Salmonellosis: An Overview of Epidemiology, Pathogenesis, and Innovative Approaches to Mitigate the Antimicrobial Resistant Infections

Antibiotics, Год журнала: 2024, Номер 13(1), С. 76 - 76

Опубликована: Янв. 13, 2024

Salmonella is a major foodborne pathogen and leading cause of gastroenteritis in humans animals. highly pathogenic encompasses more than 2600 characterized serovars. The transmission to occurs through the farm-to-fork continuum commonly linked consumption animal-derived food products. Among these sources, poultry products are primary contributors, followed by beef, pork, fish, non-animal-derived such as fruits vegetables. While antibiotics constitute treatment for salmonellosis, emergence antibiotic resistance rise multidrug-resistant (MDR) strains have highlighted urgency developing alternatives. Effective infection management necessitates comprehensive understanding pathogen’s epidemiology dynamics. Therefore, this review focuses on epidemiology, sources infection, risk factors, dynamics, host range serotypes. This also investigates disease characteristics observed both animals, resistance, pathogenesis, potential strategies control emphasizing most recent antibiotic-alternative approaches control.

Язык: Английский

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Effects of Astaxanthin on Growth Performance, Intestinal Integrity, and Microbiota in Salmonella Enteritidis-Infected Chickens

Poultry Science, Год журнала: 2025, Номер unknown, С. 105056 - 105056

Опубликована: Март 1, 2025

This study investigated the effects of astaxanthin (AST) supplementation in drinking water on growth performance, intestinal barrier function, and cecal microbiota broilers challenged with Salmonella Enteritidis. During 20-day experiment, two hundred forty 1-day-old male Arbor Acres birds were randomly assigned into a 2 × factorial design four groups: non-challenged control (CON), an S. Enteritidis-challenged group (SA), receiving AST treatment (AST), (SA+AST). Each comprised six replicate groups, groups inoculated Enteritidis from day to 4. The results indicated that infection significantly reduced average daily feed intake (ADFI) adversely affected gain (ADG) conversion ratio (FCR) by 20. improved FCR. While did not affect ileal mucosa antioxidation, it decreased villus height height-to-crypt depth (VCR), downregulated mRNA expression ZO-1 Occludin. However, enhanced antioxidant capacity (T-AOC), increased VCR ileum, notably upregulated MUC2 levels, particularly mitigating adverse crypt depth. Furthermore, both α- β-diversity microbiota. Infection was associated changes at phylum level, including significant increases Alistipes, unclassified_f__Lachnospiraceae, bacteria Clostridia UCG-014 grouping, alongside notable decreases Bacteroides, Akkermansia, Blautia, Butyricicoccus. abundance norank_f__Ruminococcaceae Lachnoclostridium unclassified_f__Lachnospiraceae group. In conclusion, could improve performance health

Язык: Английский

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Nationwide surveillance and characterization of the third-generation cephalosporin-resistant Salmonella enterica serovar Infantis isolated from chickens in South Korea between 2010 and 2022

Heliyon, Год журнала: 2024, Номер 10(17), С. e37124 - e37124

Опубликована: Авг. 29, 2024

The occurrence of extended-spectrum β-lactamase (ESBL)/AmpC β-lactamase-producing

Язык: Английский

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Ecological prevalence and genomic characterization of Salmonella isolated from selected poultry farms in Jiangxi province, China

Poultry Science, Год журнала: 2025, Номер 104(7), С. 105197 - 105197

Опубликована: Апрель 25, 2025

Язык: Английский

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Occurrence, Antimicrobial Resistance, and Virulence Profiles of Salmonella Serovars Isolated from Wild Reptiles in South Africa

International Journal of Microbiology, Год журнала: 2024, Номер 2024, С. 1 - 9

Опубликована: Янв. 5, 2024

Reptiles are carriers of an array microorganisms, including significant zoonotic bacteria the genus

Язык: Английский

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The influence of dietary supplementation with fermented agro-industrial residue of faba bean on Japanese quail performance, immunity, gut microbiota, blood chemistry, and antioxidant status

Poultry Science, Год журнала: 2024, Номер 103(9), С. 103880 - 103880

Опубликована: Май 17, 2024

Antibiotic overuse in poultry feeds has disastrous implications; consequently, long-term alternatives must be developed. As a result, the current study aims to assess impact of Aspergillus niger filtrate (ANF) high organic acids grown on agro-industrial residue faba bean (AIRFB) quail diet, as well their influence bird productivity, digestion, carcass yield, blood chemistry, and intestinal microbiota. A total 240 Japanese quails (aged 7 d) were used this study, divided equally among 5 experimental groups with 48 each. Group 1 (G1) received basal diet without any ANF, group 2 (G2) supplemented 0.5 mL ANF/kg 3 (G3) 1.0 4 (G4) 1.5 (G5) diet. The performance parameters monitored at 3, 5, wk. Adding ANF increased body weight wk, gain compared control fed had highest feed conversion ratio group. addition no effect carcass, gizzard, heart, liver, giblets, or dressing; however, it did lower triglycerides, low-density lipoprotein, very lipoprotein while increasing high-density levels. that enhanced immunological indices such IgG, IgM, IgA, lysozymes. It also levels superoxide dismutase antioxidant contents, catalase, digestive enzymes protease, amylase, lipase. However, lowered MDA control. been demonstrated gut microbiota, Escherichia coli, coliforms, population Salmonella are all reduced ANF-fed quails. Histological examination quails' liver sections revealed normal hepatic parenchyma, typical leaf-like villi, comparatively short frequently free lumina. In conclusion, showed improvements performance, enzymes, indices, immunity, capacity reduce pathogenic bacteria after consuming ANF.

Язык: Английский

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Serotype Distribution and Antimicrobial Resistance of Salmonella Isolates from Poultry Sources in China

Antibiotics, Год журнала: 2024, Номер 13(10), С. 959 - 959

Опубликована: Окт. 11, 2024

Background: Salmonella is an important zoonotic pathogen, of which poultry products are reservoirs. This study analyzed the prevalence, antimicrobial resistance, and characterization from broiler laying hen sources in China. Methods: A total 138 (12.27%) strains were isolated 1125 samples slaughterhouses (20.66%, 44/213), farms (18.21%, 55/302), (6.39%, 39/610). Multiplex PCR was used to identify serotypes. Antibiotic susceptibility testing a set 21 antibiotics performed all screened by for 24 selected resistance genes (ARGs). In addition, out whole-genome sequencing together with 65 released genomes evaluate phylogenetic characteristics, multilocus sequence typing (MLST), plasmid carriage percentages. Results: 11 different serotypes identified, dominance S. Enteritidis (43/138, 31.16%), Newport (30/138, 21.74%), Indiana (19/138, 13.77%). The results showed that (34.34%, 34/99) (51.28%, 20/39) dominant isolates broilers hens, respectively. highest sulfisoxazole (SXZ, 100%), nalidixic acid (NAL, 54.35%), tetracycline (TET, 47.83%), streptomycin (STR, 39.86%), ampicillin (AMP, 39.13%), chloramphenicol (CHL, 30.43%), while sensitive both tigacycline (TIG) colistin (COL). 45.65% (63/138) multidrug-resistant (MDR) strains, most them (61/63, 96.83%) sources. assays revealed 63.77% carrying quinolone gene qnrD, followed gyrB (58.70%) trimethoprim dfrA12 (52.17%). Moreover, thirty-four ARGs, eighty-nine virulence genes, eight replicons detected twenty-four among carry ARGs fewest compared other Conclusions: high percentage sources, stressing importance continuous monitoring chain, emergency strategies should be implemented address this problem.

Язык: Английский

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Occurrence, virulence, and resistance genes in Salmonella enterica isolated from an integrated poultry company in Jordan

Poultry Science, Год журнала: 2024, Номер 103(6), С. 103733 - 103733

Опубликована: Апрель 4, 2024

Salmonella is considered one of the most common foodborne pathogens worldwide. The annual number hospitalizations and deaths related to zoonotic salmonellosis, which transmitted from animals humans infects poultry meat, expected be significant. Hence, primary aims this research were isolate characterize species obtained an integrated company identify some virulence, antimicrobial resistance, with a specific concern about colistin resistance genes. A total 635 samples collected various sources in Jordan screened for accompanying their virulence Samples parent stock house drag swabs, broiler farms, premix, cecum at slaughterhouse level, pre-chilling post-chilling stages, final product. detected 3% (6\200) investigated 13.8% (11/80) cloacal swabs 16.9% (11/65) boiler farms 24.4% (11/45) 16.4% (9/55) stage, 37.8% (17/45) stage 53.3% (24/45) product stage. No isolates feed mills (0/20), parents' premix (0/40), or hatcheries (0/40). resistant ciprofloxacin (91.0%), nalidixic acid (86.5%), doxycycline (83.1%), tetracycline sulphamethoxazole-trimethoprim (79.8%) ampicillin (76.4%). Serotyping shows that S. Infantis was predominant serovar, 56.2%. Based on minimum inhibitory concentration (MIC) test, 39.3% (35/89) colistin; however, no mcr genes detected. Among antimicrobial-resistant genes, blaTEM prevalent (88.8%). Furthermore, spvC, ompA, ompF showed highest percentages (97.8%, 97.8%, 96.6%, respectively). In conclusion, found stages company. serotype. Cross-contamination between production highlights importance good hygiene practices. presence patterns present significant challenges public health.

Язык: Английский

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Contamination Status and Serotypes Distribution of Salmonella in Food in Yantai City, China: A 14-Year Continuous Monitoring Study

Foodborne Pathogens and Disease, Год журнала: 2024, Номер unknown

Опубликована: Авг. 9, 2024

is a foodborne zoonotic pathogen that threatens food safety and public health. However, few people have conducted long-term systematic studies on

Язык: Английский

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Effect of Lippia origanoides Essential Oil Extract on Salmonella serovar Enteritidis as a Natural Alternative to Antibiotics in the Poultry Industry

Опубликована: Янв. 1, 2024

Язык: Английский

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