Evaluating survey techniques in wastewater-based epidemiology for accurate COVID-19 incidence estimation

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Июнь 10, 2024

Abstract Wastewater-based epidemiology (WBE) requires high-quality survey methods to determine the incidence of infections in catchment areas. In this study, wastewater necessary for comprehending infection by WBE are clarified. This clarification is based on correlation with number confirmed coronavirus disease 2019 (COVID-19) cases, considering factors such as handling non-detect data, calculation method representative values, analytical sensitivity, reproducibility, sampling frequency, and duration. Data collected from 15 samples per week two a half years using highly accurate analysis were regarded gold standard between severe acute respiratory syndrome 2 (SARS-CoV-2) RNA concentrations COVID-19 cases was analyzed Monte Carlo simulation under hypothetical situation where quality reduced. Regarding data handling, it appropriate replace estimates distribution, use geometric means calculate values. For SARS-CoV-2 samples, sensitive reproducible (non-detect rates < 40%; ≤ 0.4 deviation) surveying at least three preferably five considered desirable. Furthermore, conducting over period time that included 50 weeks necessary. A meets these criteria sufficient determination area. can offer additional insights into area, estimated 48% decrease visiting clinic following legal reclassification Japan.

Язык: Английский

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Wastewater-Based Estimation of Influenza a Virus Shedding Dynamics and Infection Cases Using the Presens Model

Опубликована: Янв. 1, 2024

Язык: Английский

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Wastewater-based effective reproduction number and prediction under the absence of shedding information

Environment International, Год журнала: 2024, Номер 194, С. 109128 - 109128

Опубликована: Ноя. 14, 2024

Estimating effective reproduction number (R

Язык: Английский

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Monitoring Influenza A (H1N1, H3N2), RSV, and SARS-CoV-2 Using Wastewater-Based Epidemiology: A 2-Year Longitudinal Study in an Indian Megacity Covering Omicron and Post-Omicron Phases

Food and Environmental Virology, Год журнала: 2024, Номер 17(1)

Опубликована: Ноя. 19, 2024

Язык: Английский

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Wastewater-based estimation of temporal variation in shedding amount of influenza A virus and clinically identified cases using the PRESENS model

Environment International, Год журнала: 2024, Номер 195, С. 109218 - 109218

Опубликована: Дек. 19, 2024

Язык: Английский

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