Cattle Genomics: Aurochs Admixture in East Asia

Animal Research and One Health, Год журнала: 2025, Номер unknown

Опубликована: Фев. 12, 2025

Язык: Английский

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Admixture and selection offer insights for the conservation and breeding of Guyuan cattle

BMC Biology, Год журнала: 2025, Номер 23(1)

Опубликована: Май 13, 2025

The admixture between taurine and indicine cattle increases breed diversity provides new genetic resources for human natural selection. climate of northwestern China is typified by cold arid conditions, in this region are primarily breeds. However, Guyuan inhabit a transitional zone China, semi-arid semi-humid climates. It hypothesized that have little ancestry. These results suggest valuable resource. We established conservation population their native habitat. found were an 78.09% East Asian (EAT) 20.26% (EAI) ancestries. was dated to 255 years ago. Notably, we identified as unique resource, representing northern central Chinese with distinct proportions. revealed the selection signals excess EAT ancestry associated reproduction, immunity, body length, adaptation, pigmentation, muscle development, residual feed intake, fat deposition EAI disease resistance. Remarkably, discovered single nucleotide polymorphisms (SNPs) promoter regions RBM39 NEK6 genes, which may play key roles regulating development Our newly ancestries remain resource breeding.

Язык: Английский

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Revisiting Aurochs Haplogroup C: Paleogenomic Perspectives from Northeastern China

Genes, Год журнала: 2025, Номер 16(6), С. 639 - 639

Опубликована: Май 27, 2025

Background/Objectives: Aurochs (Bos primigenius), one of the earliest and largest herbivores domesticated by humans, were widely distributed in Eurasia North Africa during Pleistocene Holocene. Studies aurochs China have focused mainly on Northeastern region. Previous studies suggested that haplogroup C is a unique to China, but recent shown this not case. We compiled all data revisit classification C. Methods: In study, we obtained 13 nearly complete mitochondrial genomes from Late early Holocene bovine samples through fossil sample collection, ancient DNA extraction, library construction, high-throughput sequencing. Based acquired combination with previously published data, phylogenetic status, lineage divergence time, population dynamics analyzed. Results: Phylogenetic analyses time estimations suggest current definition overly inclusive, necessitating refined reclassification haplogroup. also estimated using Bayesian skyline plots found maternal effective size increased significantly Marine Isotope Stage 5 (MIS5), began decrease second half MIS3 before they eventually became extinct. Conclusions: Our results provide new molecular evidence China.

Язык: Английский

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Paleogenomic research reintroduces extinct East Asian aurochs to our sights

Science Bulletin, Год журнала: 2024, Номер unknown

Опубликована: Дек. 1, 2024

Язык: Английский

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