Molecules,
Год журнала:
2024,
Номер
29(5), С. 1106 - 1106
Опубликована: Март 1, 2024
The
analysis
of
enantiomers
in
food
has
significant
implications
for
safety
and
human
health.
Conventional
analytical
methods
employed
enantiomer
analysis,
such
as
gas
chromatography
high-performance
liquid
chromatography,
are
characterized
by
their
labor-intensive
nature
lengthy
times.
This
review
focuses
on
the
development
rapid
reliable
biosensors
food.
Electrochemical
optical
highlighted,
along
with
fabrication
materials.
determination
can
authenticate
products
ensure
safety.
Amino
acids
chiral
pesticides
specifically
discussed
important
substances
found
use
sensors
replaces
expensive
reagents,
offers
real-time
capabilities,
provides
a
low-cost
screening
method
enantiomers.
contributes
to
advancement
sensor-based
field
promotes
authenticity
Abstract
Chirality
is
a
universal
phenomenon
in
molecular
and
biological
systems,
denoting
an
asymmetric
configurational
property
where
object
cannot
be
superimposed
onto
its
mirror
image
by
any
kind
of
translation
or
rotation,
which
ubiquitous
on
the
scale
from
neutrinos
to
spiral
galaxies.
plays
very
important
role
life
system.
Many
molecules
body
show
chirality,
such
as
“codebook”
earth's
diversity‐DNA,
nucleic
acid,
etc.
Intriguingly,
living
organisms
hierarchically
consist
homochiral
building
blocks,
for
example,
l
‐amino
acids
d
‐sugars
with
unknown
reason.
When
chirality
interact
these
chiral
factors,
only
one
conformation
favors
positive
development
life,
that
is,
host
environment
can
selectively
conformations.
The
differences
interactions
are
often
manifested
recognition,
mutual
matching,
molecules,
means
stereoselectivity
produce
changes
pharmacodynamics
pathology.
Here,
latest
investigations
summarized
including
construction
applications
materials
based
natural
small
source,
biomacromolecules
sources,
material
synthesized
design
source.
Chemical Communications,
Год журнала:
2023,
Номер
59(78), С. 11631 - 11647
Опубликована: Янв. 1, 2023
Covalent
organic
frameworks
(COFs)
are
porous
and
crystalline
polymers,
which
have
found
usage
in
various
fields.
These
tailorable
through
the
introduction
of
diverse
functionalities
into
platform.
Indeed,
functionality
plays
a
key
role
their
different
applications.
However,
sometimes
functional
groups
not
compatible
with
reaction
conditions
or
can
compete
interfere
other
monomers
direct
synthetic
method.
Also,
pre-synthesis
bulky
moieties
COFs
negatively
affect
crystal
formation.
To
avoid
these
problems
post-synthetic
modification
(PSM)
approach
is
helpful
tactic.
assistance
this
strategy
size
be
tunable
stability
improved
without
considerable
effect
on
crystallite.
In
addition,
conductivity,
hydrophobicity/
hydrophilicity,
chirality
among
features
that
reformed
review,
types
PSM
strategies
based
recent
articles
been
divided
four
categories:
(i)
post-functionalization,
(ii)
post-metalation,
(iii)
chemical
locking,
(iv)
host-guest
post-modifications.
Post-functionalization
locking
methods
covalent
bond
formation
while
post-metalation
post-modifications,
non-covalent
bonds
formed.
potential
post-modified
energy
storage
conversion
(lithium-sulfur
batteries,
hydrogen
storage,
proton-exchange
membrane
fuel
cells,
water
splitting),
heterogeneous
catalysts,
food
safety
evaluation,
gas
separation,
environmental
domains
(greenhouse
capture,
radioactive
element
uptake,
remediation),
biological
applications
(drug
delivery,
biosensors,
biomarker
chiral
column
chromatography,
solid-state
smart
nanochannels)
discussed.
ACS Applied Materials & Interfaces,
Год журнала:
2024,
Номер
16(8), С. 10661 - 10670
Опубликована: Фев. 20, 2024
Chiral
covalent
organic
frameworks
(COFs)
hold
considerable
promise
in
the
realm
of
heterogeneous
asymmetric
catalysis.
However,
fine-tuning
pore
environment
to
enhance
both
activity
and
stereoselectivity
chiral
COFs
such
applications
remains
a
formidable
challenge.
In
this
study,
we
have
successfully
designed
synthesized
series
clover-shaped,
hydrazone-linked
COFs,
each
with
varying
number
accessible
pyrrolidine
catalytic
sites.
Remarkably,
efficiencies
these
aldol
reaction
between
cyclohexanone
4-nitrobenzaldehyde
correlate
well
sites
within
frameworks.
The
COF
featuring
nearly
one
moiety
at
nodal
point
demonstrated
excellent
yields
enantiomeric
excess
(ee)
values,
reaching
up
97
83%,
respectively.
findings
not
only
underscore
profound
impact
deliberately
controlled
on
but
also
offer
new
perspective
for
design
synthesis
advanced
efficient
Journal of Separation Science,
Год журнала:
2025,
Номер
48(2)
Опубликована: Фев. 1, 2025
ABSTRACT
Chiral
covalent
organic
frameworks
(CCOFs)
are
emerging
porous
materials
with
tunable
chiral
structures,
abundant
pores,
and
high
surface
areas,
gaining
significant
attentions
in
separation,
sensing,
asymmetric
catalysis.
This
review
summarizes
the
synthesis
methods
of
CCOFs
their
applications
recognition.
It
discusses
advantages
limitations
three
strategies,
including
post‐modification,
direct
synthesis,
chiral‐induced
synthesis.
The
also
highlights
potential
catalysis
for
efficient
purification,
detection,
molecules.
Challenges
future
directions
preparation
application
addressed,
aiming
to
guide
further
research
practical
applications.
