Environment International,
Год журнала:
2020,
Номер
140, С. 105750 - 105750
Опубликована: Апрель 29, 2020
Coexposure
of
MPs
and
other
contaminants
adsorbed
from
the
environment
has
raised
many
attentions,
but
understanding
combined
effects
plastic
additives
are
limited.
Butylated
hydroxyanisole
(BHA),
a
widely
used
synthetic
phenolic
antioxidant
in
plastics,
gained
high
concerns
due
to
their
unintended
environmental
release
potential
threat
aquatic
organisms.
This
study
was
conducted
reveal
influences
on
bioaccumulation
developmental
toxicity
BHA
zebrafish
larvae.
As
result,
promoted
accumulation
larvae
enhanced
development
manifested
by
reduced
hatching
rates,
increased
malformation
rates
decreased
calcified
vertebrae.
Although
concentration
not
sufficient
cause
obvious
toxicity,
impacts
thyroid
hormones
status
might
contribute
aggravated
join
toxicity.
The
metabolomic
mechanism
revealed
be
that
coexposure
affected
via
disturbing
metabolism
arachidonic
acid,
glycerophospholipid,
lipids.
Our
results
emphasized
MPs,
even
at
nontoxic
concentrations,
combination
with
caused
health
risk
should
ignored.
International Journal of Environmental Research and Public Health,
Год журнала:
2020,
Номер
17(5), С. 1509 - 1509
Опубликована: Фев. 26, 2020
Fragmented
or
otherwise
miniaturized
plastic
materials
in
the
form
of
micro-
nanoplastics
have
been
nagging
environmental
concern.
Perturbation
organismal
physiology
and
behavior
by
widely
documented
for
marine
invertebrates.
Some
these
effects
are
also
manifested
larger
vertebrates
such
as
fishes.
More
recently,
possible
on
mammalian
gut
microbiota
well
host
cellular
metabolic
toxicity
reported
mouse
models.
Human
exposure
to
occurs
largely
through
ingestion,
found
food
derived
from
packaging,
but
a
less
well-defined
manner
though
inhalation.
The
pathophysiological
consequences
acute
chronic
system,
particularly
humans,
yet
unclear.
In
this
review,
we
focus
recent
findings
related
potential
detrimental
demonstrated
models
human
cell
lines.
prevailing
data
suggest
that
accumulation
tissues
would
likely
negative,
unclear
long-term
consequences.
There
is
need
systemic
due
be
better
illuminated,
underlying
mechanisms
defined
further
work.
Particle and Fibre Toxicology,
Год журнала:
2020,
Номер
17(1)
Опубликована: Июнь 8, 2020
Given
the
global
abundance
and
environmental
persistence,
exposure
of
humans
(aquatic)
animals
to
micro-
nanoplastics
is
unavoidable.
Current
evidence
indicates
that
can
be
taken
up
by
aquatic
organism
as
well
mammals.
Upon
uptake,
reach
brain,
although
there
limited
information
regarding
number
particles
reaches
brain
potential
neurotoxicity
these
small
plastic
particles.Earlier
studies
indicated
metal
metal-oxide
nanoparticles,
such
gold
(Au)
titanium
dioxide
(TiO2)
also
exert
a
range
neurotoxic
effects.
similarities
between
chemically
inert
metal(oxide)
nanoparticles
particles,
this
review
aims
provide
an
overview
reported
effects
in
different
species
vitro.
The
combined
data,
fragmentary,
indicate
induce
oxidative
stress,
potentially
resulting
cellular
damage
increased
vulnerability
develop
neuronal
disorders.
Additionally,
result
inhibition
acetylcholinesterase
activity
altered
neurotransmitter
levels,
which
both
may
contribute
behavioral
changes.Currently,
systematic
comparison
particle
types,
shapes,
sizes
at
concentrations
durations
lacking,
but
urgently
needed
further
elucidate
hazard
risk
nanoplastics.
Progress in Earth and Planetary Science,
Год журнала:
2021,
Номер
8(1)
Опубликована: Янв. 22, 2021
Abstract
Microplastic
pollutes
water,
land,
air,
and
groundwater
environments
not
only
visually
but
also
ecologically
for
plants,
animals,
humans.
has
been
reported
to
act
as
vectors
by
sorbing
pollutants
contributing
the
bioaccumulation
of
pollutants,
particularly
in
marine
ecosystems,
organisms,
subsequently
food
webs.
The
inevitable
exposure
microplastic
humans
emphasises
need
review
potential
effects,
pathways,
toxicity
toward
human
health.
Therefore,
this
was
aimed
reveal
risks
pollutant
sorption
humans,
well
dominant
types
sorbed
microplastic,
that
are
bioaccumulated
living
organisms
ecosystem.
possible
factors
influencing
ecosystems
were
reviewed.
revealed
prevailing
abundance
geographical
distribution
aquatic
environment
globally.
literature
characteristics,
chemical
interactions,
water
properties
played
a
role
microplastic.
evidence
posing
direct
medical
threat
is
still
lacking
albeit
substantial
health
hazards
microplastic-associated
monomers,
additives,
pollutants.
This
recommends
future
research
on
existing
knowledge
gaps
research,
which
include
