Occurrence and distribution of azithromycin in wastewater treatment plants, seawater, and sediments of the northern part of the Persian Gulf around Bushehr port: A comparison with Pre-COVID 19 pandemic

Chemosphere, Год журнала: 2022, Номер 307, С. 135996 - 135996

Опубликована: Авг. 12, 2022

Язык: Английский

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Comprehensive micropollutant characterization of wastewater during Covid-19 crisis in 2020: Suspect screening and environmental risk prioritization strategy

The Science of The Total Environment, Год журнала: 2023, Номер 873, С. 162281 - 162281

Опубликована: Фев. 22, 2023

Micropollutants monitoring in wastewater can serve as a picture of what is consuming society and how it impact the aquatic environment. In this work, suspect screening approach was used to detect known unknown contaminants samples collected from two treatment plants (WWTPs) located Basque Country (Crispijana Alava, Galindo Vizcaya) during weekly sampling campaigns, which included months April July 2020, part confinement period caused by COVID-19. To that aim, high-resolution mass spectrometry collect full-scan data-dependent tandem spectra water using database containing >40,000 chemical substances. The presence > 80 confirmed (level 1) quantified both WWTP samples, while at least 47 compounds were tentatively identified (2a). Among concern, an increase occurrence some for COVID-19 disease treatment, such lopinavir hydroxychloroquine, observed lockdown. A prioritization strategy environmental risk assessment carried out considering only effluents Crispijana WWTPs. scored based on removal efficiency, estimated persistency, bioconcentration factor, mobility, toxicity potential frequency detection samples. With approach, 33 (e.g. amantadine, clozapine or lopinavir) found be considered key analyzed their concentration, toxicity. Additionally, antimicrobial (RQ-AR) antiviral (EDRP) certain evaluated, where ciprofloxacin fluconazole represented medium antibiotic resistance (1 RQ-AR 0.1) ecosystems. Regarding mixture toxicity, computed sum toxic unit values different (> suggest interactions between need future assessments.

Язык: Английский

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A One-Health environmental risk assessment of contaminants of emerging concern in London’s waterways throughout the SARS-CoV-2 pandemic

Environment International, Год журнала: 2023, Номер 180, С. 108210 - 108210

Опубликована: Сен. 14, 2023

The SARS-CoV-2 pandemic had huge impacts on global urban populations, activity and health, yet little is known about attendant consequences for river ecosystems. We detected significant changes in occurrence risks from contaminants of emerging concern (CECs) waterways across Greater London (UK) during the pandemic. were able to rapidly identify monitor large numbers CECs n = 390 samples 2019-2021 using novel direct-injection liquid chromatography-mass spectrometry methods scalable targeted analysis, suspect screening prioritisation CEC risks. A total 10,029 measured environmental concentrations (MECs) obtained 66 unique CECs. Pharmaceutical MECs decreased lockdown 2020 R. Thames (p ≤ 0.001), but then increased significantly 2021 0.01). For tributary rivers, Lee, Beverley Brook, Wandle Hogsmill most impacted, primarily via wastewater treatment plant effluent combined sewer overflows. In particular, pharmaceutical MEC trends generally correlated with NHS prescription statistics, likely reflecting limited dilution. Suspect ∼ 1,200 compounds tentatively identified 25 additional at five impacted sites, including metabolites such as O-desmethylvenlafaxine, an EU Watch List compound. Lastly, risk quotients (RQs) ≥ 0.1 calculated 21 whole freshwater catchment, which seven medium (RQ 1.0) three high-risk category 10), imidacloprid 19.6), azithromycin (15.7) diclofenac (10.5). This largest spatiotemporal dataset its kind any major capital city globally first London, representing 16 % population England, delivering a foundational One-Health case study third Europe

Язык: Английский

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Wastewater-based epidemiology as a surveillance tool to assess human consumption of psychotropic substances: Alcohol, nicotine and caffeine as case studies

TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 167, С. 117230 - 117230

Опубликована: Авг. 16, 2023

Wastewater-based epidemiology (WBE) is used as a surveillance tool to provide data on public health, drug use, exposure chemicals and lifestyle habits. This approach can be monitor the achievement of United Nations Sustainable Development Goals, such reducing alcohol consumption use tobacco. In addition, it applied total caffeine assess levels according recommended daily safety limit suggested by European Food Safety Authority. The purpose this review was summarize discuss analytical protocols for determination alcohol, nicotine, WBE biomarkers in wastewater. requirements these were thoroughly investigated. Furthermore, back-calculated population reviewed. Finally, challenges identified, future directions proposed fill knowledge gaps improve quality information obtained from approach.

Язык: Английский

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No party, no drugs? Use of stimulants, dissociative drugs, and GHB/GBL during the early COVID-19 pandemic

International Journal of Drug Policy, Год журнала: 2022, Номер 102, С. 103582 - 103582

Опубликована: Янв. 5, 2022

Язык: Английский

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