Water,
Год журнала:
2023,
Номер
15(12), С. 2276 - 2276
Опубликована: Июнь 17, 2023
Herbicides
with
glyphosate
(GLY)
as
an
active
ingredient
(a.i.)
are
increasingly
used,
and
GLY
is
currently
the
most
used
herbicide
in
world.
Consequently,
its
residues
have
often
been
found
aquatic
ecosystems.
Investigating
how
this
substance
affects
species
a
priority
ecotoxicology
research,
especially
fish,
they
can
absorb
concentrate
toxins.
In
sense,
critical
review
was
performed,
synthesizing
data
from
peer-reviewed
bibliography,
reporting
on
toxicity
of
exposure
to
pure
glyphosate-based
herbicides
(GBHs),
using
zebrafish
animal
model.
The
concentrations
that
induced
toxic
effects
highly
variable,
some
exceeding
limits
determined
by
regulatory
agencies.
Globally,
relevant
reported
zebrafish,
namely,
teratogenic
incompatible
life,
which
translates
directly
into
increase
mortality.
Neurotoxicity,
genotoxicity,
changes
energy
metabolism
oxidative
stress,
immune
hormonal
system
dysfunction
impact
fish
reproduction
were
also
described.
conclusion,
both
GBHs
may
induce
damage
compromising
their
survival,
reproduction,
maintenance.
These
results
be
valid
applied
other
Ecotoxicology and Environmental Safety,
Год журнала:
2024,
Номер
278, С. 116432 - 116432
Опубликована: Май 9, 2024
Cadmium
(Cd)
pollution
is
a
serious
global
environmental
problem,
which
requires
concern
and
practical
solutions.
Microbial
remediation
has
received
widespread
attention
owing
to
advantages,
such
as
friendliness
soil
amelioration.
However,
Cd
toxicity
also
severely
deteriorates
the
performance
of
functional
microorganisms.
Analyzing
mechanism
bacterial
resistance
stress
will
be
beneficial
for
application
remediation.
In
this
study,
bacteria
strain,
up
1400
mg/L
resistance,
was
employed
identified
Proteus
mirabilis
Ch8
(Ch8)
through
whole
genome
sequence
analyses.
The
results
indicated
that
multiple
pathways
immobilizing
detoxifying
maintained
growth
under
stress,
possessed
high
extracellular
adsorption.
Firstly,
changes
in
surface
morphology
groups
cells
were
observed
different
conditions
SEM-EDS
FTIR
Under
100
Cd,
exhibited
aggregation
less
flagella;
biosorption
predominately
by
secreting
exopolysaccharides
(EPS)
no
significant
change
groups.
500
present
irregular
polymers
on
cell
surface,
some
with
wrapping
around;
capacity
outstanding
effects
(38.80
mg/g),
mainly
interacting
EPS.
Then,
significantly
enhanced
antioxidant
enzyme
activity
substance
content
conditions.
activities
SOD
CAT,
GSH
increased
245.47%,
179.52%,
241.81%,
compared
normal
condition.
Additionally,
induced
expression
Acr
A
Tol
C
(the
resistance-nodulation-division
(RND)
efflux
pump),
genes
(SodB,
SodC,
Tpx)
reduce
damage.
particular,
markedly
higher
levels
SodB
stress.
lays
foundation
its
solving
Environmental Science & Technology,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 5, 2024
Excessive
production
of
reactive
oxygen
species
(ROS)
induced
by
micro/nanoplastics
(MPs/NPs)
is
highly
toxic
to
microbes.
However,
the
mechanisms
underlying
ROS
generation
and
metabolic
regulation
within
anaerobic
guilds
remain
poorly
understood.
In
this
study,
we
investigated
effects
environmentally
relevant
levels
polypropylene
(PP)-MPs/NPs
on
oxidative
stress
microbial
ecology
during
digestion
(AD).
Electron
paramagnetic
resonance
spectroscopy
revealed
that
PP-MPs/NPs
elevated
concentrations
persistent
free
radicals
(EPFRs)
derived
hydroxyl
(•OH).
EPFRs
were
identified
as
primary
contributors
•OH
generation,
evidenced
a
high
Spearman
correlation
coefficient
(r
=
0.884,
p
<
0.001)
radical-quenching
studies.
The
formation
enhanced
86.2–100.9%,
resulting
in
decreased
cellular
viability
methane
(by
37.5–50.5%)
at
100
mg/g
TS
PP-MPs/NPs.
Genome-centric
metagenomic
metatranscriptomic
analyses
suggested
reassembly
community
structures,
re-evolution
functional
traits,
remodeling
interspecies
interactions.
Specifically,
shift
methanogen
consortia
from
hydrogenotrophic
Methanofollis
sp.
acetoclastic
Methanothrix
soehngenii,
primarily
because
latter's
diverse
ingestion
patterns,
electron
bifurcation
complexes,
ROS-scavenging
abilities.
Downregulation
genes
associated
with
antioxidative
defense
systems
(i.e.,
sodN,
katA,
osmC)
ROS-driven
redox
signal
transduction
pathways
(c-di-AMP
phosphorylation
signaling
pathways)
provided
insights
into
ROS-induced
dysregulation.
Our
findings
enhance
understanding
ecological
traits
under
MPs/NPs
stressors,
facilitating
control
toxicity
stabilization
AD
processes.
