Recent advances in meglumine catalyzed organic synthesis: A comprehensive review
Synthetic Communications,
Год журнала:
2024,
Номер
54(16), С. 1285 - 1310
Опубликована: Авг. 1, 2024
Meglumine,
an
amino
sugar
alcohol
compound,
has
recently
emerged
as
a
promising
catalyst
in
various
organic
transformations
due
to
its
unique
properties.
This
review
provides
comprehensive
overview
of
the
applications
meglumine
synthesis,
highlighting
their
efficiency,
versatility,
and
mechanistic
insights.
Key
examples
reactions
catalyzed
by
meglumine,
including
aldol
condensation,
Michael
addition,
Mannich
reaction,
other
one-pot
multicomponent
condensation
reaction
are
discussed
along
with
pathways
synthetic
strategies.
Additionally,
recent
advancements
future
perspectives
field
explored.
Язык: Английский
An efficient, green and solvent-free three-component synthesis of 2,4,6-triarylpyridines utilizing ZSM-5 as a heterogeneous catalyst
Synthetic Communications,
Год журнала:
2024,
Номер
unknown, С. 1 - 11
Опубликована: Сен. 12, 2024
Язык: Английский
Synthesis of Isoxazol-5-One Derivatives Catalyzed by Amine-Functionalized Cellulose
Organics,
Год журнала:
2024,
Номер
5(4), С. 378 - 394
Опубликована: Окт. 12, 2024
In
this
contribution,
propylamine-functionalized
cellulose
(Cell-Pr-NH2)
was
employed
as
the
catalyst
in
three-component
reaction
between
hydroxylamine
hydrochloride
and
various
types
of
aryl/heteroaryl
aldehydes,
ethyl
acetoacetate/ethyl
4-chloroacetoacetate,
or
3-oxohexanoate.
The
result
these
experiments
formation
3,4-disubstituted
isoxazol-5(4H)-one
heterocycles.
desired
five-membered
heterocyclic
compounds
were
obtained
good
to
high
yields
at
room
temperature.
investigation
different
solvents
led
us
conclusion
that
water
is
best
solvent
perform
current
one-pot,
reactions.
Attempts
find
optimal
loading
clearly
showed
14
mg
cell-Pr-NH2
seems
be
sufficient
carry
out
This
method
has
highlighted
some
principles
green
chemistry
including
less
waste
generation,
atom
economy,
use
an
environmentally
friendly
solvent,
energy
saving.
Purification
without
chromatographic
methods,
mild
conditions,
simple
work-up,
low-cost
medium,
saving
time,
obtainable
precursors
are
other
notable
features
one-pot
fashion.
Язык: Английский
Synthesis, Properties, and Biological Activity of Benzothiadiazine
Advances in bioinformatics and biomedical engineering book series,
Год журнала:
2024,
Номер
unknown, С. 317 - 346
Опубликована: Ноя. 27, 2024
Heterocyclic
compounds
are
ubiquitous
in
biologically
active
compounds,
including
many
drugs.
Benzothiadiazine
is
a
class
of
sulphur
and
nitrogen-containing
heterocyclic
comprised
benzene
ring
fused
with
thiadiazine.
rings
appear
marketed
drugs,
such
as
bendroflumethiazide,
chlorothiazide,
cyclothiazide,
hydrochlorothiazide,
diazoxide,
which
popularly
known
for
their
diuretic
activity.
The
has
diverse
pharmacological
activity,
anti-cancer,
antifungal,
antimicrobial,
anthelmintic,
hypolipidaemic,
antidiabetic
This
chapter
focuses
on
the
chemistry,
synthetic
methods,
bioactivity
different
benzothiadiazine.
Furthermore,
updates
patents
clinical
trials
have
also
been
summarized
present
chapter.
Язык: Английский