Uncovering the Mechanisms of Intracellular Membrane Trafficking by Reconstituted Membrane Systems DOI Creative Commons
Shuhan Chen, Yinghui Liu, Haijia Yu

и другие.

Membranes, Год журнала: 2025, Номер 15(5), С. 154 - 154

Опубликована: Май 16, 2025

Intracellular membrane trafficking that transports proteins, lipids, and other substances between organelles is crucial for maintaining cellular homeostasis signal transduction. The imbalance of leads to various diseases. It challenging uncover the mechanisms complicated dynamic process at or animal levels. applications functional reconstituted systems, which can mimic intracellular compartments in a clean simplified pattern, tremendously facilitate our understanding process. In this review, we summarize vitro models, including liposomes, nanodiscs, single-vesicle platforms, elucidating molecular govern vesicle fusion non-vesicular lipid transport, key steps trafficking. This review highlights how reconstitution approaches contribute illustrating protein-mediated choreography membranes.

Язык: Английский

Uncovering the Mechanisms of Intracellular Membrane Trafficking by Reconstituted Membrane Systems DOI Creative Commons
Shuhan Chen, Yinghui Liu, Haijia Yu

и другие.

Membranes, Год журнала: 2025, Номер 15(5), С. 154 - 154

Опубликована: Май 16, 2025

Intracellular membrane trafficking that transports proteins, lipids, and other substances between organelles is crucial for maintaining cellular homeostasis signal transduction. The imbalance of leads to various diseases. It challenging uncover the mechanisms complicated dynamic process at or animal levels. applications functional reconstituted systems, which can mimic intracellular compartments in a clean simplified pattern, tremendously facilitate our understanding process. In this review, we summarize vitro models, including liposomes, nanodiscs, single-vesicle platforms, elucidating molecular govern vesicle fusion non-vesicular lipid transport, key steps trafficking. This review highlights how reconstitution approaches contribute illustrating protein-mediated choreography membranes.

Язык: Английский

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