ACS Applied Bio Materials, Год журнала: 2023, Номер 6(10), С. 4403 - 4412
Опубликована: Сен. 28, 2023
A tripodal amine (TPA) with –OH, N, and S donors is synthesized to functionalize a core–shell carbon dot composite (FCDs@SiO2-TPA) for sensing application. The TPA characterized by spectroscopic spectrometric techniques, the Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), Brunauer–Emmett–Teller (BET), scanning electron microscopy (SEM), transmission (TEM), energy-dispersive X-ray spectra (EDS) techniques. has ability recognize mefenamic acid (MFA) selectively even in presence of other drugs like ibuprofen sodium, acetylsalicylic acid, naproxen diclofenac ketoprofen. It can also be used quantification MFA recording emission quenching response sample at λexc. = 350 nm λems. 460 (linear range 1–8 μM LOD 197 nM). density functional theory calculations 1H NMR titration suggest signal due photoinduced transfer via hydrogen bonding between probe MFA. FCDs@SiO2-TPA been demonstrated as reliable cost-effective detection pharmaceutical formulations, water samples, cow urine samples.
Язык: Английский