The
contribution
of
increased
rainfall
frequency
and
intensity
towards
the
impacts
urban
pollution
is
gaining
more
attention
in
these
times
climate
change.
purpose
this
study
was
to
examine
toxicological
combined
sewers
overflows
a
municipal
effluent
discharge
sites
during
3
periods
(years)
varying
precipitations
freshwater
mussels
Elliptio
complanata.
Mussels
were
placed
benthic
cages
for
months
summer
at
2
overflow
8
km
downstream
including
an
upstream
site
three
consecutive
years
with
low
(164
mm),
medium
(182
mm)
high
(248
amounts
rain.
results
revealed
that
effects
mainly
influenced
by
suspended
matter
loadings
dissolved
components
lesser
extent.
Impacts
noticeable
reproduction
(vitellogenin),
genotoxicity,
neurotoxicity
(dopamine
serotonin
changes)
levels
addition
xenobiotic
biotransformation
glutathione
S-transferase
activity
metallothioneins
organic
heavy
metals
respectively.
produced
most
compared
Saint-Lawrence
River.
However,
could
become
problematic
dilution
systems
such
as
small
river
lakes.
Water Science & Technology,
Год журнала:
2024,
Номер
89(6), С. 1554 - 1569
Опубликована: Март 8, 2024
Abstract
Combined
sewer
overflows
(CSOs)
are
one
of
the
main
sources
pollution
in
urban
water
systems
and
significantly
impede
restoration
body
functionalities
within
rivers
lakes.
To
understand
research
frontier
trends
CSOs
comprehensively
systematically,
a
visual
statistical
analysis
literature
related
to
Web
Science
core
database
from
1990
2022
was
conducted
using
bibliometric
method
HistCite
Pro
VOSviewer.
The
results
reveal
total
1,209
pertinent
publications
2022,
quantity
CSOs-related
indicated
an
increasing
trend.
Investigations
distribution
fate
typical
pollutants
their
ecological
effects
on
receiving
waters
studies
control
technologies
(source
reduction,
process
control,
end-of-pipe
treatment)
current
focus
research.
based
source
reduction
monitoring
emerging
contaminants
at
forefront
scientific
investigations
CSOs.
This
study
systematically
summarized
topics
future
directions
CSOs,
thus
providing
reference
for
environment
management
In
this
study,
we
compared
a
wide
range
of
cell-based
bioassays
to
the
use
chemical
analysis
followed
by
exposure-activity
ratio
(EAR)
and
Toxicological
Prioritization
index
(ToxPi)
for
prioritizing
chemicals,
sites,
hazard
concerns
in
water
samples.
Surface
samples
were
collected
from
nine
sites
three
Central
Pennsylvania
streams
analyzed
targeted
list
compounds
emerging
concern
(CECs),
including
pesticides,
personal
care
products,
pharmaceuticals.
Cell-based
reporter
assays
evaluated
human
zebrafish
molecular
initiating
events
(MIEs)
endocrine
metabolic
disruption,
altered
lipid
metabolism,
oxidative
stress.
Bioassays
showed
that
29
out
40
had
at
least
one
site
with
activity
over
limit
detection.
The
receptors
exhibited
highest
number
above
effect-based
trigger
(EBT)
values
would
be
expected
cause
toxicity
Aryl
hydrocarbon
receptor
(AhR,
zebrafish),
Pregnane
X
Receptor
(PXR),
Estrogen
Receptor-beta
(ERB),
Androgen
(AR).
Characterizing
collection
their
bioactivity
aligned
closely
stream
which
collected,
Warriors
Mark
Run,
Halfmoon,
Spruce
Run
more
similar
than
other
streams.
sum
all
EARs
each
indicated
pharmaceutical
Carbamazepine
pesticides
Carbaryl
Atrazine
posed
greatest
concern.
However,
predicted
prioritization
based
on
individual
calculated
EAR
different
those
measured
bioassay,
indicating
biologically
active
chemicals
are
present
not
included
analytes.
Taken
together,
these
data
show
beneficial
whereas
mechanism-based
inclusive
known
as
well
unknown
contaminants
thus
overall
quality
prioritization.
