Miniaturized solid-phase extraction techniques in sample preparation applied to food matrices: A review
Microchemical Journal,
Год журнала:
2025,
Номер
213, С. 113794 - 113794
Опубликована: Апрель 27, 2025
Язык: Английский
Human Sputum Proteomics: Advancing Non-Invasive Diagnosis of Respiratory Diseases with Enhanced Biomarker Analysis Methods
International Journal of Translational Medicine,
Год журнала:
2024,
Номер
4(2), С. 309 - 333
Опубликована: Май 31, 2024
Many
ailments
can
be
diagnosed
while
they
are
asymptomatic,
meaning
that
the
patient
has
no
signs
or
symptoms
of
a
progressing
disease.
If
caught
in
their
initial
stage
formation,
these
disorders
effectively
treated,
leading
to
successful
outcomes;
curative
therapies
halt
illnesses
from
advancing,
thus
improving
quality
life
and
long-term
survival
patient.
Still,
cutting-edge
upgrades
precision
technologies
necessary
for
early,
reliable,
affordable,
rapid
disease
detection,
but
also
vital
well-being
people
future
global
public
health.
The
emerging
role
utility
non-invasive
repeatable
diagnostic
test
approaches
detection
health
conditions
have
been
exemplified
by
liquid
biopsies
based
on
genomic
biomarkers.
As
such,
biological
fluids
permit
any
measurable
molecular
indicator
signature
(e.g.,
proteins)
provide
valuable
information
an
individual’s
wellness
and/or
Among
bodily
secretions
used
diagnostics
is
sputum,
complex
viscous
gel-like
biopolymeric
network
gained
growing
recognition
as
rich
source
biomarkers
airway
infections
pulmonary
diseases,
serves
determinant
reveal
other
illnesses.
per
World
Health
Organization,
burden
respiratory
exacerbated
factors
ranging
considerable
subjection
air
pollution
occupational
contaminants
tobacco
smoking
second-hand
smoke,
addition
poor
socio-economic
status.
Due
likely
increase
determinants,
tract
rise,
affecting
many
individuals,
putting
stress
healthcare
facilities
services
worldwide.
aim
this
study
was
perform
narrative
review
sputum
constituents
with
emphasis
proteins
glycoproteins
assessed
possible
lung
organ
diseases.
A
search
conducted
using
mucus,
proteomics,
biomarkers,
point-of-care
testing
keywords
employing
Google,
PubMed
(MEDLINE),
Web
Science,
selecting
most
referenced
related
papers
last
decade.
We,
therefore,
highlight
need
use
expectorated
induced
specimens
routine
sample
protein
diagnose
chronic
disorders,
predict
inflammation
progression,
well
monitor
effectiveness
treatments.
Further,
we
discuss
urgent
fast
reliable
methods
detect
quantify
crucial
specimens,
limitations
faced
when
dealing
matrices.
Язык: Английский
Human Sputum Proteomics: Advancing Non-Invasive Diagnosis of Respiratory Diseases with Enhanced Biomarker Analysis Methods
Опубликована: Апрель 29, 2024
Many
ailments
can
be
diagnosed
while
they
are
asymptomatic,
meaning
that
the
patient
has
no
signs
or
symptoms
of
a
progressing
disease.
If
caught
in
their
initial
stage
formation,
these
maladies
effectively
treated,
leading
to
successful
outcomes;
curative
therapies
halt
illnesses
from
advancing,
thus
improving
quality
life,
and
long-term
survival
patient.
Still
cutting-edge
upgrades
precision
technologies
necessary
for
early,
reliable,
affordable,
rapid
disease
detection,
but
also
vital
well-being
people
future
global
public
health.
The
emerging
role
utility
non-invasive
repeatable
diagnostic
test
approaches
detection
health
conditions
been
liquid
biopsies
based
on
genomic
biomarkers.
As
such,
biological
fluids
permit
any
measurable
molecular
indicator
signature
(e.g.,
proteins),
provide
valuable
information
individual’s
wellness
and/or
Among
bodily
secretions
used
diagnostics
is
sputum,
complex
viscous
gel-like
biopolymeric
network,
gained
growing
recognition
as
rich
source
biomarkers
airway
infections,
pulmonary
diseases,
serves
determinant
reveal
other
illnesses.
per
World
Health
Organization,
burden
respiratory
exacerbated
by
factors,
ranging
considerable
subjection
air
pollution
occupational
contaminants,
tobacco
smoking
second-hand
smoke,
addition
poor
socio-economic
status.
Due
likely
increase
determinants,
tract
rise,
affecting
many
individuals,
putting
stress
healthcare
facilities
services
worldwide.
We
therefore
highlight
need
use
expectorated
induced
sputum
specimens
routine
sample
testing
protein
diagnose
chronic
maladies,
predict
inflammation
progression,
well
monitor
effectiveness
treatments.
Further,
we
discuss
urgency
fast
reliable
point-of-care
methods
detect
quantify
crucial
specimens,
limitations
faced
when
dealing
with
matrices.
Язык: Английский
A Comprehensive Review on Capillary Electrophoresis–Mass Spectrometry in Advancing Biomolecular Research
Electrophoresis,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 7, 2024
ABSTRACT
This
review
provides
an
in‐depth
exploration
of
capillary
electrophoresis–mass
spectrometry
(CE–MS)
in
biomolecular
research
from
2020
to
2024.
CE–MS
emerges
as
a
versatile
and
powerful
tool
due
its
numerous
advantages,
facilitating
the
analysis
various
biomolecules,
including
proteins,
peptides,
oligonucleotides,
other
metabolites,
such
lipids,
carbohydrates,
or
amines,
among
others.
The
extends
CE
modes
interfaces
for
coupling,
offering
comprehensive
insights
into
their
applications
within
research.
Furthermore,
it
effectively
summarizes
conditions
employed
while
also
addressing
critical
aspects
sample
preparation
requirements.
Despite
highlights
gap
between
discovery
practical
implementation,
underscoring
need
large‐scale
validation
method
standardization
fully
realize
potential
Язык: Английский
The potential of new solvents and materials in the context of green analytical chemistry
Advances in Sample Preparation,
Год журнала:
2023,
Номер
8, С. 100096 - 100096
Опубликована: Сен. 25, 2023
Язык: Английский
On-line aptamer affinity solid-phase extraction capillary electrophoresis-mass spectrometry for the determination of SARS-CoV-2 nucleocapsid protein
Microchemical Journal,
Год журнала:
2024,
Номер
unknown, С. 112505 - 112505
Опубликована: Дек. 1, 2024
Язык: Английский
Screening, identification, and application of aptamers against allergens in food matrices
Critical Reviews in Food Science and Nutrition,
Год журнала:
2024,
Номер
unknown, С. 1 - 26
Опубликована: Дек. 11, 2024
Food
allergies
have
become
one
of
the
most
pressing
issues
in
food
safety
and
public
health
globally
along
with
their
incidence
increasing
recent
years.
The
reliable
recognition
allergens
from
different
sources,
especially
food-hidden
allergens,
is
essential
for
preventing
controlling
allergies.
Recently,
aptamers,
as
emerging
elements,
gained
considerable
attention
allergy,
detection
allergens.
This
review
systematically
summarizes
latest
progress
screening,
identification,
application
aptamers
against
over
past
five
We
first
introduce
a
brief
overview
allergy
followed
by
detailed
focus
on
aptamers'
research
broadly
based
major
categories
Big-8
allergens:
highlighting
newly
screened
applied
systematic
evolution
ligands
exponential
enrichment
(SELEX)
strategies,
emphasizing
practical
applications
including
aptasensors,
inhibitors,
or
affinity
adsorptions.
Finally,
remaining
challenges
future
exploitations
faced
are
comprehensively
discussed
depicted.
holds
promise
inspiring
broader
range
researchers
to
gain
an
in-depth
understanding
assisted
aptamer
facilitate
improved
biochemical
analyses
successful
application.
Язык: Английский