ACS Applied Electronic Materials,
Год журнала:
2023,
Номер
5(11), С. 5831 - 5840
Опубликована: Ноя. 2, 2023
In
this
work,
we
used
a
commercial
manufacturing
process
to
obtain
WO3
semiconductor
gas
sensor
realize
NO2
detection
in
parts-per-billion
concentration
at
room
temperature
(25–27
°C).
The
radio-frequency
(RF)
sputtering
was
deposit
an
ultrathin
(down
5
nm)
sensing
layer.
With
suitable
control
of
the
deposition
ambient
and
postannealing
condition,
ultrathin-film
resistor
with
50-μm
line
width
can
detect
100
ppb
without
any
heating
setup.
Notably,
no
nanometer
is
required;
hence,
production
be
realized
by
current
flat-panel
display
technology.
By
modulating
investigated
influences
surface
roughness,
crystalline
hydroxyl
group
levels
on
response.
To
achieve
(ppb)
level
detection,
thickness
essential,
high-level
crystal
together
low-level
also
enhances
sensitivity
recovery.
humidity
effect
discussed
show
almost
unchanged
response
relative
(RH)
from
30
70%.
summary,
shows
good
performance,
including
high
sensitivity,
wide
detecting
range
(17
ppm
ppb),
fast
response/recovery
(30
s/∼21
s)
low
(0.68
ppm).
Finally,
enough
selectivity,
stability,
nondecayed
WO3-based
after
14
days
were
demonstrated.
Acta Ophthalmologica,
Год журнала:
2023,
Номер
101(8), С. 839 - 856
Опубликована: Ноя. 7, 2023
Globally
age-related
macular
degeneration
(AMD)
is
a
leading
cause
of
blindness
with
significant
impact
on
quality
life.
Geographic
atrophy
(GA)
the
atrophic
late
form
AMD
and
its
prevalence
increases
markedly
age
around
1
in
5
persons
aged
85
above
having
GA
at
least
one
eye.
Bilateral
leads
to
severe
visual
impairment
thus
posing
burden
patients,
careers
health
providers.
The
incidence
varies
across
different
geographic
regions,
highest
rates
those
European
ancestry.
Although
heterogeneity
definitions
reporting
strategy
can
explain
some
discrepancies,
data
overall
are
consistent
showing
lower
other
ethnicities
such
as
Asian
heritage.
This
present
unexplained
but
thought
be
due
existence
protective
factors
differences
eye
pigmentation,
diet,
environmental
exposures
genetic
variability.
review
covers
key
aspects
ocular
precursor
features
(large
drusen,
pigmentary
abnormalities
reticular
pseudo-drusen),
stage
that
have
been
known
associated
modifying
risk
including
systemic,
demographic,
environment,
ocular.
Understanding
global
epidemiology
scenario
crucial
for
prevention
management
patients
GA.
Lasers in Medical Science,
Год журнала:
2024,
Номер
39(1)
Опубликована: Май 27, 2024
Classifying
retinal
diseases
is
a
complex
problem
because
the
early
problematic
areas
of
disorders
are
quite
small
and
conservative.
In
recent
years,
Transformer
architectures
have
been
successfully
applied
to
solve
various
related
health
problems.
Age-related
macular
degeneration
(AMD)
diabetic
edema
(DME),
two
prevalent
diseases,
can
cause
partial
or
total
blindness.
Diseases
therefore
require
an
accurate
detection.
this
study,
we
proposed
Vision
(ViT),
Tokens-To-Token
(T2T-ViT)
Mobile
(Mobile-ViT)
algorithms
detect
choroidal
neovascularization
(CNV),
drusen,
normal
using
optical
coherence
tomography
(OCT)
images.
The
predictive
accuracies
ViT,
T2T-ViT
Mobile-ViT
achieved
on
dataset
for
classification
OCT
images
95.14%,
96.07%
99.17%
respectively.
Experimental
results
obtained
from
ViT
approaches
showed
that
superior
performance
with
regard
accuracy
in
comparison
others.
Overall,
it
has
observed
capacity
classify
high
diagnosis
diseases.
Antioxidants,
Год журнала:
2023,
Номер
12(7), С. 1368 - 1368
Опубликована: Июнь 29, 2023
Age-related
macular
degeneration
(AMD),
an
oxidative
stress-linked
neurodegenerative
disease,
leads
to
irreversible
damage
of
the
central
retina
and
severe
visual
impairment.
Advanced
age
long-standing
influence
stress
cellular
play
crucial
roles
in
AMD
etiopathogenesis.
Many
authors
emphasize
role
heterophagy,
autophagy,
mitophagy
maintaining
homeostasis
retina.
Relevantly
modifying
activity
both
macroautophagy
pathways
represents
one
new
therapeutic
strategies
AMD.
Our
review
provides
overview
antioxidative
presents
associations
between
dysregulations
these
molecular
mechanisms
The
performed
extensive
analysis
literature,
employing
PubMed
Google
Scholar,
complying
with
2013–2023
period,
using
following
keywords:
age-related
degeneration,
RPE
cells,
reactive
oxygen
species,
stress,
mitophagy.
Heterophagy,
retina;
however,
they
become
sluggish
dysregulated
contribute
development
progression.
In
retina,
also
NFE2L2
PGC-1α
proteins,
NFE2L2/PGC-1α/ARE
signaling
cascade,
Nrf2
factor,
p62/SQSTM1/Keap1-Nrf2/ARE
pathway,
circulating
miRNAs,
Yttrium
oxide
nanoparticles
experimentally
animal
studies.
