu,

Renuka Jyothi S,

Irwanjot Kaur

и другие.

Regenerative Therapy, Год журнала: 2024, Номер 28, С. 214 - 226

Опубликована: Дек. 25, 2024

Язык: Английский

Процитировано

0
From diagnosis to therapy: The critical role of lncRNAs in hepatoblastoma DOI

A. Khuzaim Alzahrani,

Abida Khan,

Neelam Singla

и другие.

Pathology - Research and Practice, Год журнала: 2024, Номер 260, С. 155412 - 155412

Опубликована: Июнь 14, 2024

Язык: Английский

Процитировано

0