New insights into resveratrol attenuates hepatotoxicity in emamectin benzoate-exposed grass carp (Ctenopharyngodon idella) via NO system/NF-κB signaling pathway
Pesticide Biochemistry and Physiology,
Год журнала:
2024,
Номер
202, С. 105941 - 105941
Опубликована: Май 3, 2024
Язык: Английский
Structural characterization and immune modulation activities of Chinese Angelica polysaccharide (CAP) and selenizing CAP (sCAP) on dendritic cells
International Journal of Biological Macromolecules,
Год журнала:
2024,
Номер
277, С. 132628 - 132628
Опубликована: Май 24, 2024
Язык: Английский
Dietary resveratrol supplementation alleviates cold exposure-induced pyroptosis and inflammation in broiler heart by modulating oxidative stress and endoplasmic reticulum stress
Poultry Science,
Год журнала:
2024,
Номер
103(11), С. 104203 - 104203
Опубликована: Авг. 10, 2024
To
explore
the
potential
protective
effect
of
resveratrol
(RES)
on
cold-exposed
broilers,
360
21-day-old
broilers
were
equally
divided
into
5
groups
with
6
replicates.
A
control
(CON)
group
was
reared
at
normal
feeding
temperature
and
received
a
basal
diet,
4
cold
exposure
(8
±
1°C
for
10
h/d
from
d
29
to
42)
fed
diet
0
(CE),
250
(CE
+
RES250),
500
RES500),
750
RES750)
mg/kg
RES
22
42.
Broilers
slaughtered
42
heart
tissues
collected
measure
relevant
indexes.
The
results
showed
that
all
CE-broilers
had
inflammatory
cell
infiltrations,
dietary
supplementation
reduced
this
phenomenon.
Compared
CON
group,
concentrations
MDA
H
Язык: Английский
Enhanced propionate and butyrate metabolism in cecal microbiota contributes to cold-stress adaptation in sheep
Microbiome,
Год журнала:
2025,
Номер
13(1)
Опубликована: Апрель 24, 2025
Язык: Английский
Activation of GABABR Attenuates Intestinal Inflammation by Reducing Oxidative Stress through Modulating the TLR4/MyD88/NLRP3 Pathway and Gut Microbiota Abundance
Antioxidants,
Год журнала:
2024,
Номер
13(9), С. 1141 - 1141
Опубликована: Сен. 21, 2024
Oxidative
stress
emerges
as
a
prominent
factor
in
the
onset
and
progression
of
intestinal
inflammation,
primarily
due
to
its
critical
role
damaging
cells
tissues.
GABAergic
signaling
is
important
occurrence
development
various
disorders,
yet
effect
on
oxidative
remains
unclear.
We
attempted
assess
whether
participated
regulation
during
enteritis.
The
results
showed
that
lipopolysaccharide
(LPS)
significantly
decreased
γ-aminobutyric
acid
(GABA)
levels
ileal
tissues
mice.
Interestingly,
application
GABA
repressed
shedding
mucosal
epithelial
inflammatory
cell
infiltration,
inhibited
expressions
proinflammatory
factors,
including
granulocyte
colony-stimulating
granulocyte-macrophage
colony
stimulating
factor,
enhanced
anti-inflammatory
cytokines
interleukin
(IL)-4
IL-10,
indicating
could
alleviate
enteritis
This
observation
was
further
supported
by
transcriptome
sequencing,
revealing
total
271
differentially
expressed
genes,
which
exhibited
marked
enrichment
immune-related
pathways,
alongside
enhancement
B
receptor
(GABA
Язык: Английский
Silybin protected from avermectin-induced carp (Cyprinus carpio) nephrotoxicity by regulating PPAR-γ-involved inflammation, oxidative stress, ferroptosis and autophagy
Aquatic Toxicology,
Год журнала:
2024,
Номер
273, С. 107011 - 107011
Опубликована: Июнь 21, 2024
Язык: Английский
Effects of In-Ovo Injection of Yu Ping Feng Polysaccharides on Growth Performance, Intestinal Development, and Immunity in Broiler Chickens
Poultry Science,
Год журнала:
2024,
Номер
104(1), С. 104574 - 104574
Опубликована: Ноя. 24, 2024
Язык: Английский
Cadmium Exposure Induces Inflammation Through Oxidative Stress-Mediated Activation of the NF-κB Signaling Pathway and Causes Heat Shock Response in a Piglet Testis
Biological Trace Element Research,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 4, 2024
Язык: Английский
Prolonged exposure to a music-enriched environment mitigates acute noise-induced inflammation and apoptosis in the chicken spleen by modulating the Keap-1/Nrf2 and NF-κB pathways
Haowen Wang,
Yulai Wang,
Yiwen Chai
и другие.
Poultry Science,
Год журнала:
2024,
Номер
103(10), С. 104100 - 104100
Опубликована: Июль 15, 2024
The
rise
of
operational
noise
as
an
environmental
pollutant
for
farm
animals
is
emerging
concern.
mechanisms
through
which
music
can
alleviate
oxidative
stress,
inflammation,
and
apoptosis
induced
by
exposure
remain
underexplored.
This
study
aims
to
investigate
the
alleviating
effects
underlying
long-term
on
noise-induced
damage
chicken
spleen.
Male
Arbor
Acres
(AA)
broilers
were
divided
into
four
groups:
control
(C),
acute
stimulation
(NS),
with
mitigation
(NSM),
only
(M).
NS
NSM
groups
exposed
(simulating
sudden
intensity
noise,
115
120dB)
10
minutes
daily
a
week,
starting
at
14-days-old.
M
then
received
28
days
6-hour
(Mozart
K.448,
60-65
dB).
results
showed
that
significantly
activated
Keap-1/Nrf2
NF-κB
signaling
pathways.
Long-term
intervention
has
also
been
demonstrated
successfully
mitigate
stress
abnormal
stimulation.
Microscopic
examination
spleen
revealed
resulted
in
increase
splenic
cells,
decrease
lymphocytes,
blurred
boundaries
between
red
white
pulps
group.
However,
these
pathological
changes
alleviated
group
following
intervention.
Compared
group,
exhibited
elevated
parameters.
In
contrast,
notably
improved
antioxidant
capacity
partially
morphological
abnormalities
Additionally,
pathway,
upregulating
downstream
genes
inflammatory
factors
IL-1β,
IL-6,
TNF-α.
Noise-induced
mitochondrial
led
apoptosis,
observed
TUNEL
staining,
along
increased
gene
protein
expression
Bcl-2,
Bax,
Cyt-C,
Casp-3,
Casp-8,
Casp-9.
These
findings
indicate
induce
via
modulating
Prolonged
effectively
mitigates
damage,
offering
vital
experimental
foundation
further
research
pollution's
impact
organisms
music's
role.
Язык: Английский
Microalgal Astaxanthin Ameliorates Cypermethrin-Induced Necroptosis and Inflammation via Targeting Mitochondrial Ca2+ Homeostasis and the ROS-NF-κB-RIPK3/MLKL Axis in Carp Hepatocytes (Cyprinus carpio)
S Li,
Yinuo Liu,
Di Li
и другие.
Fish & Shellfish Immunology,
Год журнала:
2024,
Номер
unknown, С. 109944 - 109944
Опубликована: Окт. 1, 2024
Язык: Английский