A Computational Fluid Dynamics Analysis of BiPAP Pressure Settings on Airway Biomechanics Using a CT-Based Respiratory Tract Model
Respiratory Physiology & Neurobiology,
Год журнала:
2025,
Номер
unknown, С. 104397 - 104397
Опубликована: Янв. 1, 2025
Язык: Английский
Large eddy simulation-based modeling of cold-air inhalation from nasal cavities to the distal lung: Insights for athlete health and performance
Results in Engineering,
Год журнала:
2024,
Номер
23, С. 102475 - 102475
Опубликована: Июнь 26, 2024
In
cold
environments,
athletes
are
frequently
susceptible
to
injuries
from
inhaling
and
dry
air,
posing
significant
health
risks.
Despite
abundant
prior
research
focusing
on
risk
analysis
prevention,
the
existing
body
of
literature
has
predominantly
focused
heat
transfer
within
lung
airways
while
mainly
overlooking
broader
respiratory
tract.
This
pioneering
study
introduces
a
comprehensive
assessment
entire
system,
spanning
nasal
oral
cavities
larynx,
then
trachea,
extending
13th
generation
airways.
Employing
cutting-edge
Computational
Fluid
Dynamics
(CFD)
techniques,
investigation
operates
Large
Eddy
Simulation
(LES)
integrated
with
an
algebraic
wall-modeled
LES
subgrid-scale
model
simulate
human
lung.
approach
provides
detailed
insight
into
complex
dynamics
thermoregulation
in
environments.
By
offering
temperature,
flux,
Nusselt
number
static
pressure
profiles
throughout
this
fundamentally
advances
our
understanding
physiological
responses
system
air
exposure.
These
findings
have
paramount
implications
for
athlete
performance,
shedding
light
complexities
cold-induced
challenges.
Moreover,
lays
solid
foundation
developing
more
effective
preventive
measures
strategies
optimizing
athletic
performance
weather
conditions.
Язык: Английский
A Comprehensive Numerical Study on the Transport and Deposition of Nasal Sprayed Pharmaceutical Aerosols in a Nasal‐To‐Lung Respiratory Tract Model
Particle & Particle Systems Characterization,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 23, 2024
Abstract
Utilizing
a
computed
tomography
(CT)‐based
realistic
nasal‐to‐lung
respiratory
tract
model
allows
for
comprehensive
investigation
of
the
transport
and
deposition
nasal
sprayed
aerosols.
This
study
has
three
main
objectives:
first,
to
determine
optimal
mesh
that
achieves
quickest
convergence
computational
fluid‐particle
dynamics
(CFPD)
simulations
by
assessing
performance
different
element
types,
sizes,
prism
boundary
layers;
second,
design
validate
numerical
method
compare
grid
data
with
structures
densities
simulation
result
validation;
finally,
observe
analyze
in
aid
development
medications.
involves
reverse‐engineering
anatomically
accurate
from
CT
scans.
Results
reveal
approach
minimum
calculation
time
is
polyhedral
hybrid
four
layers
SIMPLE
pressure‐velocity
coupling
scheme.
Furthermore,
observations
particle
vocal
cords'
location
contains
concentration
site
deposited
small
aerosols
due
turbulent
airflow
region.
The
diameters
target
each
region
are
concluded
end.
Язык: Английский