This
paper
underlines
the
critical
need
for
novel
diagnostic
techniques
against
increasing
worldwide
burden
of
neurodegenerative
disorders
(NDDs).
The
intricacies
Alzheimer's,
Parkinson's,
and
Huntington's
necessitate
very
accurate
sensitive
early
detection
strategies.
In
addition,
it
provides
an
essential
look
at
promise
role
nanotechnology
potential
nanoscale
material
technology
integration
to
revolutionize
preclinical
disease
diagnostics.
Furthermore,
allows
pinpoint
identification
biomarkers
pathological
alterations.
We
discussed
different
types
nanotools,
including
nanoparticles,
nanosensors,
imaging
agents,
nanomedicine.
process
metamorphosis,
however,
has
its
challenges.
development
these
cutting-edge
instruments
necessitates
careful
thought
on
issues
ethics,
safety,
biocompatibility.
Despite
limitations,
nanotools'
importance
in
changing
course
screening
is
undeniable.
ACS Sensors,
Год журнала:
2024,
Номер
9(9), С. 4469 - 4494
Опубликована: Сен. 9, 2024
Lung
cancer
remains
a
global
health
concern,
demanding
the
development
of
noninvasive,
prompt,
selective,
and
point-of-care
diagnostic
tools.
Correspondingly,
breath
analysis
using
nanobiosensors
has
emerged
as
promising
noninvasive
nose-on-chip
technique
for
early
detection
lung
through
monitoring
diversified
biomarkers
such
volatile
organic
compounds/gases
in
exhaled
breath.
This
comprehensive
review
summarizes
state-of-the-art
breath-based
diagnosis
employing
chemiresistive-module
supported
by
theoretical
findings.
It
unveils
fundamental
mechanisms
biological
basis
biomarker
generation
associated
with
cancer,
technological
advancements,
clinical
implementation
nanobiosensor-based
analysis.
explores
merits,
challenges,
potential
alternate
solutions
implementing
these
settings,
including
standardization,
biocompatibility/toxicity
analysis,
green
sustainable
technologies,
life-cycle
assessment,
scheming
regulatory
modalities.
highlights
nanobiosensors'
role
facilitating
precise,
real-time,
on-site
leading
to
improved
patient
outcomes,
enhanced
management,
remote
personalized
monitoring.
Additionally,
integrating
biosensors
artificial
intelligence,
machine
learning,
Internet-of-things,
bioinformatics,
omics
technologies
is
discussed,
providing
insights
into
prospects
intelligent
sniffing
nanobiosensors.
Overall,
this
consolidates
knowledge
on
breathomic
biosensor-based
screening,
shedding
light
its
significance
applications
advancing
medical
diagnostics
reduce
burden
hospitals
save
human
lives.
Advanced Quantum Technologies,
Год журнала:
2024,
Номер
7(3)
Опубликована: Янв. 18, 2024
Abstract
The
development
of
quantum‐enabled
photonic
technologies
has
opened
new
avenues
for
advanced
illumination
across
diverse
fields,
including
sensing,
computing,
materials,
and
integration.
This
review
highlights
how
Quantum‐enhanced
sensing
imaging
exploit
nonclassical
correlations
to
attain
unprecedented
accuracy
in
chaotic
environments.
As
well
as
guaranteeing
secure
communications,
quantum
cryptography,
protected
by
physical
principles,
ensures
unbreakable
cryptographic
key
exchange.
computing
speed
increases
exponentially,
previously
unimplementable
uses
classical
computers
become
feasible.
On‐chip
integration
enables
the
mass
production
components
pervasive
applications
facilitating
miniaturization
scalability.
A
powerful
flexible
platform
is
produced
when
systems
are
combined.
Quantum
spin
liquids
other
topological
materials
can
maintain
their
states
while
subject
decoherence.
Despite
challenges
with
decoherence,
production,
commercialization,
photonics
an
exciting
area
study
that
promises
lighting
techniques
impossible
conventional
optics.
To
realize
this
promise,
researchers
from
several
fields
must
work
together
solve
complex
technical
problems
decode
fundamental
physics.
Finally,
advances
have
potential
evolve
devices
cutting‐edge
methods
usher
a
age
options
based
on
dots.
ACS Synthetic Biology,
Год журнала:
2024,
Номер
13(6), С. 1600 - 1620
Опубликована: Июнь 6, 2024
Antimicrobial
resistance
(AMR)
poses
a
critical
global
One
Health
concern,
ensuing
from
unintentional
and
continuous
exposure
to
antibiotics,
as
well
challenges
in
accurate
contagion
diagnostics.
Addressing
AMR
requires
strategic
approach
that
emphasizes
early
stage
prevention
through
screening
clinical,
environmental,
farming,
livestock
settings
identify
nonvulnerable
antimicrobial
agents
the
associated
genes.
Conventional
diagnostics,
like
antibiotic
susceptibility
testing,
possess
drawbacks,
including
high
costs,
time-consuming
processes,
significant
manpower
requirements,
underscoring
need
for
intelligent,
prompt,
on-site
diagnostic
techniques.
Nanoenabled
artificial
intelligence
(AI)-supported
smart
optical
biosensors
present
potential
solution
by
facilitating
rapid
point-of-care
detection
with
real-time,
sensitive,
portable
capabilities.
This
Review
comprehensively
explores
various
types
of
nanobiosensors,
such
surface
plasmon
resonance
sensors,
whispering-gallery
mode
coherence
tomography,
interference
reflection
imaging
surface-enhanced
Raman
spectroscopy,
fluorescence
microring
tweezer
biosensors,
By
harnessing
unique
advantages
these
nanoenabled
revolutionary
paradigm
shift
diagnostics
can
be
achieved,
characterized
results,
sensitivity,
portability,
integration
Internet-of-Things
(IoT)
technologies.
Moreover,
enable
personalized
monitoring
detection,
significantly
reducing
turnaround
time
eliminating
human
resources
needed
sample
preservation
transportation.
Their
holistic
environmental
surveillance
further
enhances
capabilities
diverse
settings,
leading
improved
modern-age
healthcare
practices
more
effective
management
treatments.
Embracing
advanced
tools
promises
bolster
capacity
combat
safeguard
Health.
