A systematic review of the Trier Social Stress Test methodology: Issues in promoting study comparison and replicable research

Neurobiology of Stress, Год журнала: 2020, Номер 13, С. 100235 - 100235

Опубликована: Июнь 15, 2020

Since its development in 1993, the Trier Social Stress Test (TSST) has been used widely as a psychosocial stress paradigm to activate sympathetic nervous system and hypothalamic-pituitary-adrenal axis (HPAA) systems, stimulating physiological functions (e.g. heart rate) cortisol secretion. Several methodological variations introduced over years have led scientific community question replication between studies. In this systematic review, we Preferred Reporting Items of Systematic Reviews Meta-Analysis (PRISMA) synthesize procedure-related data available about TSST protocol highlight commonalities differences across We noted significant discrepancies studies how researchers applied protocol. particular, testing procedures (e.g., number judges, initial arithmetic task, time collected saliva samples for cortisol) discuss possible misinterpretation comparing findings from failing control variables or using modified version original Further, recommend that use standardized background questionnaire when identify factors may influence measurements tandem with summary review guide. More implementation detailed reporting methodology will promote study replication, optimize comparison findings, foster an informed understanding affecting responses social stressors healthy people those pathological conditions.

Язык: Английский

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Stress before conception and during pregnancy and maternal cortisol during pregnancy: A scoping review

Psychoneuroendocrinology, Год журнала: 2023, Номер 153, С. 106115 - 106115

Опубликована: Апрель 18, 2023

Stress before conception and during pregnancy is associated with less favorable maternal child health. Alterations in prenatal cortisol levels may serve as a central biological pathway linking stress to adverse Research examining associations between from childhood through has not been comprehensively reviewed.

Язык: Английский

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Newborn infants’ hair cortisol levels reflect chronic maternal stress during pregnancy

PLoS ONE, Год журнала: 2018, Номер 13(7), С. e0200279 - e0200279

Опубликована: Июль 6, 2018

Cortisol obtained from hair samples represents a retrospective biomarker of chronic stress experienced by the subject in previous months. Although cortisol levels have been used to study relationship between maternal and neonatal primates, this has not yet performed humans using longitudinal design focusing specifically on association. Therefore, objective was determine whether existed psychological during pregnancy postpartum, levels. The sample consisted 80 pregnant women their newborn infants. We conducted assessment levels, stress, anxiety, depression three trimesters postpartum. After childbirth, were also measured. found that first trimester negatively predicted Perceived third lower cortisol, whereas pregnancy-specific same had positive relation with cortisol. is essential for embryonic fetal development; consequently, if synthesis affected high such development could be impaired.

Язык: Английский

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Maternal prenatal psychological distress and hair cortisol levels associate with infant fecal microbiota composition at 2.5 months of age

Psychoneuroendocrinology, Год журнала: 2020, Номер 119, С. 104754 - 104754

Опубликована: Июнь 5, 2020

Maternal prenatal stress associates with infant developmental outcomes, but the mechanisms underlying this association are not fully understood. Alterations in composition and function of intestinal microbiota may mediate some observed health effects, a viewpoint that is supported by animal studies along small human study showing exposure to modifies offspring's microbiota. In current study, we aim investigate associations between maternal psychological distress (PPD) hair cortisol concentration (HCC) fecal large prospective cohort. The population was drawn from FinnBrain Birth Cohort Study. PPD measured standardized questionnaires (EPDS, SCL, PRAQ-R2, Daily Hassles) three times during pregnancy (n = 398). A measure addressing chronicity composed separately for each questionnaire. HCC five cm segment at gestational week 24 115), thus covering early mid-pregnancy. Infant samples were collected age 2.5 months analyzed 16S rRNA amplicon sequencing. chronic (all symptom measures) showed positive (FDR < 0.01) bacterial genera phylum Proteobacteria, potential pathogens, infants. Further, (SCL, Hassles negative scale) associated negatively Akkermansia. Lactobacillus. Neither nor diversity. Chronic symptoms elevated associate alterations composition. keeping earlier literature, increases fromProteobacteria phylum. Further research needed understand how these changes linked later child outcomes.

Язык: Английский

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Innovations in biological assessments of chronic stress through hair and nail cortisol: Conceptual, developmental, and methodological issues

Developmental Psychobiology, Год журнала: 2019, Номер 61(3), С. 465 - 476

Опубликована: Фев. 10, 2019

Abstract Much of the existing research on biological mechanisms underlying stress experience has focused largely moment‐to‐moment stress, rather than chronic , an arguably more powerful predictor long‐term outcomes. Recent methodological innovations have paved way for new lines with promising implications developmental researchers and those who study health adversity. In particular, there are increasing studies that assessments by relying cortisol derived from hair nails as a biomarker stress. this paper, we provide overview their use, describe how nail ought to be conceptualized differently across lifespan, factors may impact its interpretation, circumstances under which use methodologically sensible. The purpose review is provoke further discussion encourage careful designs utilize understanding effects exposure early period, adverse contexts, in association psychological physical

Язык: Английский

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The Impact of Parental Role Distributions, Work Participation, and Stress Factors on Family Health-Related Outcomes: Study Protocol of the Prospective Multi-Method Cohort “Dresden Study on Parenting, Work, and Mental Health” (DREAM)

Frontiers in Psychology, Год журнала: 2019, Номер 10

Опубликована: Июнь 12, 2019

The Dresden Study on Parenting, Work, and Mental Health ("DResdner Studie zu Elternschaft, Arbeit und Mentaler Gesundheit", DREAM) aims to prospectively investigate the relationship between parental work participation, role distribution, stress factors, their effects perinatal outcomes long-term family mental somatic health in a community sample targeting N = 4,000 individuals, i.e., 2,000 couples, expecting child residing Dresden, Germany (interim of 1,410 participants, recruitment ongoing). Various questionnaires are completed at four measurement points from pregnancy two years postpartum (prolongation into middle childhood planned). Applying multi-method approach, endocrinological data (analyses hair cortisol concentrations other endogenous hormones, "DREAMHAIR") qualitative interview (regarding gender attitudes distribution domestic work, care, paid employment; "DREAMTALK") obtained. In this study protocol, theoretical background, methods, preliminary results considering sociodemographic characteristics during birth-related factors eight weeks presented. Additionally, there is focus our sub-study DREAMHAIR. currently comprising 152 88 families (recruitment ongoing), we want gain knowledge transgenerational processes regulation psychopathology whole by analyzing both parents children course (or after birth regarding children) least postpartum. By comparing clinical mothers with disorders, children, partners period admission discharge mother-baby unit post-treatment ("DREAMMBU"), mothers' psychopathology, parent-infant interaction, infant disorders special regard correlates will be examined. With previous studies neglecting fathers or involved, major advantage DREAM use multi-level approach examining longitudinal design. Therefore, contribute better understanding social, for its natural becoming family.

Язык: Английский

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Associations between psychological distress and hair cortisol during pregnancy and the early postpartum: A meta-analysis

Psychoneuroendocrinology, Год журнала: 2022, Номер 147, С. 105969 - 105969

Опубликована: Окт. 28, 2022

Язык: Английский

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Trans-generational stress regulation: Mother-infant cortisol and maternal mental health across the perinatal period

Psychoneuroendocrinology, Год журнала: 2019, Номер 109, С. 104374 - 104374

Опубликована: Июль 29, 2019

Язык: Английский

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Maternal prenatal hair cortisol is associated with prenatal depressive symptom trajectories

Psychoneuroendocrinology, Год журнала: 2019, Номер 109, С. 104383 - 104383

Опубликована: Июль 30, 2019

Maternal prenatal cortisol levels have been inconsistently associated with self-reports of psychological distress (PD). Previous research has linked hair concentration (HCC) evaluating cumulatively the previous months cross-sectional PD measures that usually cover past week(s), which may lead to misleading conclusions on their relations. We aimed investigate how maternal HCC relates cumulative across pregnancy.Subjects (N = 595) were drawn from FinnBrain Birth Cohort Study. was measured samples collected at gestational week (gwk) 24 (HCC1, n 467) and delivery (HCC2, 222). As HCC1 HCC2 comprised mostly different subjects, they considered as independent populations. assessments gwks 14, 24, 34 Edinburgh Postnatal Depression Scale (EPDS), anxiety subscale Symptom Checklist (SCL-90), Pregnancy-Related Anxiety Questionnaire -Revised2 (PRAQ-R2), a daily hassles scale. Cumulative mean scores two consecutive (mean1 14 24; mean2 34). In addition, EPDS SCL modelled by using growth mixture modelling identify symptom trajectory categories. Regression models adjusted for age, body mass index, education use selective serotonin/serotonin-norepinephrine reuptake inhibitor medication.In regression model, higher related "consistently elevated" depressive symptoms in comparison low" (β =.71, p =.021) "low increasing" =.82, .011) trajectories. Additionally, (mean 1) relationships 0.25, .004). General or pregnancy-related unrelated after adjustment covariates.The assessment can reveal important associations HCC, even though are generally weak. Of dimensions PD, trajectories most consistently end-pregnancy levels.

Язык: Английский

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Maternal childhood maltreatment and perinatal outcomes: A systematic review

Journal of Affective Disorders, Год журнала: 2022, Номер 302, С. 139 - 159

Опубликована: Янв. 15, 2022

Maternal childhood maltreatment (MCM) is linked to poor perinatal outcomes but the evidence base lacks cohesion. We explore impact of MCM on four outcome domains: pregnancy and obstetric; maternal mental health; infant; quality care-giving environment. Mechanisms identified in included studies are discussed relation programming hypothesis directions for future research. completed a comprehensive literature search eight electronic databases. Independent assessments were conducted PRISMA protocols applied data extraction. Inclusion criteria was met by N = 49 studies. consistently associated with difficulties infant emotional regulation disturbances mother-infant relationship. Directly observed maternal-reported relationship often mediated mothers' current symptoms psychopathology. Direct associations between adverse obstetric suggested limited number Emotional sexual abuse most consistent subtype significantly outcomes. A meta-analysis not possible due inconsistent reporting generally small infants. Evidence suggests these disruptions functioning. Future research should biological psychosocial mechanisms underpinning specific subtypes Services have unique opportunity screen detect women infants at risk during period.

Язык: Английский

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