Growth of microbes in competitive lifestyles promotes increased ARGs in soil microbiota: insights based on genetic traits

Microbiome, Год журнала: 2025, Номер 13(1)

Опубликована: Янв. 13, 2025

The widespread selective pressure of antibiotics in the environment has led to propagation antibiotic resistance genes (ARGs). However, mechanisms by which microbes balance population growth with enrichment ARGs remain poorly understood. To address this, we employed microcosm cultivation at different (i.e., Oxytetracycline, OTC) stresses across concentrations from environmental clinical. Paired shot-gun metagenomics analysis and quantification bacterial growth, trait-based assessment soil microbiota was applied reveal association between key ARG subtypes, representative taxa, functional-gene features that drive ARGs. Our results illuminate resistome variation is closely associated growth. A non-monotonic change abundance richness observed over a concentration gradient none 10 mg/l. Soil exposed intermediate OTC 0.1 0.5 mg/l) showed greater increases total Community compositionally, i.e., Pseudomonadaceae considered boost increase It chromosomally carried kinds multidrug such as mexAB-oprM mexCD-oprJ could mediate intrinsic OTC. Streptomycetaceae shown better adaptive ability than other clinical concentrations. it contributed less represents stress-tolerant lifestyle grows slowly carries fewer In terms community genetic features, aggregated traits further indicates enhancement resource acquisition yield driving abundance. Moreover, optimizations energy production conversion, alongside streamlining bypass metabolic pathways, sub-inhibitory conditions. this study suggest competitive lifestyles are selected under stress nutrient scarcity. They possess substrate utilization capacity carry more ARGs, due they were faster growing leading This expanded application assessments understanding ecology propagation. And finding illustrated changes accompanied switching microbiome, theoretically supports control approach based on principle species exclusion.

Язык: Английский

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Mobile genetic elements mediate the cross-media transmission of antibiotic resistance genes from pig farms and their risks

The Science of The Total Environment, Год журнала: 2024, Номер 926, С. 172115 - 172115

Опубликована: Апрель 1, 2024

Язык: Английский

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Deciphering key traits and dissemination of antibiotic resistance genes and degradation genes in pharmaceutical wastewater receiving environments.

Water Research, Год журнала: 2025, Номер 275, С. 123241 - 123241

Опубликована: Фев. 2, 2025

Язык: Английский

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Occurrence, dissipation kinetics and environmental risk assessment of antibiotics and their metabolites in agricultural soils

Journal of Hazardous Materials, Год журнала: 2024, Номер 479, С. 135586 - 135586

Опубликована: Авг. 23, 2024

Antibiotics are among the emerging contaminants of greatest concern to scientific community. However, occurrence and behaviour their metabolites in soils have been scarcely studied. To address this research gap, study investigates occurrence, sorption, dissipation kinetics, environmental risk highly important antibiotics (sulfamethazine, sulfadiazine, sulfamethoxazole, trimethoprim) main Mediterranean agricultural soils. Batch experiments were conducted under natural conditions for 120 days. Five different kinetics models applied elucidate degradation. The sorption isotherms evaluated by three models. Most tested showed a good fit with Linear Isotherm model (R

Язык: Английский

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High-generation tetracyclines shifted microbial community composition and induced the emergence of antibiotic resistant bacteria in soil

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 135757 - 135757

Опубликована: Сен. 6, 2024

Язык: Английский

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Defense systems of soil microorganisms in response to compound contamination by arsenic and polycyclic aromatic hydrocarbons

The Science of The Total Environment, Год журнала: 2024, Номер 950, С. 175364 - 175364

Опубликована: Авг. 6, 2024

Язык: Английский

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Vertical variation of antibiotic resistance genes and their interaction with environmental nutrients in sediments of Taihu lake

Journal of Environmental Management, Год журнала: 2024, Номер 370, С. 122661 - 122661

Опубликована: Сен. 26, 2024

Язык: Английский

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Fluoranthene slow down sulfamethazine migration in soil via π-π interaction to increase the abundance of antibiotic resistance genes

Environmental Pollution, Год журнала: 2024, Номер 358, С. 124532 - 124532

Опубликована: Июль 10, 2024

Язык: Английский

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Pyraclostrobin repeated treatment altered the degradation behavior in soil and negatively affected soil bacterial communities and functions

Journal of Hazardous Materials, Год журнала: 2024, Номер 485, С. 136876 - 136876

Опубликована: Дек. 14, 2024

Язык: Английский

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Impact of arsenic and PAHs compound contamination on microorganisms in coking sites: From a community to individual perspective

Environmental Pollution, Год журнала: 2024, Номер 360, С. 124628 - 124628

Опубликована: Июль 27, 2024

Язык: Английский

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