Developmental exposure to cannabis compromises dopamine system function and behavior DOI Creative Commons
Marcello Solinas, Miriam Melis

Current Opinion in Behavioral Sciences, Год журнала: 2024, Номер 59, С. 101442 - 101442

Опубликована: Авг. 30, 2024

With the expanding legalization and decriminalization, cannabis price has decreased, its use increased along with content of main ingredient, THC. Although prevalence rates for consumption during adolescence appear unchanged, more potent availability powerful synthetic cannabinoids have enhanced health risks associated use. The pregnancy also risen because availability/acceptability misconception that is safe. Evidence shows development cognitive deficits mental illnesses. Particularly, exposure to in utero or derails normal dopamine system produces aberrant behaviors. In this review, we discuss long-term impact THC on behaviors related mesolimbic function, highlight areas research deserve investigation future.

Язык: Английский

Prefrontal oscillatory slowing in early-course schizophrenia is associated with worse cognitive performance and negative symptoms: a TMS-EEG study DOI
Francesco Donati,

Ahmad Mayeli,

Bruno Andry Nascimento Couto

и другие.

Biological Psychiatry Cognitive Neuroscience and Neuroimaging, Год журнала: 2024, Номер unknown

Опубликована: Июль 1, 2024

Язык: Английский

Процитировано

3

Treatment of Cognitive Impairment Associated with Schizophrenia Spectrum Disorders: New Evidence, Challenges, and Future Perspectives DOI Creative Commons
Irene Calzavara‐Pinton, Gabriele Nibbio, Sergio Barlati

и другие.

Brain Sciences, Год журнала: 2024, Номер 14(8), С. 791 - 791

Опубликована: Авг. 6, 2024

Cognitive impairment associated with schizophrenia (CIAS) represents one of the core features disorder and has a significant impact on functional rehabilitation outcomes people living spectrum disorders (SSD). The aim this critical review is to highlight most recent evidence effective treatments available for CIAS, discuss current challenges in field, present future perspectives that may help overcome them. Concerning psychopharmacological approaches, among indicated strategies management prevention CIAS favor second-generation antipsychotic medications avoid long-term high-dose anticholinergic benzodiazepines. Moreover, non-pharmacological approaches such as cognitive remediation physical exercise-based programs represent evidence-based interventions treatment have shown reliable effectiveness both outcomes. These treatments, however, are still delivered accessing mental health services diagnosis an uneven manner, even high-income countries. Academic clinical partnership collaboration, well advocacy from service users, families, carers, stakeholders' organizations could reduce bench bedside gap CIAS. Future include development novel pharmacological agents be implementation technologies telemedicine virtual reality delivery improve accessibility engagement, further research field non-invasive brain stimulation.

Язык: Английский

Процитировано

2

Reinventing Schizophrenia. Updating the Construct A Three-Year International Project DOI

Rajiv Tandon

Asian Journal of Psychiatry, Год журнала: 2024, Номер 97, С. 104107 - 104107

Опубликована: Июнь 5, 2024

Язык: Английский

Процитировано

2

Is self-disturbance in schizophrenia due to inter- and intra-hemispheric white matter dysconnectivity? DOI Creative Commons
Henry A. Nasrallah

Schizophrenia Research, Год журнала: 2024, Номер 270, С. 129 - 131

Опубликована: Июнь 19, 2024

Язык: Английский

Процитировано

2

Developmental exposure to cannabis compromises dopamine system function and behavior DOI Creative Commons
Marcello Solinas, Miriam Melis

Current Opinion in Behavioral Sciences, Год журнала: 2024, Номер 59, С. 101442 - 101442

Опубликована: Авг. 30, 2024

With the expanding legalization and decriminalization, cannabis price has decreased, its use increased along with content of main ingredient, THC. Although prevalence rates for consumption during adolescence appear unchanged, more potent availability powerful synthetic cannabinoids have enhanced health risks associated use. The pregnancy also risen because availability/acceptability misconception that is safe. Evidence shows development cognitive deficits mental illnesses. Particularly, exposure to in utero or derails normal dopamine system produces aberrant behaviors. In this review, we discuss long-term impact THC on behaviors related mesolimbic function, highlight areas research deserve investigation future.

Язык: Английский

Процитировано

2